<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cfpd</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень физиологии и патологии дыхания</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin Physiology and Pathology of Respiration</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1998-5029</issn><publisher><publisher-name>Дальневосточный научный центр физиологии и патологии дыхания</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">cfpd-674</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>ТРОМБОЭМБОЛИЯ ЛЕГОЧНЫХ АРТЕРИЙ В КЛИНИЧЕСКОЙ ПРАКТИКЕ</article-title><trans-title-group xml:lang="en"><trans-title>THROMBOEMBOLISM OF PULMONARY ARTERIES IN CLINICAL PRACTICE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сахарюк</surname><given-names>Александр Петрович</given-names></name><name name-style="western" xml:lang="en"><surname>Sakharyuk</surname><given-names>Aleksandr P.</given-names></name></name-alternatives><email xlink:type="simple">fyubj@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шимко</surname><given-names>Владимир Васильевич</given-names></name><name name-style="western" xml:lang="en"><surname>Shimko</surname><given-names>Vladimir V.</given-names></name></name-alternatives><email xlink:type="simple">amurgma@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тарасюк</surname><given-names>Евгений Сергеевич</given-names></name><name name-style="western" xml:lang="en"><surname>Tarasyuk</surname><given-names>Evgeniy S.</given-names></name></name-alternatives><email xlink:type="simple">amurgma@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вереветинов</surname><given-names>Артем Николаевич</given-names></name><name name-style="western" xml:lang="en"><surname>Verevetinov</surname><given-names>Artem N.</given-names></name></name-alternatives><email xlink:type="simple">amurgma@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Раповка</surname><given-names>Виктор Григорьевич</given-names></name><name name-style="western" xml:lang="en"><surname>Rapovka</surname><given-names>Viktor G.</given-names></name></name-alternatives><email xlink:type="simple">primvasc@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Вавринчук</surname><given-names>Сергей Андреевич</given-names></name><name name-style="western" xml:lang="en"><surname>Vavrinchuk</surname><given-names>Sergey A.</given-names></name></name-alternatives><email xlink:type="simple">rec@ipksz.khv.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Емец</surname><given-names>Александр Николаевич</given-names></name><name name-style="western" xml:lang="en"><surname>Emets</surname><given-names>Aleksandr N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Амурская государственная медицинская академия</institution></aff><aff xml:lang="en"><institution>Amur State Medical Academy</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Тихоокеанский государственный медицинский университет</institution></aff><aff xml:lang="en"><institution>Pacific State Medical University</institution></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Институт повышения квалификации сотрудников здравоохранения Хабаровского края</institution></aff><aff xml:lang="en"><institution>Postgraduate Institute for Public Health Workers</institution></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Городская клиническая больница</institution></aff><aff xml:lang="en"><institution>Blagoveshchensk City Clinical Hospital</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>20</day><month>02</month><year>2020</year></pub-date><volume>0</volume><issue>55</issue><fpage>48</fpage><lpage>53</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сахарюк А.П., Шимко В.В., Тарасюк Е.С., Вереветинов А.Н., Раповка В.Г., Вавринчук С.А., Емец А.Н., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Сахарюк А.П., Шимко В.В., Тарасюк Е.С., Вереветинов А.Н., Раповка В.Г., Вавринчук С.А., Емец А.Н.</copyright-holder><copyright-holder xml:lang="en">Sakharyuk A.P., Shimko V.V., Tarasyuk E.S., Verevetinov A.N., Rapovka V.G., Vavrinchuk S.A., Emets A.