cfpdБюллетень физиологии и патологии дыханияBulletin Physiology and Pathology of Respiration1998-5029Дальневосточный научный центр физиологии и патологии дыханияcfpd-329Research ArticleСтатьиРОЛЬ КОМПЬЮТЕРНОЙ ТОМОГРАФИИ В ДИАГНОСТИКЕ ИЗМЕНЕНИЙ РЕГИОНАРНОЙ ВЕНТИЛЯЦИОННОЙ ФУНКЦИИ ЛЕГКИХ И РЕАКТИВНОСТИ ДЫХАТЕЛЬНЫХ ПУТЕЙ У БОЛЬНЫХ БРОНХИАЛЬНОЙ АСТМОЙTHE ROLE OF COMPUTED TOMOGRAPHY IN THE DIAGNOSIS OF CHANGES IN LUNG REGIONAL VENTILATION AND AIRWAY REACTIVITY IN PATIENTS WITH BRONCHIAL ASTHMAГребенникАнтон ГригорьевичGrebennikA. G.noemail@neicon.ruДальневосточный научный центр физиологии и патологии дыхания Сибирского отделения РАМНRussian Federation2007180220200266368Copyright © Гребенник А.Г., 20202020Гребенник А.Г.Grebennik A.G.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://cfpd.elpub.ru/jour/article/view/329

Представлен обзор отечественных и зарубежных литературных данных о регионарной вентиляционной функции легких и реактивности дыхательных путей у больных бронхиальной астмой. Описана роль различных методов компьютерно-томографической диагностики.

The paper reviews Russian and foreign literature data on regional lung ventilation function and airway reactivity in patients with bronchial asthma. The role of various computed tomography diagnostic techniques has also been described.

ReferencesСпиральная компьютерная томография с функциональными пробами в диагностике хронических обструктивныхболезней легких [Текст]/Васильев А.Ю. [и др.]//Клиническая медицина.-2003.- №8.-С.29-31.Спиральная компьютерная томография с функциональными пробами в диагностике хронических обструктивныхболезней легких [Текст]/Васильев А.Ю. [и др.]//Клиническая медицина.-2003.- №8.-С.29-31.Глобальная стратегия диагностики, лечения и профилактики бронхиальной астмы. Пересмотр 2002 [Текст]/под редакцией А.Г.Чучалина.-М.: Атмосфера, 2002.-160 с.Глобальная стратегия диагностики, лечения и профилактики бронхиальной астмы. Пересмотр 2002 [Текст]/под редакцией А.Г.Чучалина.-М.: Атмосфера, 2002.-160 с.Хроническая обструктивная болезнь легких: распространенность и смертность [Текст]/И.А.Зарембо//Аллергология.-2006.-№1.-С.39-43.Хроническая обструктивная болезнь легких: распространенность и смертность [Текст]/И.А.Зарембо//Аллергология.-2006.-№1.-С.39-43.Новые технологии и прогресс лучевой диагностики диффузных заболеваний легких [Текст]/ П.М.Котляров, С.Г.Георгиади//Пульмонология.-2005.-№6.-С.61-69.Новые технологии и прогресс лучевой диагностики диффузных заболеваний легких [Текст]/ П.М.Котляров, С.Г.Георгиади//Пульмонология.-2005.-№6.-С.61-69.Разработка и клиническое применение методов рентгенофункционального исследования легких [Текст]/А.В.Леншин//Бюл. физиол. и патол. дыхания.-2004.-Вып.16.-С.6-11.Разработка и клиническое применение методов рентгенофункционального исследования легких [Текст]/А.В.Леншин//Бюл. физиол. и патол. дыхания.-2004.-Вып.16.-С.6-11.Клиническое обоснование методов этапной диагностики регионарной вентиляции легких при заболеваниях органов дыхания [Текст]/А.В.Леншин: автореф. дис. … д-ра мед. наук.-Благовещенск, 2004.-38 с.Клиническое обоснование методов этапной диагностики регионарной вентиляции легких при заболеваниях органов дыхания [Текст]/А.В.Леншин: автореф. дис. … д-ра мед. наук.-Благовещенск, 2004.-38 с.Этиопатогенетические аспекты бронхиальной астмы в Дальневосточном регионе [Текст]/М.Т.Луценко, Б.Е.Бабцев//Бюл. физиол. и патол. дыхания.-1999.-Вып.4.-С.6-11.Этиопатогенетические аспекты бронхиальной астмы в Дальневосточном регионе [Текст]/М.Т.Луценко, Б.Е.Бабцев//Бюл. физиол. и патол. дыхания.-1999.-Вып.4.-С.6-11.Распространенность бронхиальной астмы [Текст]/Лютина Е.И. [и др.]//Здравоохранение РФ.-2004.-№2.-С.35-37.Распространенность бронхиальной астмы [Текст]/Лютина Е.И. [и др.]//Здравоохранение РФ.-2004.-№2.-С.35-37.