cfpdБюллетень физиологии и патологии дыханияBulletin Physiology and Pathology of Respiration1998-5029Дальневосточный научный центр физиологии и патологии дыхания10.36604/1998-5029-2025-97-160-177cfpd-1282Research ArticleОБЗОРЫREVIEWSРоль бактерий Acinetobacter baumannii в инфекционной патологии (обзор литературы)The role of Acinetobacter baumannii in infectious pathology (literature review)https://orcid.org/0000-0002-7598-7343ГолубеваА. О.GolubevaA. O.

Александра Олеговна Голубева, младший научный сотрудник, лаборатория бактериальных инфекций, Федеральное бюджетное учреждение науки «Хабаровский

680000, г. Хабаровск, ул. Шевченко, д.2

Aleksandra O. Golubeva, Junior Staff Scientist, Laboratory of Bacterial Infections, Federal Budgetary Institution of Science "Khabarovsk Scientific Research Institute of Epidemiology and Microbiology"

2 Shevchenko Str., Khabarovsk, 680000

baclab_hniiem@bk.ruhttps://orcid.org/0000-0002-9197-8519БондаренкоА. П.BondarenkoA. P.

Альбина Павловна Бондаренко, канд. мед. наук, ведущий научный сотрудник, зав. лабораторией бактериальных и

680000, г. Хабаровск, ул. Шевченко, д.2

Albina P. Bondarenko, MD, PhD (Med.), Leading Staff Scientist, Head of Laboratory of Bacterial Infections

2 Shevchenko Str., Khabarovsk, 680000

allalab2203@gmail.comhttps://orcid.org/0000-0003-3050-4472ТроценкоO. E.TrotsenkoO. E.

Ольга Евгеньевна Троценко, д-р мед. наук, директор

680000, г. Хабаровск, ул. Шевченко, д.2

Olga E. Trotsenko, MD, PhD, DSc (Med.), Director

2 Shevchenko Str., Khabarovsk, 680000

trotsenko_oe@hniiem.ruhttps://orcid.org/0000-0003-3872-0006ОгиенкоО. Н.OgienkoO. N.

Ольга Николаевна Огиенко, младший научный сотрудник, лаборатория бактериальных инфекций

680000, г. Хабаровск, ул. Шевченко, д.2

Olga N. Ogienko, Junior Staff Scientist, Laboratory of Bacterial Infections

2 Shevchenko Str., Khabarovsk, 680000

baclab_hniiem@bk.ruФедеральное бюджетное учреждение науки «Хабаровский научно-исследовательский институт эпидемиологии и микробиологии» Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человекаFederal Budgetary Institution of Science "Khabarovsk Scientific Research Institute of Epidemiology and Microbiology" of the Federal Service for Supervision of Consumer Rights Protection and Human Well-being202521092025097160177Copyright © Голубева А.О., Бондаренко А.П., Троценко O.E., Огиенко О.Н., 20252025Голубева А.О., Бондаренко А.П., Троценко O.E., Огиенко О.Н.Golubeva A.O., Bondarenko A.P., Trotsenko O.E., Ogienko O.N.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://cfpd.elpub.ru/jour/article/view/1282

Acinetobacter baumannii – один из самых часто инфекционных агентов, выявляемых во всем мире, важными особенностями которых являются высокая частота мутаций, приводящая к быстрому развитию антибиотикорезистентности, и устойчивость к дезинфекции. В данном обзоре представлены сведения о значимости этого патогена в инфекционной патологии, механизмах, лежащих в основе заболеваний, связанных с A. baumannii, факторах вирулентности, множественной лекарственной устойчивости возбудителя, его резистентности к агрессивным факторам внешней среды, приёмах, используемых патогеном для колонизации и заражения организма человека, факторах риска развития инфекции, клинических формах вызываемых им заболеваний. Обсужден выбор препаратов для терапии инфекций, обусловленных A. baumannii. Проведен поиск и анализ отечественных и зарубежных научных публикаций с использованием поисковых систем электронных библиотек – eLIBRARY.ru, Pub-Med, Google Scholar, КиберЛенинка.

Acinetobacter baumannii is one of the most frequently detected infectious agents worldwide, the important features of which are a high mutation rate, leading to the rapid development of antibiotic resistance, and resistance to disinfection. This review presents information on the significance of this pathogen in infectious pathology, the mechanisms underlying diseases associated with A. baumannii, virulence factors, multiple drug resistance of the pathogen, its resistance to aggressive environmental factors, the methods used by the pathogen to colonize and infect the human body, risk factors for infection, and clinical forms of the diseases it causes. The choice of drugs for the treatment of infections caused by A. baumannii is discussed. A search and analysis of scientific publications was carried out using electronic library search systems – eLIBRARY.ru, PubMed, Google Scholar, CyberLeninka

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The authors declare that there are no conflicts of interest present.