cfpdБюллетень физиологии и патологии дыханияBulletin Physiology and Pathology of Respiration1998-5029Дальневосточный научный центр физиологии и патологии дыхания10.36604/1998-5029-2020-78-135-146cfpd-846Research ArticleОБЗОРЫREVIEWSОсобенности пневмоний, вызванных новым коронавирусом SARS-CoV-2 (обзор литературы)Peculiarities of community acquired pneumonia triggered by novel coronavirus SARS-CoV-2 (review)БазыкинаЕ. А.BazykinaE. A.

Елена Анатольевна Базыкина, младший научный сотрудник, лаборатория эпидемиологии и профилактики вирусных гепатитов и СПИД

680610, г. Хабаровск, ул. Шевченко, 2

Elena A. Bazykina, Junior Staff Scientist, Laboratory of Epidemiology and Prevention of Viral Hepatitis and AIDS 

2 Shevchenko Str., Khabarovsk, 680610

alyonaf@yandex.ruТроценкоО. Е.TrotsenkoO. E.

Ольга Евгеньевна Троценко, д-р мед. наук, директор 

680610, г. Хабаровск, ул. Шевченко, 2

Olga E. Trotsenko, MD, PhD, D.Sc. (Med.), Director 

2 Shevchenko Str., Khabarovsk, 680610

trotsenko_oe@hniiem.ruФедеральное бюджетное учреждение науки «Хабаровский научно-исследовательский институт эпидемиологии и микробиологии» Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человекаKhabarovsk Research Institute of Epidemiology and Microbiology of Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing202021122020078135146Copyright © Базыкина Е.А., Троценко О.Е., 20202020Базыкина Е.А., Троценко О.Е.Bazykina E.A., Trotsenko O.E.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://cfpd.elpub.ru/jour/article/view/846SARS-CoV-2пневмонияполимеразная цепная реакциякомпьютерная томографияко-инфекцияSARS-CoV-2pneumoniapolymerase chain reactioncomputer tomographyco-infectionReferencesБрико Н.И. 100 лет пандемии: уроки истории. Новый этап вакцинопрофилактики // Эпидемиология и вакцинопрофилактика. 2018. Т.4, №17. С.68‒75.Briko N.I. 100 Years after the Spanish Flu Pandemic. The Evolution of the Influenza Virus and the Development of the Flu Vaccine. Epidemiology and Vaccinal Prevention 2018; 17(4):68‒75 (in Russian).Jiang F., Deng L., Zhang L., Cai Y., Cheung C.W., Xia Z. Review of the Clinical Characteristics of Coronavirus Disease 2019 (COVID-19) // J. Gen. Intern. Med. 2020. Vol.35, №5. P.1545–1549. https://doi.org/10.1007/s11606-020-05762-wJiang F., Deng L., Zhang L., Cai Y., Cheung C.W., Xia Z. Review of the Clinical Characteristics of Coronavirus Disease 2019 (COVID-19). J. Gen. Intern. Med. 2020; 35(5):1545–1549. https://doi.org/10.1007/s11606-020-05762-wZhu N., Zhang D., Wang W., Li X., Yang B., Song J., Zhao X., Huang B., Shi W., Lu R., Niu P., Zhan F., Ma X., Wang D., Xu W., Wu G., Gao G.F., Tan W.; China Novel Coronavirus Investigating and Research Team. A Novel Coronavirus from Patients with Pneumonia in China, 2019 // N. Engl. J. Med. 2020. Vol.382, №8. P.727‒733. doi: 10.1056/NEJMoa2001017Zhu N., Zhang D., Wang W., Li X., Yang B., Song J., Zhao X., Huang B., Shi W., Lu R., Niu P., Zhan F., Ma X., Wang D., Xu W., Wu G., Gao G.F., Tan W.; China Novel Coronavirus Investigating and Research Team. A Novel Coronavirus from Patients with Pneumonia in China, 2019. N. Engl. J. Med. 2020; 382(8):727‒733. doi: 10.1056/NEJMoa2001017de Wit E., van Doremalen N., Falzarano D., Munster V.J. SARS and MERS: recent insights into emerging coronaviruses // Nat. Rev. Microbiol. 