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cfpd.elpub.ru/jour/article/view/674">https://cfpd.elpub.ru/jour/article/view/674</self-uri><abstract><p>Произведено изучение летальности от венозных тромбоэмболических осложнений за три года по результатам патологоанатомических исследований 1764 пациентов. При исследовании учитывали возраст, пол, время года, основное заболевание, по поводу которого пациент находился в стационаре, сроки смерти с момента поступления в стационар, источник первичного тромбообразования, изменения в легочной ткани, уровень обтурации легочного венозного русла эмбологенными массами. Установлено, что у 5,4% больных причиной смерти явились венозные тромбоэмболические осложнения - 0,8 на 1000 населения в год. Средний возраст пациентов, погибших от тромбоэмболии легочной артерии - 58 лет, по половому признаку преобладали женщины - 58%. Структура патологии, по поводу которой пациенты получали стационарное лечение: послеоперационный период после многопрофильных хирургических вмешательств - 31%, острые нарушения мозгового кровообращения - 32%, многопрофильная терапевтическая патология - 37%. У 20% смерть наступила от массивной тромбоэмболии легочной артерии в первые сутки с момента поступления, 25% погибли через 2-7 дней, 57% - от 7 дней до нескольких месяцев. Источником первичного тромбообразования у 52% пациентов явились венозные синусы голени, у 22% - подколенно-бедренно-подвздошный сегмент и нижняя полая вена, у 10% - правые отделы сердца, у 16% пациентов источник не обнаружен. У 2/3 больных имелась острая обтурация легочного ствола и главных ветвей легочной артерии. Разработаны способы предупреждения развития венозных тромбоэмболических осложнений и массивной тромбоэмболии легочной артерии у стационарных больных Амурской области.</p></abstract><trans-abstract xml:lang="en"><p>The study of lethality from venous thrombo-embolic complications was done for three years by the results of pathological-anatomical examinations of 1764 patients. Age, sex, the season of the year, the main disease because of which the patient was in hospital, the dates of death since the moment of the patient getting to hospital, the sources of the initial thrombi formation, the changes in the pulmonary tissue, the level of obturation of pulmonary venous bed by embologenic masses were considered. It was found out that in 5.4% of the patients the cause of the death was venous thrombo-embolic complications: 0.8 per 1000 of population a year. The mean age of patients who died from thromboembolism of pulmonary artery is 58 years, by the sex parameter women dominated (58%). The structure of pathology because of which patients had the treatment in hospital is the following: postoperative period after multiprofile surgeries (31%), severe disorders of brain blood circulation (32%), multiprofile therapeutic pathology (37%). 20% of patients died from massive thromboembolism of pulmonary artery at the first day after it happened, 25% died in 2-7 days, 57% died at the 7th day or in several months. The source of the first thrombi formation in 52% of patients became venous sinuses of anticnemion, in 22% it was popliteus-thigh-iliac segment and low cava, in 10% these were the right compartments of heart, in 16% the source was not identified. In 2/3 of patients there was an acute obturation of the pulmonary trunk and of main branches of the pulmonary artery. The ways of prevention of the formation of venous thromboembolic complications and massive thromboembolism of the pulmonary artery in hospital patients of the Amur region were developed</p></trans-abstract><kwd-group xml:lang="ru"><kwd>венозный тромбоз</kwd><kwd>венозные тромбоэмболические осложнения</kwd><kwd>тромбоэмболия легочных артерий</kwd><kwd>venous thrombosis</kwd><kwd>venous thromboembolic complications</kwd><kwd>thromboembolism of pulmonary artery</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Сравнительная оценка методов кавафильтрации при эмбологенных флеботромбозах / Н.