cfpdБюллетень физиологии и патологии дыханияBulletin Physiology and Pathology of Respiration1998-5029Дальневосточный научный центр физиологии и патологии дыхания10.36604/1998-5029-2019-74-111-118cfpd-249Research ArticleОБЗОРЫREVIEWSРОЛЬ ФАКТОРОВ РОСТА В ИНВАЗИИ ТРОФОБЛАСТА И ИХ АССОЦИАЦИЯ С ПАТОЛОГИЧЕСКИМ ТЕЧЕНИЕМ БЕРЕМЕННОСТИTHE ROLE OF GROWTH FACTORS IN TROPHOBLAST INVASION AND THEIR ASSOCIATION WITH THE PATHOLOGICAL COURSE OF PREGNANCYПриходькоН. Г.PrikhodkoN. G.

аспирант, лаборатория механизмов этиопатогенеза и восстановительных процессов дыхательной системы при неспецифических заболеваниях легких

675000, г. Благовещенск, ул. Калинина, 22

MD, Postgraduate Student, Laboratory of Mechanisms of Etiopathogenesis and Recovery Processes of the Respiratory System at Non-Specific Lung Diseases

22 Kalinina Str., Blagoveshchensk, 675000, Russian Federation

nikprih@mail.ruФедеральное государственное бюджетное научное учреждение «Дальневосточный научный центр физиологии и патологии дыхания»Far Eastern Scientific Center of Physiology and Pathology of Respiration201931122019074111118Copyright © Приходько Н.Г., 20192019Приходько Н.Г.Prikhodko N.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://cfpd.elpub.ru/jour/article/view/249фактор роста эндотелия сосудовплацентарный фактор ростатрансформирующий фактор ростаинсулиноподобный фактор ростаинвазия трофобластабеременностьvascular endothelial growth factorplacental growth factortransforming growth factorinsulin-like growth factortrophoblast invasionpregnancyReferencesБоташева Т.Л., Линде В.А., Саргсян О.Д., Ермолова Н.В., Гимбут В.С., Железнякова Е.В., Михельсон А.А. 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Reprod. 2009; 24(1):185–197. doi:10.1093/humrep/den296Prosler J., Chen Q., Chamley L., James J.L. The relationship between TGFbeta, low oxygen and the outgrowth of extravillous trophoblasts from anchoring villi during the first trimestr of pregnancy. Cytokine 2014; 68(1):9–15. doi:10.1016/j.cyto.2014.03.001Prosler J., Chen Q., Chamley L., James J.L. The relationship between TGFbeta, low oxygen and the outgrowth of extravillous trophoblasts from anchoring villi during the first trimestr of pregnancy. Cytokine 2014; 68(1):9–15. doi:10.1016/j.cyto.2014.03.001Prosler J., Chen Q., Chamley L., James J.L. The relationship between TGFbeta, low oxygen and the outgrowth of extravillous trophoblasts from anchoring villi during the first trimestr of pregnancy. Cytokine 2014; 68(1):9–15. doi:10.1016/j.cyto.2014.03.001Prosler J., Chen Q., Chamley L., James J.L. The relationship between TGFbeta, low oxygen and the outgrowth of extravillous trophoblasts from anchoring villi during the first trimestr of pregnancy. Cytokine 2014; 68(1):9–15. doi:10.1016/j.cyto.2014.03.001Sahu M.B., Deepak V., Gonzales S.K., Rimawi B., Watkins K.K., Smith A.K., Badell M.L., Sidell N., Rajakumar A. Decidual cells from women with preeclampsia exhibit inadequate decidualization and reduced sFlt1 suppression. Pregnancy Hypertens. 