2016. Vol.14, №8. Р.523‒534. doi: 10.1038/nrmicro.2016.81de Wit E., van Doremalen N., Falzarano D., Munster V.J. SARS and MERS: recent insights into emerging coronaviruses. Nat. Rev. Microbiol. 2016; 14(8):523‒534. doi:10.1038/nrmicro.2016.81Wang Y., Wang Y., Chen Y., Qin Q. Unique epidemiological and clinical features of the emerging 2019 novel coronavirus pneumonia (COVID-19) implicate special control measures // J. Med. Virol. 2020. Vol.92, №6. P.568‒576. doi: 10.1002/jmv.25748Wang Y., Wang Y., Chen Y., Qin Q. Unique epidemiological and clinical features of the emerging 2019 novel coronavirus pneumonia (COVID-19) implicate special control measures. J. Med. Virol. 2020; 92(6):568‒576. doi: 10.1002/jmv.25748Park J.E., Soyoung J., Aeran K., Park J.E. MERS transmission and risk factors: a systematic review // BMC Public Health. 2018. Vol.18, №1. Article number 574. doi: 10.1186/s12889-018-5484-8Park J.E., Soyoung J., Aeran K., Park J.E. MERS transmission and risk factors: a systematic review. BMC Public Health 2018; 18:574. doi: 10.1186/s12889-018-5484-8Huang C., Wang Y., Li X., Ren L., Zhao J., Hu Y., Zhang L., Fan G., Xu J., Gu X., Cheng Z., Yu T., Xia J., Wei Y., Wu W., Xie X., Yin W., Li H., Liu M., Xiao Y., Gao H., Guo L., Xie J., Wang G., Jiang R., Gao Z., Jin Q., Wang J., Cao B. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China // Lancet. 2020. Vol.95, №10223. Р.497‒506. doi: 10.1016/S0140-6736(20)30183-5Huang C., Wang Y., Li X., Ren L., Zhao J., Hu Y., Zhang L., Fan G., Xu J., Gu X., Cheng Z., Yu T., Xia J., Wei Y., Wu W., Xie X., Yin W., Li H., Liu M., Xiao Y., Gao H., Guo L., Xie J., Wang G., Jiang R., Gao Z., Jin Q., Wang J., Cao B. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020; 395(10223):497‒506. doi: 10.1016/S0140-6736(20)30183-5Wang D, Hu B, Hu C., Zhu F., Liu X., Zhang J., Wang B, Xiang H., Cheng Z., Xiong Y., Zhao Y., Li Y., Wang X., Peng Z. Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China // JAMA. 2020. Vol.323, №11. Р.1061‒1069. doi: 10.1001/jama.2020.1585Wang D, Hu B, Hu C., Zhu F., Liu X., Zhang J., Wang B, Xiang H., Cheng Z., Xiong Y., Zhao Y., Li Y., Wang X., Peng Z. Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. JAMA 2020; 323(11):1061‒1069. doi: 10.1001/jama.2020.1585Varatharaj A., Thomas N., Ellul M.A., Davies N.W.S., Pollak T.A., Tenorio E.L., Sultan M., Easton A., Breen G., Zandi M., Coles J.P., Manji H., Al-Shahi Salman R., Menon D.K., Nicholson T.R., Benjamin L.A., Carson A., Smith C., Turner M.R., Solomon T., Kneen R., Pett S.L., Galea I., Thomas R.H., Michael B.D.; CoroNerve Study Group. Neurological and neuropsychiatric complications of COVID-19 in 153 patients: a UK-wide surveillance study // Lancet Psychiatry. 2020. Vol.7, №10. Р.875‒882. doi: 10.1016/S2215-0366(20)30287-XVaratharaj A., Thomas N., Ellul M.A., Davies N.W.S., Pollak T.A., Tenorio E.L., Sultan M., Easton A., Breen G., Zandi M., Coles J.P., Manji H., Al-Shahi Salman R., Menon D.K., Nicholson T.R., Benjamin L.A., Carson A., Smith C., Turner M.R., Solomon T., Kneen R., Pett S.L., Galea I., Thomas R.H., Michael B.D.; CoroNerve Study Group. Neurological and neuropsychiatric complications of COVID-19 in 153 patients: a UK-wide surveillance study. Lancet Psychiatry 2020; 7(10):875‒882. doi: 10.1016/S2215-0366(20)30287-XJin Y.H., Cai L., Cheng Z.S., Cheng H., Deng T., Fan Y.P., Fang C., Huang D., Huang L.Q., Huang Q., Han Y., Hu