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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cfpd</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень физиологии и патологии дыхания</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin Physiology and Pathology of Respiration</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1998-5029</issn><publisher><publisher-name>Дальневосточный научный центр физиологии и патологии дыхания</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">cfpd-294</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>ОЦЕНКА ИНТЕНСИВНОСТИ ГАЗООБМЕНА В МИКРОСТРУКТУРАХ ЛЕГОЧНОГО АЦИНУСА С ИСПОЛЬЗОВАНИЕМ АНАЛИТИЧЕСКОГО МОДЕЛИРОВАНИЯ</article-title><trans-title-group xml:lang="en"><trans-title>RATING OF INTENSITY OF GAS EXCHANGE IN MICROSTRUCTURES OF LUNG ACINUS WITH USE OF ANALYTICAL MODELLING</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шишкин</surname><given-names>Геннадий Сергеевич</given-names></name><name name-style="western" xml:lang="en"><surname>Shishkin</surname><given-names>G. S.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Устюжанинова</surname><given-names>Нина Витальевна</given-names></name><name name-style="western" xml:lang="en"><surname>Ustyzhaninova</surname><given-names>N. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гладырь</surname><given-names>Сергей Николаевич</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>НИИ физиологии СО РАМН</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2007</year></pub-date><pub-date pub-type="epub"><day>18</day><month>02</month><year>2020</year></pub-date><volume>0</volume><issue>26</issue><fpage>7</fpage><lpage>12</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шишкин Г.С., Устюжанинова Н.В., Гладырь С.Н., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Шишкин Г.С., Устюжанинова Н.В., Гладырь С.Н.</copyright-holder><copyright-holder xml:lang="en">Shishkin G.S., Ustyzhaninova N.V., Гладырь С.Н.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cfpd.elpub.ru/jour/article/view/294">https://cfpd.elpub.ru/jour/article/view/294</self-uri><abstract><p>Аналитическое моделирование газообмена в микроструктурах ацинуса показало, что в функциональном отношении он не однороден. Альвеолы, альвеолярные мешки и альвеолярные ходы 3-го порядка образуют зону стабильного газообмена, составляющую 72-86% объема ацинуса (респираторная зона), а 4-го порядка респираторных бронхиол и альвеолярные ходы 1-го и частично 2-го порядков относятся к зоне нестабильного газообмена (транзиторная зона). Определены объемы зон, их участие в газообмене и зависимость от массы тела. Установлен градиент концентрации двуокиси углерода в ацинусе от терминальной бронхиолы до терминальных альвеол. Показано наличие симморфоза в легких человека, проявляющегося в газообменных структурах транзиторной зоны.</p></abstract><trans-abstract xml:lang="en"><p>Analytical modelling of gas exchange in microstructures of acinus has shown, that functionally it is not homogeneous. Alveolus, alveolar bags and alveolar courses of 3-rd order formates a zone of stable gas exchange, a component of 72-86% of acinus volume (a respiratory zone), and 4 order of respiratory bronchiolus and alveolar courses of 1-st and in part 2-nd orders relate to a zone of astable gas exchange (transit zone). Volumes of zones, their participation in gas exchange and dependence on weight of a body are determined. The gradient of concentration of carbon dioxide in acinus from terminal bronchiolus up to terminal alveolus is established. Presence of symmorphosis in human lungs, which occurs in gas exchange structures of transit zone is shown.</p></trans-abstract></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Морфометрия легких человека [Текст]/Э.Р.Вейбель.-М.: Медицина,1970.-175 с.</mixed-citation><mixed-citation xml:lang="en">Морфометрия легких человека [Текст]/Э.Р.Вейбель.-М.: Медицина,1970.-175 с.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Структурная организация легочной дольки [Текст]/Шишкин Г.С. [и др.]//Морфология.-1999.-Т.1, №4.-С.45-48.</mixed-citation><mixed-citation xml:lang="en">Структурная организация легочной дольки [Текст]/Шишкин Г.С. 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