Инспираторно-экспираторная компьютерная томография высокого разрешения в диагностике хронической обструктивной болезни легких [Текст]/О.В.Родионова: автореф. дис. … канд. мед. наук.-Томск, 2005.-27 с.Инспираторно-экспираторная компьютерная томография высокого разрешения в диагностике хронической обструктивной болезни легких [Текст]/О.В.Родионова: автореф. дис. … канд. мед. наук.-Томск, 2005.-27 с.Инспираторно-экспираторная HRCT в диагностике обструктивного синдрома легких [Текст]/Родионова О.В. [и др.]//Невский радиологический форум "Из будущего в настоящее".-СПб., 2003.-С.140-141.Инспираторно-экспираторная HRCT в диагностике обструктивного синдрома легких [Текст]/Родионова О.В. [и др.]//Невский радиологический форум "Из будущего в настоящее".-СПб., 2003.-С.140-141.Новые технологии лучевой диагностики [Текст]/С.Терновой, В.Синицын//Врач.-2005.-№4.-С.28-32.Новые технологии лучевой диагностики [Текст]/С.Терновой, В.Синицын//Врач.-2005.-№4.-С.28-32.Актуальные вопросы пульмонологии [Текст]/А.Г.Чучалин//Русский мед. журнал.-2000.-Т.8, №17.-С.727-730.Актуальные вопросы пульмонологии [Текст]/А.Г.Чучалин//Русский мед. журнал.-2000.-Т.8, №17.-С.727-730.Тяжелые формы бронхиальной астмы [Текст]/А.Г.Чучалин//Тер. архив.-2000.-№17.-С.5-9.Тяжелые формы бронхиальной астмы [Текст]/А.Г.Чучалин//Тер. архив.-2000.-№17.-С.5-9.Air trapping on expiratory high-resolution CT scans in the absence of inspiratory scan abnormalities: correlation with pulmonary function tests and differential diagnosis [Text]/H.Arakawa, W.R.Webb//Am. J. Radiol.-1998.-Vol.170.-P.1349–1353.Air trapping on expiratory high-resolution CT scans in the absence of inspiratory scan abnormalities: correlation with pulmonary function tests and differential diagnosis [Text]/H.Arakawa, W.R.Webb//Am. J. Radiol.-1998.-Vol.170.-P.1349–1353.Mild intermittent asthma: CT assessment of bronchial cross-sectional area and lung attenuation at controlled lung volume [Text]/Beigelman-Aubry C. [et al.]//Radiology.-2002.-Vol.223.-P.181–187.Mild intermittent asthma: CT assessment of bronchial cross-sectional area and lung attenuation at controlled lung volume [Text]/Beigelman-Aubry C. [et al.]//Radiology.-2002.-Vol.223.-P.181–187.Structure and function of small airways in smokers: relationship between Air Trapping at CT and airway inflammation [Text]/Berger P. [et al.]//Radiology.-2003.-Vol.228.-P.85-94.Structure and function of small airways in smokers: relationship between Air Trapping at CT and airway inflammation [Text]/Berger P. [et al.]//Radiology.-2003.-Vol.228.-P.85-94.High-resolution CT is more sensitive to longitudinal decline in lung status in young children with CF than pulmonary function tests [Text]/A.S.Brody//Pediatr. Pulmonol.-2003.-Vol.36.-P.388.High-resolution CT is more sensitive to longitudinal decline in lung status in young children with CF than pulmonary function tests [Text]/A.S.Brody//Pediatr. Pulmonol.-2003.-Vol.36.-P.388.Spirometrically Gated High-Resolution CT findings in COPD: lung attenuation vs lung function and dyspnea severity [Text]/Camiciottoli G. [et al.]//Chest.-2006.-Vol.129 (3).-P.558-564.Spirometrically Gated High-Resolution CT findings in COPD: lung attenuation vs lung function and dyspnea severity [Text]/Camiciottoli G. [et al.]//Chest.-2006.-Vol.129 (3).-P.558-564.High resolution volume imaging of airways and lung parenchyma with multislice CT [Text]/W.K. Chooi, S.K.Morcos//Br. J. Radiol.-2004.-Vol.77.-P.98-105.High resolution volume imaging of airways and lung parenchyma with multislice CT [Text]/W.K. Chooi, S.K.Morcos//Br. J. Radiol.-2004.-Vol.77.-P.98-105.Tracheobronchial tree: three-dimensional spiral CT with bronchoscopic perspective [Text]/Ferretti G.R. [et al.]//J. Comput. Assist. Tomogr.-1996.-Vol.20.-P.777–781.Tracheobronchial tree: three-dimensional spiral CT with bronchoscopic perspective [Text]/Ferretti G.R. [et al.]