B., Hu F., Li B.H,. Li Y.R., Liang K., Lin L.K., Luo L.S., Ma J., Ma L.L., Peng Z.Y., Pan Y.B., Pan Z.Y., Ren X.Q., Sun H.M., Wang Y., Wang Y.Y., Weng H., Wei C.J., Wu D.F., Xia J., Xiong Y., Xu H.B., Yao X.M., Yuan Y.F., Ye T.S., Zhang X.C., Zhang Y.W., Zhang Y.G., Zhang H.M., Zhao Y., Zhao M.J., Zi H., Zeng X.T., Wang Y.Y., Wang X.H. A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version) // Mil. Med. Res. 2020. Vol.7, №1. Article number 4. doi: 10.1186/s40779-020-0233-6Jin Y.H., Cai L., Cheng Z.S., Cheng H., Deng T., Fan Y.P., Fang C., Huang D., Huang L.Q., Huang Q., Han Y., Hu B., Hu F., Li B.H,. Li Y.R., Liang K., Lin L.K., Luo L.S., Ma J., Ma L.L., Peng Z.Y., Pan Y.B., Pan Z.Y., Ren X.Q., Sun H.M., Wang Y., Wang Y.Y., Weng H., Wei C.J., Wu D.F., Xia J., Xiong Y., Xu H.B., Yao X.M., Yuan Y.F., Ye T.S., Zhang X.C., Zhang Y.W., Zhang Y.G., Zhang H.M., Zhao Y., Zhao M.J., Zi H., Zeng X.T., Wang Y.Y., Wang X.H. A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version). Mil. Med. Res. 2020; 7(1):4. doi: 10.1186/s40779-020-0233-6Transmission of SARS-CoV-2: implications for infection prevention precautions. WHO Scientific Brief (9 July 2020). URL: https://www.who.int/news-room/commentaries/detail/transmission-of-sars-cov-2-implications-for-infectionprevention-precautions (дата обращения 18.07.2020).Transmission of SARS-CoV-2: implications for infection prevention precautions. WHO Scientific Brief (9 July 2020). Available at: https://www.who.int/news-room/commentaries/detail/transmission-of-sars-cov-2-implications-for-infection-prevention-precautionsWu Y., Guo C., Tang L., Hong Z., Zhou J., Dong X., Yin H., Xiao Q., Tang Y., Qu X., Kuang L., Fang X., Mishra N., Lu J., Shan H., Jiang G., Huang X. Prolonged presence of SARS-CoV-2 viral RNA in faecal samples // Lancet Gastroenterol. Hepatol. 2020. Vol.5, №5. Р.434‒435. doi: 10.1016/S2468-1253(20)30083-2Wu Y., Guo C., Tang L., Hong Z., Zhou J., Dong X., Yin H., Xiao Q., Tang Y., Qu X., Kuang L., Fang X., Mishra N., Lu J., Shan H., Jiang G., Huang X. Prolonged presence of SARS-CoV-2 viral RNA in faecal samples. Lancet Gastroenterol. Hepatol. 2020; 5(5):434‒435. doi: 10.1016/S2468-1253(20)30083-2Sun J., Zhu A., Li H., Zheng K., Zhuang Z., Chen Z., Shi Y., Zhang Z., Chen S.B., Liu X., Dai J., Li X., Huang S., Huang X., Luo L., Wen L., Zhuo J., Li Y., Wang Y., Zhang L., Zhang Y., Li F., Feng L., Chen X., Zhong N., Yang Z., Huang J., Zhao J., Li Y.M. Isolation of infectious SARS-CoV-2 from urine of a COVID-19 patient // Emerg. Microbes Infect. 2020. Vol.9, №1. Р.991‒993. doi: 10.1080/22221751.2020.1760144Sun J., Zhu A., Li H., Zheng K., Zhuang Z., Chen Z., Shi Y., Zhang Z., Chen S.B., Liu X., Dai J., Li X., Huang S., Huang X., Luo L., Wen L., Zhuo J., Li Y., Wang Y., Zhang L., Zhang Y., Li F., Feng L., Chen X., Zhong N., Yang Z., Huang J., Zhao J., Li Y.M. Isolation of infectious SARS-CoV-2 from urine of a COVID-19 patient. Emerg. Microbes Infect. 2020; 9(1):991‒993. doi: 10.1080/22221751.2020.1760144Wang W., Xu Y., Gao R., Lu R., Han K., Wu G., Tan W. Detection of SARS-CoV-2 in Different Types of Clinical Specimens // JAMA. 2020. Vol.323, №18. Р.1843‒1844. doi: 10.1001/jama.2020.3786Wang W., Xu Y., Gao R., Lu R., Han K., Wu G., Tan W. Detection of SARS-CoV-2 in Different Types of Clinical Specimens. JAMA 2020; 323(18):1843‒1844. doi: 10.1001/jama.2020.3786García L.F. Immune Response, Inflammation, and the Clinical Spectrum of COVID-19 // Front. Immunol. 