А.Гордеев [и др.] // Вестн. хир. им. И.И.Грекова. 1991. Т.146, №4. С.40-44.</mixed-citation><mixed-citation xml:lang="en">Сравнительная оценка методов кавафильтрации при эмбологенных флеботромбозах / Н.А.Гордеев [и др.] // Вестн. хир. им. И.И.Грекова. 1991. Т.146, №4. С.40-44.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Эмболическая окклюзия нижней полой вены после имплантации кава-фильтра / В.Н.Ильин [и др.] // Хирургия. 1984. №10. С.46-49.</mixed-citation><mixed-citation xml:lang="en">Эмболическая окклюзия нижней полой вены после имплантации кава-фильтра / В.Н.Ильин [и др.] // Хирургия. 1984. №10. С.46-49.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Савельев B.C., Матюшенко А.А. Тромбоэмболия легочных артерий. Точка зрения хирурга // Грудная и сердечно-сосудистая хирургия. 1999. №6. С.6-11.</mixed-citation><mixed-citation xml:lang="en">Савельев B.C., Матюшенко А.А. Тромбоэмболия легочных артерий. Точка зрения хирурга // Грудная и сердечно-сосудистая хирургия. 1999. №6. С.6-11.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Мультицентровое исследование препарата Детралекс (Relief study). Обобщенные результаты Российской части проекта / B.C.Савельев [и др.] // Междунар. мед. журн. 2000. №5. С.398-402.</mixed-citation><mixed-citation xml:lang="en">Мультицентровое исследование препарата Детралекс (Relief study). Обобщенные результаты Российской части проекта / B.C.Савельев [и др.] // Междунар. мед. журн. 2000. №5. С.398-402.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Туляганов П.Д., Степанов В.А. Тромбоэмболия легочной артерии в многопрофильном стационаре // Мед. журн. Узбекистана. 1983. №3. С.48-51.</mixed-citation><mixed-citation xml:lang="en">Туляганов П.Д., Степанов В.А. Тромбоэмболия легочной артерии в многопрофильном стационаре // Мед. журн. Узбекистана. 1983. №3. С.48-51.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Случай сочетанного илеофеморального и внутрисердечного тромбоза при антифосфолипидном синдроме / А.С.Ярыгин [и др.] // Грудная и сердечно сосудистая хирургия. 2003. №5. С.76-78.</mixed-citation><mixed-citation xml:lang="en">Случай сочетанного илеофеморального и внутрисердечного тромбоза при антифосфолипидном синдроме / А.С.Ярыгин [и др.] // Грудная и сердечно сосудистая хирургия. 2003. №5. С.76-78.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Ansari A. Acute and chronic pulmonary thromboembolism: current perspectives. Part. 6. Course and prognosis and natural history // Clin. Cardiol. 1987. Vol.10, №1. P.40-43.</mixed-citation><mixed-citation xml:lang="en">Ansari A. Acute and chronic pulmonary thromboembolism: current perspectives. Part. 6. Course and prognosis and natural history // Clin. Cardiol. 1987. Vol.10, №1. P.40-43.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">«Counterintuitive» preferences in health-related quality-of-life measurement / J.W.Bush [et al.] // Med. Care. 1982. Vol.20. №5. P.516-525.</mixed-citation><mixed-citation xml:lang="en">«Counterintuitive» preferences in health-related quality-of-life measurement / J.W.Bush [et al.] // Med. Care. 1982. Vol.20. №5. P.516-525.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Suprarenal Greenfield filter placement to prevent pulmonary embolus in patients with vena caval tumor thrombi / D.W.Brenner [et. al.] // J. Urol. 1992. Vol.147, №1. P.19-23.</mixed-citation><mixed-citation xml:lang="en">Suprarenal Greenfield filter placement to prevent pulmonary embolus in patients with vena caval tumor thrombi / D.W.Brenner [et. al.] // J. Urol. 1992. Vol.147, №1. P.19-23.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Transvenous interruption of the inferior vena cava. New model of vena cava filter. Preliminary results in 35 cases / L.Castellani [et al.] // Int. Angiol. 1987. Vol.6, №3.Р.299-306</mixed-citation><mixed-citation xml:lang="en">Transvenous interruption of the inferior vena cava. New model of vena cava filter. Preliminary results in 35 cases / L.Castellani [et al.] // Int. Angiol. 