2019; 15:64–71. doi:10.1016/j.preghy.2018.11.003Sahu M.B., Deepak V., Gonzales S.K., Rimawi B., Watkins K.K., Smith A.K., Badell M.L., Sidell N., Rajakumar A. Decidual cells from women with preeclampsia exhibit inadequate decidualization and reduced sFlt1 suppression. Pregnancy Hypertens. 2019; 15:64–71. doi:10.1016/j.preghy.2018.11.003Sahu M.B., Deepak V., Gonzales S.K., Rimawi B., Watkins K.K., Smith A.K., Badell M.L., Sidell N., Rajakumar A. Decidual cells from women with preeclampsia exhibit inadequate decidualization and reduced sFlt1 suppression. Pregnancy Hypertens. 2019; 15:64–71. doi:10.1016/j.preghy.2018.11.003Sahu M.B., Deepak V., Gonzales S.K., Rimawi B., Watkins K.K., Smith A.K., Badell M.L., Sidell N., Rajakumar A. Decidual cells from women with preeclampsia exhibit inadequate decidualization and reduced sFlt1 suppression. Pregnancy Hypertens. 2019; 15:64–71. doi:10.1016/j.preghy.2018.11.003Shchyogolev A.L., Dubova E.A., Pavlova K.A., Lyapin V.M., Sukhikh G.T. Expression of antiangiogenic factors in the placental structures in pre-eclampsia. Bull. Exp. Biol. Med. 2012; 154(2):287–291. doi:10.1007/s10517-012-1932-0Shchyogolev A.L., Dubova E.A., Pavlova K.A., Lyapin V.M., Sukhikh G.T. Expression of antiangiogenic factors in the placental structures in pre-eclampsia. Bull. Exp. Biol. Med. 2012; 154(2):287–291. doi:10.1007/s10517-012-1932-0Shchyogolev A.L., Dubova E.A., Pavlova K.A., Lyapin V.M., Sukhikh G.T. Expression of antiangiogenic factors in the placental structures in pre-eclampsia. Bull. Exp. Biol. Med. 2012; 154(2):287–291. doi:10.1007/s10517-012-1932-0Shchyogolev A.L., Dubova E.A., Pavlova K.A., Lyapin V.M., Sukhikh G.T. Expression of antiangiogenic factors in the placental structures in pre-eclampsia. Bull. Exp. Biol. Med. 2012; 154(2):287–291. doi:10.1007/s10517-012-1932-0Su M.T., Lin S.H., Chen Y.C. Genetic association studies of angiogenesis and vasoconstriction-related genes in women with recurrent pregnancy loss: a systematic review and meta-analysis. Hum. Reprod. Update 2011; 17(6):803–812. doi:10.1093/humupd/dmr027Su M.T., Lin S.H., Chen Y.C. Genetic association studies of angiogenesis and vasoconstriction-related genes in women with recurrent pregnancy loss: a systematic review and meta-analysis. Hum. Reprod. Update 2011; 17(6):803–812. doi:10.1093/humupd/dmr027Su M.T., Lin S.H., Chen Y.C. Genetic association studies of angiogenesis and vasoconstriction-related genes in women with recurrent pregnancy loss: a systematic review and meta-analysis. Hum. Reprod. Update 2011; 17(6):803–812. doi:10.1093/humupd/dmr027Su M.T., Lin S.H., Chen Y.C. Genetic association studies of angiogenesis and vasoconstriction-related genes in women with recurrent pregnancy loss: a systematic review and meta-analysis. Hum. Reprod. Update 2011; 17(6):803–812. doi:10.1093/humupd/dmr027Venkata Surekha M., Singh S., Sarada K., Sailaja G., Balakrishna N., Srinivas M., Uday Kumar P. Study on the effect of severity of maternal iron deficiency anemia on regulators of angiogenesis in placenta. Fetal Pediatr. Pathol. 2019; 38(5):361–375. doi:10.1080/15513815.2019.1587120Venkata Surekha M., Singh S., Sarada K., Sailaja G., Balakrishna N., Srinivas M., Uday Kumar P. Study on the effect of severity of maternal iron deficiency anemia on regulators of angiogenesis in placenta. Fetal Pediatr. Pathol. 