2020. Vol.11. Article number 1441. doi: 10.3389/fimmu.2020.01441García L.F. Immune Response, Inflammation, and the Clinical Spectrum of COVID-19. Front. Immunol. 2020; 11:1441. doi: 10.3389/fimmu.2020.01441Wu J.H., Li X., Huang B., Su H., Li Y., Luo D.J., Chen S., Ma L., Wang S.H., Nie X., Peng L. Pathological changes of fatal coronavirus disease 2019 (COVID-19) in the lungs: report of 10 cases by postmortem needle autopsy // Zhonghua Bing Li Xue Za Zhi. 2020. Vol.49, №6. P.568‒575. doi: 10.3760/cma.j.cn112151-20200405-00291Wu J.H., Li X., Huang B., Su H., Li Y., Luo D.J., Chen S., Ma L., Wang S.H., Nie X., Peng L. Pathological changes of fatal coronavirus disease 2019 (COVID-19) in the lungs: report of 10 cases by postmortem needle autopsy. Zhonghua Bing Li Xue Za Zhi 2020; 49(6):568‒575 (in Chinese). doi: 10.3760/cma.j.cn112151-20200405-00291Zhou P., Yang X.L., Wang X.G., Hu B., Zhang L., Zhang W., Si H.R., Zhu Y., Li B., Huang C.L,. Chen H.D., Chen J,. Luo Y., Guo H., Jiang R.D., Liu M.Q., Chen Y., Shen X.R., Wang X., Zheng X.S., Zhao K., Chen Q.J., Deng F., Liu L.L., Yan B., Zhan F.X., Wang Y.Y., Xiao G.F., Shi Z.L. A pneumonia outbreak associated with a new coronavirus of probable bat origin // Nature. 2020. Vol.579, №7798. Р. 270‒273. doi: 10.1038/s41586-020-2012-7Zhou P., Yang X.L., Wang X.G., Hu B., Zhang L., Zhang W., Si H.R., Zhu Y., Li B., Huang C.L,. Chen H.D., Chen J,. Luo Y., Guo H., Jiang R.D., Liu M.Q., Chen Y., Shen X.R., Wang X., Zheng X.S., Zhao K., Chen Q.J., Deng F., Liu L.L., Yan B., Zhan F.X., Wang Y.Y., Xiao G.F., Shi Z.L. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature 2020; 579(7798):270‒273. doi: 10.1038/s41586-020-2012-7Harmer D., Gilbert M., Borman R., Clark K. L. Quantitative mRNA expression profiling of ACE 2, a novel homologue of angiotensin converting enzyme // FEBS Lett. 2002. Vol.532. №1-2. P.107‒110. doi: 10.1016/s0014-5793(02)03640-2Harmer D., Gilbert M., Borman R., Clark K. L. Quantitative mRNA expression profiling of ACE 2, a novel homologue of angiotensin converting enzyme. FEBS Lett. 2002; 532(1-2):107‒110. doi: 10.1016/s0014-5793(02)03640-2Lin L., Lu L., Cao W., Li T. Hypothesis for potential pathogenesis of SARS-CoV-2 infection-a review of immune changes in patients with viral pneumonia // Emerg. Microbes Infect. 2020. Vol.9, №1. P.727‒732. doi: 10.1080/22221751.2020.1746199Lin L., Lu L., Cao W., Li T. Hypothesis for potential pathogenesis of SARS-CoV-2 infection-a review of immune changes in patients with viral pneumonia. Emerg. Microbes Infect. 2020; 9(1):727‒732. doi: 10.1080/22221751.2020.1746199Hu Y., Deng H., Huang L., Xia L., Zhou X. Analysis of Characteristics in Death Patients with COVID-19 Pneumonia without Underlying Diseases // Acad. Radiol. 2020. Vol.27, №5. Article number 752. doi: 10.1016/j.acra.2020.03.023Hu Y., Deng H., Huang L., Xia L., Zhou X. Analysis of Characteristics in Death Patients with COVID-19 Pneumonia without Underlying Diseases. Acad. Radiol. 2020; 27(5):752. doi: 10.1016/j.acra.2020.03.023Li L., Zhang B., He B., Gong Z., Chen X. Critical patients with coronavirus disease 2019: Risk factors and outcome nomogram // J. Infect. 