//J. Comput. Assist. Tomogr.-1996.-Vol.20.-P.777–781.Patient selection for lung volume reduction surgery: an objective model based on prior clinical de-cisions and quantitative CT analysis [Text]/Gierada D.S. [et al.]//Chest.-2000.-Vol.117.-P.991-998.Patient selection for lung volume reduction surgery: an objective model based on prior clinical de-cisions and quantitative CT analysis [Text]/Gierada D.S. [et al.]//Chest.-2000.-Vol.117.-P.991-998.Evaluation of airway wall thickness and air trapping by HRCT in asymptomatic asthma [Text]/Gono H. [et al.]//Eur. Respir. J.-2003.-Vol.22.-P.965–971.Evaluation of airway wall thickness and air trapping by HRCT in asymptomatic asthma [Text]/Gono H. [et al.]//Eur. Respir. J.-2003.-Vol.22.-P.965–971.Low-dose dynamic expiratory thin-section CT of the lungs using a spiral CT scanner [Text]/Gotway M.B. [et al.]//J. Thorac. Imaging.-2000.-Vol.15.-P.168–172.Low-dose dynamic expiratory thin-section CT of the lungs using a spiral CT scanner [Text]/Gotway M.B. [et al.]//J. Thorac. Imaging.-2000.-Vol.15.-P.168–172.Characterization of the interstitial lung diseases via density-based and texture-based analysis of computed tomography images of lung structure and function [Text]/Hoffman E.A. [et al.]//Acad. Radiol.-2003.-Vol.10.- P.1104–1118.Characterization of the interstitial lung diseases via density-based and texture-based analysis of computed tomography images of lung structure and function [Text]/Hoffman E.A. [et al.]//Acad. Radiol.-2003.-Vol.10.- P.1104–1118.Computed tomographic imaging of the airways: relationship to structure and function [Text]/de Jong P.A. [et al.]//Eur. Respir. J.-2005.-Vol.26.-P.140–152.Computed tomographic imaging of the airways: relationship to structure and function [Text]/de Jong P.A. [et al.]//Eur. Respir. J.-2005.-Vol.26.-P.140–152.Heterogeneity of narrowing in normal and asthmatic airways measured by HRCT [Text]/King G.G. [et al.]//Eur. Respir. J.-2004.-Vol.24.-P.211–218.Heterogeneity of narrowing in normal and asthmatic airways measured by HRCT [Text]/King G.G. [et al.]//Eur. Respir. J.-2004.-Vol.24.-P.211–218.High resolution computed tomographic assessment of airway wall thickness in chronic asthma: reproducibility and relationship with lung function and severity [Text]/Little S.A. [et al.]//Thorax.-2002.- Vol.57.-P.247–253.High resolution computed tomographic assessment of airway wall thickness in chronic asthma: reproducibility and relationship with lung function and severity [Text]/Little S.A. [et al.]//Thorax.-2002.- Vol.57.-P.247–253.Quantitative computed tomography assessment of lung structure and function in pulmonary emphysema [Text]/Madani A. [et al.]//Eur. Respir. J.-2001.-Vol.18 (4).-P.720-730.Quantitative computed tomography assessment of lung structure and function in pulmonary emphysema [Text]/Madani A. [et al.]//Eur. Respir. J.-2001.-Vol.18 (4).-P.720-730.The CT Scan ARDS Study Group. Computed tomography assessment of positive end-expiratory pressure-induced alveolar recruitment in patients with acute respiratory distress syndrome [Text]/Malbouisson L. [et al.]//Am. J. Respir. Crit. Care Med.-2001.-Vol.163.-P.1444-1450.The CT Scan ARDS Study Group. Computed tomography assessment of positive end-expiratory pressure-induced alveolar recruitment in patients with acute respiratory distress syndrome [Text]/Malbouisson L. [et al.]//Am. J. Respir. Crit. Care Med.-2001.-Vol.163.-P.1444-1450.Complexity of terminal airspace geometry assessed by computed tomography in asthma [Text]/Mitsunobu F. [et al.]//Am. J. Respir. Crit. Care Med.-2003.-Vol.167.-P.411–417.Complexity of terminal airspace geometry assessed by computed tomography in asthma [Text]/Mitsunobu F. [et al.]//Am. J. Respir. Crit. Care Med.-2003.-Vol.167.