2019; 38(5):361–375. doi:10.1080/15513815.2019.1587120Venkata Surekha M., Singh S., Sarada K., Sailaja G., Balakrishna N., Srinivas M., Uday Kumar P. Study on the effect of severity of maternal iron deficiency anemia on regulators of angiogenesis in placenta. Fetal Pediatr. Pathol. 2019; 38(5):361–375. doi:10.1080/15513815.2019.1587120Venkata Surekha M., Singh S., Sarada K., Sailaja G., Balakrishna N., Srinivas M., Uday Kumar P. Study on the effect of severity of maternal iron deficiency anemia on regulators of angiogenesis in placenta. Fetal Pediatr. Pathol. 2019; 38(5):361–375. doi:10.1080/15513815.2019.1587120Visan V., Scripcariu I.S., Socolov D., Costescu A., Rusu D., Socolov R., Avasiloaiei A., Boiculese L., Dimitriu C. Better prediction for FGR (fetal growth restriction) with the sFlt-1/PIGF ratio: A case-control study. Medicine (Baltimore) 2019; 98(26):e16069. doi:10.1097/MD.0000000000016069Visan V., Scripcariu I.S., Socolov D., Costescu A., Rusu D., Socolov R., Avasiloaiei A., Boiculese L., Dimitriu C. Better prediction for FGR (fetal growth restriction) with the sFlt-1/PIGF ratio: A case-control study. Medicine (Baltimore) 2019; 98(26):e16069. doi:10.1097/MD.0000000000016069Visan V., Scripcariu I.S., Socolov D., Costescu A., Rusu D., Socolov R., Avasiloaiei A., Boiculese L., Dimitriu C. Better prediction for FGR (fetal growth restriction) with the sFlt-1/PIGF ratio: A case-control study. Medicine (Baltimore) 2019; 98(26):e16069. doi:10.1097/MD.0000000000016069Visan V., Scripcariu I.S., Socolov D., Costescu A., Rusu D., Socolov R., Avasiloaiei A., Boiculese L., Dimitriu C. Better prediction for FGR (fetal growth restriction) with the sFlt-1/PIGF ratio: A case-control study. Medicine (Baltimore) 2019; 98(26):e16069. doi:10.1097/MD.0000000000016069Wang P., Fan J., Chen Z., Meng Z.Q., Meng Z.Q., Luo J.M., Lin J.H., Zhou Z.H., Chen H., Wang K., Xu Z.D., Liu L.M. Low-level expression of Smad7 correlates with lymph node metastasis and poor prognosis in patients with pancreatic cancer. Ann. Surg. Oncol. 2009; 16(4):826–835. doi:10.1245/s10434-008-0284-5Wang P., Fan J., Chen Z., Meng Z.Q., Meng Z.Q., Luo J.M., Lin J.H., Zhou Z.H., Chen H., Wang K., Xu Z.D., Liu L.M. Low-level expression of Smad7 correlates with lymph node metastasis and poor prognosis in patients with pancreatic cancer. Ann. Surg. Oncol. 2009; 16(4):826–835. doi:10.1245/s10434-008-0284-5Wang P., Fan J., Chen Z., Meng Z.Q., Meng Z.Q., Luo J.M., Lin J.H., Zhou Z.H., Chen H., Wang K., Xu Z.D., Liu L.M. Low-level expression of Smad7 correlates with lymph node metastasis and poor prognosis in patients with pancreatic cancer. Ann. Surg. Oncol. 2009; 16(4):826–835. doi:10.1245/s10434-008-0284-5Wang P., Fan J., Chen Z., Meng Z.Q., Meng Z.Q., Luo J.M., Lin J.H., Zhou Z.H., Chen H., Wang K., Xu Z.D., Liu L.M. Low-level expression of Smad7 correlates with lymph node metastasis and poor prognosis in patients with pancreatic cancer. Ann. Surg. Oncol. 2009; 16(4):826–835. doi:10.1245/s10434-008-0284-5

The authors declare that there are no conflicts of interest present.