2020. Vol.80, №6. e37‒e38. doi: 10.1016/j.jinf.2020.03.025Li L., Zhang B., He B., Gong Z., Chen X. Critical patients with coronavirus disease 2019: Risk factors and outcome nomogram. J. Infect. 2020; 80(6):e37‒e38. doi: 10.1016/j.jinf.2020.03.025Wang F., Nie J., Wang H., Zhao Q., Xiong Y., Deng L., Song S., Ma Z., Mo P., Zhang Y. Characteristics of Peripheral Lymphocyte Subset Alteration in COVID-19 Pneumonia // J. Infect. Dis. 2020. Vol.221. №11. P.1762‒1769. doi: 10.1093/infdis/jiaa150Wang F., Nie J., Wang H., Zhao Q., Xiong Y., Deng L., Song S., Ma Z., Mo P., Zhang Y. Characteristics of Peripheral Lymphocyte Subset Alteration in COVID-19 Pneumonia. J. Infect. Dis. 2020; 221(11):1762‒1769. doi: 10.1093/infdis/jiaa150Liu Y., Yang Y., Zhang C., Huang F., Wang F., Yuan J., Wang Z., Li J., Li J., Feng C., Zhang Z., Wang L., Peng L., Chen L., Qin Y., Zhao D., Tan S., Yin L., Xu J., Zhou C., Jiang C., Liu L. Clinical and biochemical indexes from 2019- nCoV infected patients linked to viral loads and lung injury // Sci. China Life Sci. 2020. Vol.63, №3. P.364‒374. doi: 10.1007/s11427-020-1643-8Liu Y., Yang Y., Zhang C., Huang F., Wang F., Yuan J., Wang Z., Li J., Li J., Feng C., Zhang Z., Wang L., Peng L., Chen L., Qin Y., Zhao D., Tan S., Yin L., Xu J., Zhou C., Jiang C., Liu L. Clinical and biochemical indexes from 2019-nCoV infected patients linked to viral loads and lung injury. Sci. China Life Sci. 2020; 63(3):364‒374. doi: 10.1007/s11427-020-1643-8Liu X., Zhou H., Zhou Y., Wu X., Zhao Y., Lu Y., Tan W., Yuan M., Ding X., Zou J., Li R., Liu H., Ewing R.M., Hu Y., Nie H., Wang Y. Risk factors associated with disease severity and length of hospital stay in COVID-19 patients // J. Infect. 2020. Vol.81, №1. e95‒e97. doi: 10.1016/j.jinf.2020.04.008Liu X., Zhou H., Zhou Y., Wu X., Zhao Y., Lu Y., Tan W., Yuan M., Ding X., Zou J., Li R., Liu H., Ewing R.M., Hu Y., Nie H., Wang Y. Risk factors associated with disease severity and length of hospital stay in COVID-19 patients. J. Infect. 2020; 81(1).e95‒e97. doi: 10.1016/j.jinf.2020.04.008Li L., Zhang B., He B., Gong Z., Chen X. Critical patients with coronavirus disease 2019: Risk factors and outcome nomogram // J. Infect. 2020. Vol. 80, №6. e37‒e38. doi: 10.1016/j.jinf.2020.03.025Li L., Zhang B., He B., Gong Z., Chen X. Critical patients with coronavirus disease 2019: Risk factors and outcome nomogram. J. Infect. 2020; 80(6):e37‒e38. doi: 10.1016/j.jinf.2020.03.025Porfidia A., Pola R. Venous thromboembolism in COVID-19 patients // J. Thromb. Haemost. 2020. Vol.18, №6. P.1516‒1517. doi: 10.1111/jth.14842Porfidia A., Pola R. Venous thromboembolism in COVID-19 patients. J. Thromb. Haemost. 2020; 18(6):1516‒1517. doi: 10.1111/jth.14842Guevara-Noriega K.A., Lucar-Lopez G.A., Nuñez G., Rivera-Aguasvivas L., Chauhan I. Coagulation Panel in Patients with SARS-CoV2 Infection (COVID-19) // Ann. Clin. Lab. Sci. 2020. Vol.50, №3. P.295‒298.Guevara-Noriega K.A., Lucar-Lopez G.A., Nuñez G., Rivera-Aguasvivas L., Chauhan I. Coagulation Panel in Patients with SARS-CoV2 Infection (COVID-19). Ann. Clin. Lab. Sci. 2020; 50(3):295‒298.Du R.H., Liang L.R., Yang C.Q., Wang W., Cao T.Z., Li M., Guo G.Y., Du J., Zheng C.L., Zhu Q,. Hu M., Li X.Y., Peng P., Shi H.Z. Predictors of mortality for patients with COVID-19 pneumonia caused by SARS-CoV-2: a prospective cohort study // Eur. Respir. J. 2020. Vol.55, №5. Article number 2000524. doi: 10.1183/13993003.00524-2020Du R.H., Liang L.R., Yang C.Q., Wang W., Cao T.Z., Li M., Guo G.Y., Du J., Zheng C.L., Zhu Q,. Hu M., Li X.Y., Peng P., Shi H.Z. Predictors of mortality for patients with COVID-19 pneumonia caused by SARS-CoV-2: a prospective cohort study. Eur. Respir. J. 2020; 55(5):2000524. doi: 10.1183/13993003.00524-2020Ackermann M., Verleden S.E., Kuehnel M., Haverich A., Welte T., Laenger F., Vanstapel A., Werlein C., Stark H., Tzankov A., Li W.W., Li V.W., Mentzer S.J., Jonigk D. Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19 // N. Engl. J. Med. 2020. Vol.383, №2. Р.120‒128. doi: 10.1056/NEJMoa2015432Ackermann M., Verleden S.E., Kuehnel M., Haverich A., Welte T., Laenger F., Vanstapel A., Werlein C., Stark H., Tzankov A., Li W.W., Li V.W., Mentzer S.J., Jonigk D. Pulmonary Vascular Endothelialitis, Thrombosis, and Angiogenesis in Covid-19. N. Engl. J. Med. 2020; 383(2):120‒128. doi: 10.1056/NEJMoa2015432Yang X., Yu Y., Xu J., Shu H., Xia J., Liu H., Wu Y., Zhang L., Yu Z., Fang M., Yu T., Wang Y., Pan S., Zou X., Yuan S., Shang Y. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study // Lancet Respir. Med. 2020. Vol.8, №5. P.475‒481. doi: 10.1016/S2213-2600(20)30079-5Yang X., Yu Y., Xu J., Shu H., Xia J., Liu H., Wu Y., Zhang L., Yu Z., Fang M., Yu T., Wang Y., Pan S., Zou X., Yuan S., Shang Y. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. Lancet Respir. Med. 2020; 8(5):475‒481. doi: 10.1016/S2213-2600(20)30079-5Lansbury L., Lim B., Baskaran V., Lim W.S. Co-infections in people with COVID-19: a systematic review and meta-analysis // J. Infect. 2020. Vol.81, №2. Р.266‒275. doi: 10.1016/j.jinf.2020.05.046Lansbury L., Lim B., Baskaran V., Lim W.S. Co-infections in people with COVID-19: a systematic review and meta-analysis. J. Infect. 2020; 81(2):266‒275. doi: 10.1016/j.jinf.2020.05.046Póvoa H.C.C., Chianca G.C., Iorio N.L.P.P. COVID-19: An Alert to Ventilator-Associated Bacterial // Infect. Dis. Ther. 2020. Vol.9, №3. Р.417‒420. doi: 10.1007/s40121-020-00306-5Póvoa HC.C., Chianca G.C., Iorio N.L.P.P. COVID-19: An Alert to Ventilator-Associated Bacterial. Infect. Dis. Ther. 2020; 9(3):417‒420. doi: 10.1007/s40121-020-00306-5Орлова О.А., Акимкин В.Г. Организация эпидемиологической диагностики вентилятор-ассоциированных инфекций дыхательных путей // Медицинский алфавит. 2017. Т.3, № 30. С.15‒19.Orlova O.A., Akimkin V.G. Organization of epidemiological diagnosis of ventilator-associated respiratory infections. Medical alphabet 2017; 3(30):15‒19 (in Russian).Teng F., Liu X., Guo S.B., Li Z., Ji W.Q., Zhang F., Zhu X.M. Community-acquired bacterial co-infection predicts severity and mortality in influenza-associated pneumonia admitted patients // J. Infect. Chemother. 2019. Vol.25, №2. P.129‒136. doi: 10.1016/j.jiac.2018.10.014Teng F., Liu X., Guo S.B., Li Z., Ji W.Q., Zhang F., Zhu X.M. Community-acquired bacterial co-infection predicts severity and mortality in influenza-associated pneumonia admitted patients. J. Infect. Chemother. 2019; 25(2):129‒136. doi: 10.1016/j.jiac.2018.10.014Nowak M.D., Sordillo E.M., Gitman M.R., Paniz Mondolfi A.E. Co-infection in SARS-CoV-2 infected Patients: Where Are Influenza Virus and Rhinovirus/Enterovirus? // J. Med. Virol. 2020. https://doi.org/10.1002/jmv.25953Nowak M.D., Sordillo E.M., Gitman M.R., Paniz Mondolfi A.E. Co-infection in SARS-CoV-2 infected Patients: Where Are Influenza Virus and Rhinovirus/Enterovirus? J. Med. Virol. 