cfpdБюллетень физиологии и патологии дыханияBulletin Physiology and Pathology of Respiration1998-5029Дальневосточный научный центр физиологии и патологии дыханияcfpd-405Research ArticleСтатьиАктивность ганглиозидов в тканях легких при общем охлаждении организмаActivity of gangliosides in lungs at general cooling of organismЛуценкоМихаил ТимофеевичLutsenkoMikhail T.Lucenkomt@mail.ru <mailto:Lucenkomt@mail.ru>Дальневосточный научный центр физиологии и патологии дыхания Сибирского отделения РАМН, БлаговещенскFar Eastern Science Centre Physiology And Pathology Of Respiration2011190220200412830Copyright &#x00A9; Луценко М.Т., 20202020Луценко М.Т.Lutsenko M.T.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://cfpd.elpub.ru/jour/article/view/405

Изучено содержание ганглиозидов в легких при общем охлаждении организма кроликов. Охлаждение вызывает увеличение полисиаловых ганглиозидов GT1B, GD2 и GD3 и снижение концентрации моносиаловых ганглиозидов GМ2, GМ3, GD1A, что может быть связано с активизацией синтетазы GT1В и ингибированием нейраминидазы, отщепляющей сиаловые кислоты от углеводной цепи.

The contents of gangliosides in lungs at general cooling of rabbits' organism have been studied. The cooling induces the increase of polysialic gangliosides GT1B, GD2 and GD3 and the decrease of concentration of monosialic gangliosides GМ2, GМ3, GD1A, which may be connected with activation of synthetase GT1В and inhibition of neuraminidase that disconnects sialic acids from a carbohydrate chain.

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The authors declare that there are no conflicts of interest present.