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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cfpd</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень физиологии и патологии дыхания</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin Physiology and Pathology of Respiration</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1998-5029</issn><publisher><publisher-name>Дальневосточный научный центр физиологии и патологии дыхания</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.36604/1998-5029-2022-84-93-99</article-id><article-id custom-type="elpub" pub-id-type="custom">cfpd-1026</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАБЛЮДЕНИЯ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>SELECTED REPORTS</subject></subj-group></article-categories><title-group><article-title>Влияние жидкостей для электронных сигарет на дыхательную систему человека. Клиническое наблюдение пациента с EVALI</article-title><trans-title-group xml:lang="en"><trans-title>Influence of liquids for electronic cigarettes on the human respiratory system. Clinical observation of a patient with EVALI</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Михайловский</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Mikhailovskiy</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алексей Игоревич Михайловский, студент 6 курса лечебного факультета</p><p>675000, г. Благовещенск, ул. Горького, 95</p></bio><bio xml:lang="en"><p>Alexey I. Mikhailovskiy, 6th year Student of Medical Faculty</p><p>95 Gor'kogo Str., Blagoveshchensk, 675000, Russian Federation</p></bio><email xlink:type="simple">aleks_nord00@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Войцеховский</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Voytekhovskiy</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Валерий Владимирович Войцеховский, д-р мед. наук, доцент, зав. кафедрой госпитальной терапии с курсом фармакологии</p><p>675000, г. Благовещенск, ул. Горького, 95</p></bio><bio xml:lang="en"><p>Valeriy V. Voytsekhovskiy, MD, PhD, DSc (Med.), Associate Professor, Head of Department of Hospital Therapy with Pharmacology Course</p><p>95 Gor'kogo Str., Blagoveshchensk, 675000, Russian Federation</p></bio><email xlink:type="simple">voitsehovsckij@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лучникова</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Luchnikova</surname><given-names>T. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Татьяна Андреевна Лучникова, канд. мед. наук, доцент кафедры госпитальной терапии с курсом фармакологии</p><p>675000, г. Благовещенск, ул. Горького, 95</p></bio><bio xml:lang="en"><p>Tatiana A. Luchnikova, MD, PhD (Med.), Associate Professor of Department of Hospital Therapy with Pharmacology Course</p><p>95 Gor'kogo Str., Blagoveshchensk, 675000, Russian Federation</p></bio><email xlink:type="simple">tanechkaluch89@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования «Амурская государственная медицинская академия» Министерства здравоохранения Российской Федерации</institution></aff><aff xml:lang="en"><institution>Amur State Medical Academy</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>09</day><month>07</month><year>2022</year></pub-date><volume>0</volume><issue>84</issue><fpage>93</fpage><lpage>99</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Михайловский А.И., Войцеховский В.В., Лучникова Т.А., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Михайловский А.И., Войцеховский В.В., Лучникова Т.А.</copyright-holder><copyright-holder xml:lang="en">Mikhailovskiy A.I., Voytekhovskiy V.V., Luchnikova T.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cfpd.elpub.ru/jour/article/view/1026">https://cfpd.elpub.ru/jour/article/view/1026</self-uri><abstract><sec><title>Цель</title><p>Цель. Демонстрация клинического наблюдения EVALI из личной практики авторов.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Представлен краткий обзор литературы, посвященный влиянию жидкостей для электронных сигарет на дыхательную систему человека. Приведено клиническое наблюдение данной патологии.</p></sec><sec><title>Результаты</title><p>Результаты. Пациент Х., 19 лет, поступил в отделение торакальной хирургии с жалобами на одышку, кашель с кровохарканием. При компьютерной томографии в паренхиме легких обнаруживаются инфильтраты по всем полям с обширными участками «матового стекла». При фибробронхоскопии – в просвете бронхов незначительное количество геморрагических «корок» и геморрагического экссудата, катарально-геморрагический эндобронхит. Пациент – любитель электронных сигарет, чему сразу не было уделено внимание. Проводился дифференциальный диагноз с синдромом Гудпасчера, идиопатическим легочным гемосидерозом, системной красной волчанкой с поражением легких, ANCA-ассоциированными васкулитами. Так как имела место нефропатия и были отрицательными иммунологические данные других заболеваний, выставлен диагноз синдрома Гудпасчера. Биопсия почки не проводилась. Быстрая положительная динамика от гормональной терапии, отсутствие рецидивов и прогрессирования вызвали сомнения в данном диагнозе. После заболевания пациент отказался от приема электронных сигарет. Вновь обратились к анамнезу, где были указания на злоупотребление электронными сигаретами, после частого употребления которых и появилась развернутая клиническая картина заболевания, поэтому диагноз «синдром Гудпасчера» был снят, повреждение легких было расценено как проявление EVALI.</p></sec><sec><title>Заключение</title><p>Заключение. Приведенный клинический случай является подтверждением негативного влияния электронных курительных систем, повреждения легких у использующего их человека и демонстрирует трудности дифференциальной диагностики EVALI-синдрома.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. Demonstration of clinical observation of EVALI from the personal practice of the authors.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. A brief review of the literature on the effects of e-liquids on the human respiratory system is presented. Clinical observation of this pathology is given.</p></sec><sec><title>Results</title><p>Results. Patient H., 19 years old, was admitted to the Thoracic Surgery Department with complaints of shortness of breath, cough with hemoptysis. On computer tomography in lung parenchyma, infiltrates are found in all fields with extensive ground glass areas. Fibrobronchoscopy revealed in the lumen of the bronchi a small amount of hemorrhagic “crusts” and hemorrhagic exudate, catarrhal-hemorrhagic endobronchitis. The patient is a fan of electronic cigarettes, which was not immediately paid attention to. A differential diagnosis was made with Goodpasture's syndrome, idiopathic pulmonary hemosiderosis, systemic lupus erythematosus with lung involvement, and ANCA-associated vasculitis. Since there was nephropathy and there were negative immunological findings of other diseases, a diagnosis of Goodpasture's syndrome was made. A kidney biopsy was not performed. The rapid positive dynamics from hormonal therapy and the absence of relapses and progression raised doubts about this diagnosis. After the disease, the patient refused to take electronic cigarettes. The anamnesis was again addressed, where there were indications of the abuse of electronic cigarettes, after frequent use of which a detailed clinical picture of the disease appeared, the diagnosis of Goodpasture's syndrome was withdrawn, lung damage was regarded as a manifestation of EVALI.</p></sec><sec><title>Conclusion</title><p>Conclusion. Confirmation of the negative impact of electronic smoking systems is the described clinical case, indicating lung damage in humans and difficulties in the differential diagnosis of EVALI syndrome.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>электронные сигареты</kwd><kwd>легкие</kwd><kwd>EVALI.</kwd></kwd-group><kwd-group xml:lang="en"><kwd>electronic cigarettes</kwd><kwd>lungs</kwd><kwd>EVALI</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Оганов Р.Г. 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