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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cfpd</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень физиологии и патологии дыхания</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin Physiology and Pathology of Respiration</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1998-5029</issn><publisher><publisher-name>Дальневосточный научный центр физиологии и патологии дыхания</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.36604/1998-5029-2025-98-150-162</article-id><article-id custom-type="elpub" pub-id-type="custom">cfpd-1305</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Хронический кашель</article-title><trans-title-group xml:lang="en"><trans-title>Chronic cough</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Перельман</surname><given-names>Н. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Perelman</surname><given-names>N. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Наталья Львовна Перельман, д-р мед. наук, ведущий научный сотрудник, лаборатория молекулярных и трансляционных исследований</p><p>675000, г. Благовещенск, ул. Калинина, 22</p></bio><bio xml:lang="en"><p>Natalia L. Perelman, MD, PhD, DSc (Med.), Leading Staff Scientist, Laboratory of Molecular and Translational Research</p><p>22 Kalinina Str., Blagoveshchensk, 675000</p></bio><email xlink:type="simple">lvovna63@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное научное учреждение «Дальневосточный научный центр физиологии и патологии дыхания»</institution></aff><aff xml:lang="en"><institution>Far Eastern Scientific Center of Physiology and Pathology of Respiration</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>23</day><month>12</month><year>2025</year></pub-date><volume>0</volume><issue>98</issue><fpage>150</fpage><lpage>162</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Перельман Н.Л., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Перельман Н.Л.</copyright-holder><copyright-holder xml:lang="en">Perelman N.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cfpd.elpub.ru/jour/article/view/1305">https://cfpd.elpub.ru/jour/article/view/1305</self-uri><abstract><p>В обзоре систематизированы данные научной литературы последних лет, посвященные проблеме хронического кашля. Приведены современные сведения о номенклатуре, эпидемиологии, патологической физиологии хронического кашля. Обсужден ряд фенотипов данного синдрома, особенности его проявлений при различных видах соматической патологии. Акцентировано внимание на рефрактерном варианте хронического кашля, имеющем нейрогенное происхождение, связанное с гиперчувствительностью к кашлевому рефлексу. Описаны особенности хронического кашля у детей и гендерные различия. Освещены изменения качества жизни и социальные аспекты хронического кашля. Приведен инструментарий для оценки качества жизни, связанного с кашлем.</p></abstract><trans-abstract xml:lang="en"><p>The review systematizes the data of the scientific literature of recent years devoted to the problem of chronic cough. It provides modern information on the nomenclature, epidemiology, pathophysiology of chronic cough. A number of phenotypes of this syndrome, the features of its manifestations in various types of somatic pathology are discussed. Attention is focused on the refractory variant of chronic cough, which has a neurogenic origin associated with hypersensitivity to the cough reflex. The features of chronic cough in children and gender differences are described. Changes in the quality of life and social aspects of chronic cough are highlighted. A toolkit for assessing the quality of life associated with cough is provided.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хронический кашель</kwd><kwd>кашлевая гиперчувствительность</kwd><kwd>взрослые</kwd><kwd>дети</kwd><kwd>ятрогенный кашель</kwd><kwd>качество жизни</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic cough</kwd><kwd>cough hypersensitivity</kwd><kwd>adults</kwd><kwd>children</kwd><kwd>iatrogenic cough</kwd><kwd>quality of life</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Зайцев А.А., Будневский А.В., Бродская О.Н. 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