1987. Vol.6, №3.Р.299-306</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Epidemiology, pathophysiology and natural history of venous thromboembolism / G.Cina [et. al.] // Raus. 1996. Vol.21, №3. P.315-327.</mixed-citation><mixed-citation xml:lang="en">Epidemiology, pathophysiology and natural history of venous thromboembolism / G.Cina [et. al.] // Raus. 1996. Vol.21, №3. P.315-327.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Experience with the Amplatz retrievable vena caval filter. Work in progress / M.D.Darcy [et. al.] // Radiology. 1986. Vol.161, №3. P.611-614.</mixed-citation><mixed-citation xml:lang="en">Experience with the Amplatz retrievable vena caval filter. Work in progress / M.D.Darcy [et. al.] // Radiology. 1986. Vol.161, №3. P.611-614.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Diebold J., Löhrs U. Venous thrombosis and pulmonary embolism: a study of 5039 autopsies // Pathol. Res. Pract. 1991. Vol.187, №2-3. P.220-226.</mixed-citation><mixed-citation xml:lang="en">Diebold J., Löhrs U. Venous thrombosis and pulmonary embolism: a study of 5039 autopsies // Pathol. Res. Pract. 1991. Vol.187, №2-3. P.220-226.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Clinical epidemiology of venous thromboembolic disease. Results of a French Multicentre registry / E.Ferrari [et al.] // Eur. Heart J. 1997. Vol.18, №4. P.685-691.</mixed-citation><mixed-citation xml:lang="en">Clinical epidemiology of venous thromboembolic disease. Results of a French Multicentre registry / E.Ferrari [et al.] // Eur. Heart J. 1997. Vol.18, №4. P.685-691.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Vena caval filter to prevent pulmonary embolism: experimental study. Work in progress / R.W.Günther [et. al.] // Radiology. 1985. Vol. 156, №2. P.315-320.</mixed-citation><mixed-citation xml:lang="en">Vena caval filter to prevent pulmonary embolism: experimental study. Work in progress / R.W.Günther [et. al.] // Radiology. 1985. Vol. 156, №2. P.315-320.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Gardner M. Surgery in the prevention of fatal pulmonary embolism with some observations on the morbid anatomy of veins // Ann. Roy. Coll. Surg. Eng. 1970. Vol.47, №5. P.260-270.</mixed-citation><mixed-citation xml:lang="en">Gardner M. Surgery in the prevention of fatal pulmonary embolism with some observations on the morbid anatomy of veins // Ann. Roy. Coll. Surg. Eng. 1970. Vol.47, №5. P.260-270.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Jing Z., Lu P., Cao G. Comparative study of ultrasonic detection of popliteal vein reflux // Zhonghua Wai Ke Za Zhi. 1995. Vol.33, №2. P.108-111.</mixed-citation><mixed-citation xml:lang="en">Jing Z., Lu P., Cao G. Comparative study of ultrasonic detection of popliteal vein reflux // Zhonghua Wai Ke Za Zhi. 1995. Vol.33, №2. P.108-111.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Johansson E., Nordlander S., Zetterquist S. Venous thrombectomy in the lower extremity-clinical, phlebographic and plethysmographic evaluation of early and late results // Acta. Chir. Scand. 1973. Vol.139, №6. Р.511-516.</mixed-citation><mixed-citation xml:lang="en">Johansson E., Nordlander S., Zetterquist S. Venous thrombectomy in the lower extremity-clinical, phlebographic and plethysmographic evaluation of early and late results // Acta. Chir. Scand. 1973. Vol.139, №6. Р.511-516.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Predictors of survival after deep vein thrombosis and pulmonary embolism: a population-based, cohort study / J.A.Heit [et. al.] // Arch. Intern. Med. 1999. Vol.159, №5. Р.445-453.</mixed-citation><mixed-citation xml:lang="en">Predictors of survival after deep vein thrombosis and pulmonary embolism: a population-based, cohort study / J.A.Heit [et. al.] // Arch. Intern. Med. 1999. Vol.159, №5. Р.445-453.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Keisker H.M., Bowers R.F. Results obtained by superficial femoral vein ligation // Surgery. 