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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cfpd</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень физиологии и патологии дыхания</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin Physiology and Pathology of Respiration</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1998-5029</issn><publisher><publisher-name>Дальневосточный научный центр физиологии и патологии дыхания</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">cfpd-715</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>ВЛИЯНИЕ ТАБАКОКУРЕНИЯ НА СВЯЗАННОЕ СО ЗДОРОВЬЕМ КАЧЕСТВО ЖИЗНИ У БОЛЬНЫХ БРОНХИАЛЬНОЙ АСТМОЙ</article-title><trans-title-group xml:lang="en"><trans-title>EFFECTS OF TOBACCO SMOKING ON HEALTH-RELATED QUALITY OF LIFE IN PATIENTS WITH ASTHMA</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Перельман</surname><given-names>Наталья Львовна</given-names></name><name name-style="western" xml:lang="en"><surname>Perelman</surname><given-names>Natal'ya L.</given-names></name></name-alternatives><email xlink:type="simple">lvovna63@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Дальневосточный научный центр физиологии и патологии Сибирского отделения РАМН</institution></aff><aff xml:lang="en"><institution>Far Eastern Scientific Center of Physiology and Pathology of Respiration SB RAMS</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>20</day><month>02</month><year>2020</year></pub-date><volume>0</volume><issue>53</issue><fpage>30</fpage><lpage>35</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Перельман Н.Л., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Перельман Н.Л.</copyright-holder><copyright-holder xml:lang="en">Perelman N.L.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cfpd.elpub.ru/jour/article/view/715">https://cfpd.elpub.ru/jour/article/view/715</self-uri><abstract><p>С целью оценки влияния табакокурения на связанное со здоровьем качество жизни больных бронхиальной астмой обследованы 96 пациентов, разделенных на три группы: активных курильщиков, бросивших курить и некурящих. Качество жизни оценивали с помощью вопросников SF-36 и AQLQ, состояние эмоциональной сферы посредством Госпитальной шкалы тревоги и депрессии. Уровень контроля астмы определяли по вопроснику АСТ. Функцию внешнего дыхания оценивали посредством спирометрии форсированного выдоха. В результате исследования установлено, что курящие больные бронхиальной астмой характеризуются существенно более низким уровнем общего и специфического качества жизни, ассоциированным с нарушением проходимости дистальных бронхов. Для них характерна бóльшая выраженность тревоги и депрессии, являющихся, по данным корреляционного анализа, одними из ведущих факторов снижения качества жизни больных. Разработаны регрессионные модели, отражающие взаимосвязь отдельных доменов общего и специфического качества жизни с уровнями тревоги и депрессии. Прекращение курения способствует существенному улучшению качества жизни и контроля бронхиальной астмы.</p></abstract><trans-abstract xml:lang="en"><p>In order to assess the impact of cigarette smoking on health-related quality of life in patients with asthma, 96 patients divided into three groups were examined: active smokers, ex-smokers and non-smokers. Quality of life was assessed using the SF-36 and AQLQ questionnaires, the state of the emotional sphere by means of the Hospital Anxiety and Depression Scale. The level of asthma control was determined by questionnaire ACT. Respiratory function was assessed by spirometry. The study found that smokers are characterized by significantly lower levels of general and specific quality of life associated with impaired patency of the distal airways. They are characterized by great severity of anxiety and depression, which are, according to the correlation analysis, one of the leading factors in reducing the quality of life of patients. Regression models were developed to reflect the relationship of the individual domains of general and specific quality of life with the levels of anxiety and depression. Quitting Smoking cessation contributes to a significant improvement in the quality of life and asthma control.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>бронхиальная астма</kwd><kwd>качество жизни</kwd><kwd>табакокурение</kwd><kwd>bronchial asthma</kwd><kwd>quality of life</kwd><kwd>tobacco smoking</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Перельман Н.Л. Влияние тревоги и депрессии на качество жизни больных бронхиальной астмой с холодовой гиперреактивностью дыхательных путей // Дальневост. мед. журн. 2009. №4. С.6−10.</mixed-citation><mixed-citation xml:lang="en">Перельман Н.Л. 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