-P.411–417.Quantitative assessment of airway remodeling using high-resolution CT [Text]/Nakano Y. [et al.]//Chest.-2002.-Vol.122.-P.271–275.Quantitative assessment of airway remodeling using high-resolution CT [Text]/Nakano Y. [et al.]//Chest.-2002.-Vol.122.-P.271–275.Computed tomographic measurements of airway dimensions and emphysema in smokers: correlation with lung function [Text]/Nakano Y. [et al.]//Am. J. Respir. Crit. Care Med.-2000.-Vol.162.-P.1102–1108.Computed tomographic measurements of airway dimensions and emphysema in smokers: correlation with lung function [Text]/Nakano Y. [et al.]//Am. J. Respir. Crit. Care Med.-2000.-Vol.162.-P.1102–1108.Physiological and radiological characterisation of patients diagnosed with chronic obstructive pulmonary disease in primary care [Text]/O'Brien C. [et al.]//Thorax.-2000.-Vol.55.-P.635–642.Physiological and radiological characterisation of patients diagnosed with chronic obstructive pulmonary disease in primary care [Text]/O'Brien C. [et al.]//Thorax.-2000.-Vol.55.-P.635–642.Chronic obstructive pulmonary disease: thin-section CT measurement of airway wall thickness and lung attenuation [Text]/Orlandi I. [et al.]//Radiology.-2005.-Vol.234.-P.604–610.Chronic obstructive pulmonary disease: thin-section CT measurement of airway wall thickness and lung attenuation [Text]/Orlandi I. [et al.]//Radiology.-2005.-Vol.234.-P.604–610.High-resolution CT quantification of bronchiectasis: clinical and functional correlation [Text]/Ooi G.C. [et al.]//Radiology.-2002.-Vol.225.-P.663–672.High-resolution CT quantification of bronchiectasis: clinical and functional correlation [Text]/Ooi G.C. [et al.]//Radiology.-2002.-Vol.225.-P.663–672.Using computed tomographic scanning to advance understanding of chronic obstructive pulmonary disease [Text]/ J.Reilly//The Proceedings of the Am. Thorac. Society.-2006.-Vol.3.-P.450-455.Using computed tomographic scanning to advance understanding of chronic obstructive pulmonary disease [Text]/ J.Reilly//The Proceedings of the Am. Thorac. Society.-2006.-Vol.3.-P.450-455.Spirometer-triggered high-resolution computed tomography and pulmonary function measurements during an acute exacerbation in patients with cystic fibrosis [Text]/Robinson T.E. [et al.]//J. Pediatr.-2001.-Vol.138.-P.553–559.Spirometer-triggered high-resolution computed tomography and pulmonary function measurements during an acute exacerbation in patients with cystic fibrosis [Text]/Robinson T.E. [et al.]//J. Pediatr.-2001.-Vol.138.-P.553–559.Asthma and associated conditions: high-resolution CT and pathologic findings [Text]/Silva C.I. [et al.]//Am. J. Roentgenol.-2004.-Vol.183.-P.817–824.Asthma and associated conditions: high-resolution CT and pathologic findings [Text]/Silva C.I. [et al.]//Am. J. Roentgenol.-2004.-Vol.183.-P.817–824.Asthma and COPD [Text]/ T.Welte//Exp. Toxicol. Pathol.-2006.-Vol.57.-P.35-40.Asthma and COPD [Text]/ T.Welte//Exp. Toxicol. Pathol.-2006.-Vol.57.-P.35-40.Paired inspiratory/expiratory volumetric thin-slice CT scan for emphysema analysis: comparison of different quantitative evaluations and pulmonary function test [Text]/Zaporozhan J. [et al.]//Chest.-2005.-Vol.128 (5).-P.3212-3220.Paired inspiratory/expiratory volumetric thin-slice CT scan for emphysema analysis: comparison of different quantitative evaluations and pulmonary function test [Text]/Zaporozhan J. [et al.]//Chest.-2005.-Vol.128 (5).-P.3212-3220.The role of spiral volumetric computed tomography in the diagnosis of pulmonary embolism [Text]/Mullins M.D. [et al.]//Arch. Intern. Med.-2000.-Vol.160.-P.293-298.The role of spiral volumetric computed tomography in the diagnosis of pulmonary embolism [Text]/Mullins M.D. [et al.]//Arch. Intern. Med.-2000.-Vol.160.-P.293-298.

The authors declare that there are no conflicts of interest present.