1960. Vol.47. P.224-229.</mixed-citation><mixed-citation xml:lang="en">Keisker H.M., Bowers R.F. Results obtained by superficial femoral vein ligation // Surgery. 1960. Vol.47. P.224-229.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Follow-up of vena cava filters with color Doppler ultrasound / W.Lang [et. al.] // Ultraschall Med. 1994. Vol.15, №6. P.312-316.</mixed-citation><mixed-citation xml:lang="en">Follow-up of vena cava filters with color Doppler ultrasound / W.Lang [et. al.] // Ultraschall Med. 1994. Vol.15, №6. P.312-316.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Cava filter for prevention of lung embolism: is implantation still justifield? / W.Lang [et al.] // Zentrabl. Chir. 1994. Vol.119. №9. Р.625-630.</mixed-citation><mixed-citation xml:lang="en">Cava filter for prevention of lung embolism: is implantation still justifield? / W.Lang [et al.] // Zentrabl. Chir. 1994. Vol.119. №9. Р.625-630.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Lindblad B., Sternby N.H., Bergqvist D. Incidence of venous thromboembolism verified by necropsy over 30 years // Br. Med. J. 1991. Vol.302, №6778. P.709-711.</mixed-citation><mixed-citation xml:lang="en">Lindblad B., Sternby N.H., Bergqvist D. Incidence of venous thromboembolism verified by necropsy over 30 years // Br. Med. J. 1991. Vol.302, №6778. P.709-711.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Klinische, funktionelle und morphologische Spatergebnisse nach venoser Thrombectomie / E.Minar [et. al.] // Vasa. 1983. Vol.12, №4. P.346-352.</mixed-citation><mixed-citation xml:lang="en">Klinische, funktionelle und morphologische Spatergebnisse nach venoser Thrombectomie / E.Minar [et. al.] // Vasa. 1983. Vol.12, №4. P.346-352.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Sandler D.A., Martin J.F. Autopsy proven pulmonary embolism in hospital patients: are we detecting enough deep vein thrombosis? // J. R. Soc. Med. 1989. Vol.82, №4. Р.203-205.</mixed-citation><mixed-citation xml:lang="en">Sandler D.A., Martin J.F. Autopsy proven pulmonary embolism in hospital patients: are we detecting enough deep vein thrombosis? // J. R. Soc. Med. 1989. Vol.82, №4. Р.203-205.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">D-dimer for the exclusion of acute venous thrombosis and pulmonary embolism: a systematic review / P.D.Stein [et. al.] // Ann. Intern. Med. 2004. Vol.140, №8. Р.589-602.</mixed-citation><mixed-citation xml:lang="en">D-dimer for the exclusion of acute venous thrombosis and pulmonary embolism: a systematic review / P.D.Stein [et. al.] // Ann. Intern. Med. 2004. Vol.140, №8. Р.589-602.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Tartulier M., Boutarin J., Ritz B. Chronic pulmonary thromboembolism // G. Ital. Cardiol. 1984. Vol.14, Suppl.1. P.13-21.</mixed-citation><mixed-citation xml:lang="en">Tartulier M., Boutarin J., Ritz B. Chronic pulmonary thromboembolism // G. Ital. Cardiol. 1984. Vol.14, Suppl.1. P.13-21.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Guidelines on diagnosis and management of acute pulmonary embolism. Task Force on Pulmonary Embolism, European Society of Cardiology / A.Torbicki [et. al.] // Eur. Heart J. 2000. Vol.21, №16. Р.1301-1336.</mixed-citation><mixed-citation xml:lang="en">Guidelines on diagnosis and management of acute pulmonary embolism. Task Force on Pulmonary Embolism, European Society of Cardiology / A.Torbicki [et. al.] // Eur. Heart J. 2000. Vol.21, №16. Р.1301-1336.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Guidelines on the diagnosis and management of acute pulmonary embolism. The Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC) / A.Torbicki [et. al.]. Eur. Heart J. 2008. Vol.29, №18. Р.2276-2315.</mixed-citation><mixed-citation xml:lang="en">Guidelines on the diagnosis and management of acute pulmonary embolism. The Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC) / A.Torbicki [et. al.]. Eur. Heart J. 2008. Vol.29, №18. Р.2276-2315.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
