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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">cfpd</journal-id><journal-title-group><journal-title xml:lang="ru">Бюллетень физиологии и патологии дыхания</journal-title><trans-title-group xml:lang="en"><trans-title>Bulletin Physiology and Pathology of Respiration</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1998-5029</issn><publisher><publisher-name>Дальневосточный научный центр физиологии и патологии дыхания</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.36604/1998-5029-2020-78-66-75</article-id><article-id custom-type="elpub" pub-id-type="custom">cfpd-836</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Технология определения клинико-анамнестических маркеров холодовой и осмотической гиперреактивности дыхательных путей</article-title><trans-title-group xml:lang="en"><trans-title>Technology for determining clinical-anamnestic markers of cold and osmotic airway hyperresponsiveness</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Афанасьева</surname><given-names>Е. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Afanas’eva</surname><given-names>Е. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Евгения Юрьевна Афанасьева, младший научный сотрудник, лаборатория функциональных методов исследования дыхательной системы</p><p>675000, г. Благовещенск, ул. Калинина, 22</p></bio><bio xml:lang="en"><p>Evgeniya Yu. Afanas’eva, MD, Junior Staff Scientist, Laboratory of Functional Research of Respiratory System </p><p>22 Kalinina Str., Blagoveshchensk, 675000</p></bio><email xlink:type="simple">evgeniyananev@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Приходько</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Prikhodko</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анна Григорьевна Приходько, д-р мед. наук, главный научный сотрудник, лаборатория функциональных методов исследования дыхательной системы</p><p>675000, г. Благовещенск, ул. Калинина, 22</p></bio><bio xml:lang="en"><p>Аnnа G. Prikhodko, MD, PhD, D.Sc. (Med.), Main Staff Scientist, Laboratory of Functional Research of Respiratory System </p><p>22 Kalinina Str., Blagoveshchensk, 675000</p></bio><email xlink:type="simple">prih-anya@ya.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Колосов</surname><given-names>В. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Kolosov</surname><given-names>V. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Виктор Павлович Колосов, академик РАН, д-р мед. наук, профессор, научный руководитель</p><p>675000, г. Благовещенск, ул. Калинина, 22</p></bio><bio xml:lang="en"><p>Victor P. Kolosov, Academician of RAS, MD, PhD, D.Sc. (Med.), Professor, Scientific Director </p><p>22 Kalinina Str., Blagoveshchensk, 675000</p></bio><email xlink:type="simple">kolosov@amur.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гребенюк</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Grebenyuk</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Александр Николаевич Гребенюк, д-р мед. наук, профессор</p><p>197022, г. Санкт-Петербург, ул. Льва Толстого, 6-8</p></bio><bio xml:lang="en"><p>Aleksandr N. Grebenyuk, MD, PhD, D.Sc. (Med.), Рrofessor </p><p>6/8 L'va Tolstogo Str., Saint Petersburg, 197022</p></bio><email xlink:type="simple">grebenyukan@nipigas.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Перельман</surname><given-names>Ю. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Perelman</surname><given-names>J. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юлий Михайлович Перельман, член-корреспондент РАН, д-р мед. наук, профессор, зам. директора по научной работе, зав. лабораторией функциональных методов исследования дыхательной системы</p><p>675000, г. Благовещенск, ул. Калинина, 22</p></bio><bio xml:lang="en"><p>Juliy M. Perelman, MD, PhD, D.Sc. (Med.), Corresponding member of RAS, Рrofessor, Deputy Director on Scientific Work, Head of Laboratory of Functional Research of Respiratory System </p><p>22 Kalinina Str., Blagoveshchensk, 675000</p></bio><email xlink:type="simple">jperelman@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное научное учреждение «Дальневосточный научный центр физиологии и патологии дыхания»</institution></aff><aff xml:lang="en"><institution>Far Eastern Scientific Center of Physiology and Pathology of Respiration</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования «Первый Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова»</institution></aff><aff xml:lang="en"><institution>Pavlov First Saint Petersburg State Medical University</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>17</day><month>12</month><year>2020</year></pub-date><volume>0</volume><issue>78</issue><fpage>66</fpage><lpage>75</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Афанасьева Е.Ю., Приходько А.Г., Колосов В.П., Гребенюк А.Н., Перельман Ю.М., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Афанасьева Е.Ю., Приходько А.Г., Колосов В.П., Гребенюк А.Н., Перельман Ю.М.</copyright-holder><copyright-holder xml:lang="en">Afanas’eva Е.Y., Prikhodko A.G., Kolosov V.P., Grebenyuk A.N., Perelman J.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://cfpd.elpub.ru/jour/article/view/836">https://cfpd.elpub.ru/jour/article/view/836</self-uri><abstract/><trans-abstract xml:lang="en"/><kwd-group xml:lang="ru"><kwd>бронхиальная астма</kwd><kwd>дистиллированная вода</kwd><kwd>осмотическая гиперреактивность дыхательных путей</kwd><kwd>холодовая гиперреактивность дыхательных путей</kwd><kwd>относительная влажность воздуха</kwd></kwd-group><kwd-group xml:lang="en"><kwd>asthma</kwd><kwd>distilled water</kwd><kwd>osmotic airway hyperresponsiveness</kwd><kwd>cold airway hyperresponsiveness</kwd><kwd>relative humidity</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Перельман Ю.М., Наумов Д.Е., Приходько А.Г., Колосов В.П. 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