2020. https://doi.org/10.1002/jmv.25953Kreitmann L., Monard C., Dauwalder O., Simon M., Argaud L. Early bacterial co-infection in ARDS related to COVID-19 // Intensive Care Med. 2020. Vol.46, №9. Р.1787‒1789. doi: 10.1007/s00134-020-06165-5Kreitmann L., Monard C., Dauwalder O., Simon M., Argaud L. Early bacterial co-infection in ARDS related to COVID-19. Intensive Care Med. 2020; 46(9):1787‒1789. doi: 10.1007/s00134-020-06165-5Cucchiari D., Pericàs J.M., Riera J., Gumucio R., Coloma E., Nicolás D. Pneumococcal superinfection in COVID19 patients: A series of 5 cases // Med. Clin. (Barc). 2020. doi: 10.1016/j.medcli.2020.05.022Cucchiari D., Pericàs J.M., Riera J., Gumucio R., Coloma E., Nicolás D. Pneumococcal superinfection in COVID19 patients: A series of 5 cases. Med. Clin. (Barc). 2020. doi: 10.1016/j.medcli.2020.05.022He G., Wu J., Shi J., Dai J., Gamber M., Jiang X., Sun W., Cai J. COVID-19 in tuberculosis patients: A report of three cases // J. Med. Virol. 2020. 10.1002/jmv.25943. doi: 10.1002/jmv.25943He G., Wu J., Shi J., Dai J., Gamber M., Jiang X., Sun W., Cai J. COVID-19 in tuberculosis patients: A report of three cases. J. Med. Virol. 2020. 10.1002/jmv.25943. doi: 10.1002/jmv.25943Chaudhary W.A., Chong P.L., Mani B.I., Asli R., Momin R.N., Abdullah M.S., Chong V.H. Primary Respiratory Bacterial Coinfections in Patients with COVID-19 // Am. J. Trop. Med. Hyg. 2020. Vol.103, №2. Р.917‒919. doi: 10.4269/ajtmh.20-0498Chaudhary W.A., Chong P.L., Mani B.I., Asli R., Momin R.N., Abdullah M.S., Chong V.H. Primary Respiratory Bacterial Coinfections in Patients with COVID-19. Am. J. Trop. Med. Hyg. 2020; 103(2):917‒919. doi: 10.4269/ajtmh.20-0498Zhou Y., Guo S., He Y., Zuo Q., Liu D., Xiao M., Fan J., Li X. COVID-19 Is Distinct From SARS-CoV-2-Negative Community-Acquired Pneumonia // Front. Cell. Infect. Microbiol. 2020. Vol.10. Article number 322. doi: 10.3389/fcimb.2020.00322Zhou Y., Guo S., He Y., Zuo Q., Liu D., Xiao M., Fan J., Li X. COVID-19 Is Distinct From SARS-CoV-2-Negative Community-Acquired Pneumonia. Front. Cell. Infect. Microbiol. 2020; 10:322. doi: 10.3389/fcimb.2020.00322Xia T., Li J., Gao J., Xu X. Small Solitary Ground-Glass Nodule on CT as an Initial Manifestation of Coronavirus Disease 2019 (COVID-19) Pneumonia // Korean J. Radiol. 2020. Vol.21, №5. P.545‒549. doi:10.3348/kjr.2020.0240Xia T., Li J., Gao J., Xu X. Small Solitary Ground-Glass Nodule on CT as an Initial Manifestation of Coronavirus Disease 2019 (COVID-19) Pneumonia. Korean J. Radiol. 2020; 21(5):545‒549. doi: 10.3348/kjr.2020.0240Song F., Shi N., Shan F., Zhang Z., Shen J., Lu H., Ling Y., Jiang Y., Shi Y. Emerging 2019 Novel Coronavirus (2019-nCoV) Pneumonia // Radiology. 2020. Vol.295, №1. Р.210‒217. doi: 10.1148/radiol.2020200274Song F., Shi N., Shan F., Zhang Z., Shen J., Lu H., Ling Y., Jiang Y., Shi Y. Emerging 2019 Novel Coronavirus (2019-nCoV) Pneumonia. Radiology 2020; 295(1):210‒217. doi: 10.1148/radiol.2020200274Shi H., Han X., Jiang N., Cao Y., Alwalid O., Gu J., Fan Y., Zheng C. Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study // Lancet Infect. Dis. 2020. Vol.20, №4. P.425‒434. doi: 10.1016/S1473-3099(20)30086-4Shi H., Han X., Jiang N., Cao Y., Alwalid O., Gu J., Fan Y., Zheng C. Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study. Lancet Infect. Dis. 2020; 20(4):425‒434. doi: 10.1016/S1473-3099(20)30086-4Pan Y., Guan H., Zhou S., Wang Y., Li Q., Zhu T., Hu Q., Xia L. Initial CT findings and temporal changes in patients with the novel coronavirus pneumonia (2019-nCoV): a study of 63 patients in Wuhan, China // Eur. Radiol. 2020. Vol.30, №6. P.3306‒3309. doi: 10.1007/s00330-020-06731-xPan Y., Guan H., Zhou S., Wang Y., Li Q., Zhu T., Hu Q., Xia L. Initial CT findings and temporal changes in patients with the novel coronavirus pneumonia (2019-nCoV): a study of 63 patients in Wuhan, China. Eur. Radiol. 2020; 30(6):3306‒3309. doi: 10.1007/s00330-020-06731-xBhat R., Hamid A., Kunin J.R., Saboo S.S., Batra K., Baruah D., Bhat A.P. Chest Imaging in Patients Hospitalized With COVID-19 Infection ‒ A Case Series // Curr. Probl. Diagn. Radiol. 2020. Vol.49, №4. P.294‒301. doi: 10.1067/j.cpradiol.2020.04.001Bhat R., Hamid A., Kunin J.R., Saboo S.S., Batra K., Baruah D., Bhat A.P. Chest Imaging in Patients Hospitalized With COVID-19 Infection ‒ A Case Series. Curr. Probl. Diagn. Radiol. 2020; 49(4):294‒301. doi: 10.1067/j.cpradiol.2020.04.001Sun R., Liu H., Wang X. Mediastinal Emphysema, Giant Bulla, and Pneumothorax Developed during the Course of COVID-19 Pneumonia // Korean J. Radiol. 2020. Vol.21, №5. P.541‒544. doi: 10.3348/kjr.2020.0180Sun R., Liu H., Wang X. Mediastinal Emphysema, Giant Bulla, and Pneumothorax Developed during the Course of COVID-19 Pneumonia. Korean J. Radiol. 2020; 21(5):541‒544. doi: 10.3348/kjr.2020.0180Wang J., Su X., Zhang T., Zheng C. Spontaneous Pneumomediastinum: A Probable Unusual Complication of Coronavirus Disease 2019 (COVID-19) Pneumonia // Korean J. Radiol. 2020. Vol.21, №5. P.627‒628. doi: 10.3348/kjr.2020.0281Wang J., Su X., Zhang T., Zheng C. Spontaneous Pneumomediastinum: A Probable Unusual Complication of Coronavirus Disease 2019 (COVID-19) Pneumonia. Korean J. Radiol. 2020; 21(5):627‒628. doi: 10.3348/kjr.2020.0281Tian X.L., Peng M., Wang H.P., Cai B.Q., Xu W.B., Zhu Y.J., Li T.S., Zhu H.D., Song L., Wang M.Z., Zhang L., Shi J.H. The differential diagnosis for novel coronavirus pneumonia and similar lung diseases in general hospitals // Zhonghua Jie He He Hu Xi Za Zhi. 2020. Vol.43, №5. P.401‒408 (in Chinese). doi: 10.3760/cma.j.cn112147-20200221-00136Tian X.L., Peng M., Wang H.P., Cai B.Q., Xu W.B., Zhu Y.J., Li T.S., Zhu H.D., Song L., Wang M.Z., Zhang L., Shi J.H. The differential diagnosis for novel coronavirus pneumonia and similar lung diseases in general hospitals. Zhonghua Jie He He Hu Xi Za Zhi 2020; 43(5):401‒408 (in Chinese). doi: 10.3760/cma.j.cn112147-20200221-00136Lin C., Ding Y., Xie B., Sun Z., Li X., Chen Z., Niu M. Asymptomatic novel coronavirus pneumonia patient outside Wuhan: The value of CT images in the course of the disease // Clin. Imaging. 2020. Vol.63. P.7‒9. doi: 10.1016/j.clinimag.2020.02.008Lin C., Ding Y., Xie B., Sun Z., Li X., Chen Z., Niu M. Asymptomatic novel coronavirus pneumonia patient outside Wuhan: The value of CT images in the course of the disease. Clin. Imaging 2020; 63:7‒9. doi: 10.1016/j.clinimag.2020.02.008Hase R., Kurita T., Muranaka E., Sasazawa H., Mito H., Yano Y. A case of imported COVID-19 diagnosed by PCR-positive lower respiratory specimen but with PCR-negative throat swabs // Infect. Dis. (Lond). 2020. Vol.52, №6. P.423‒426. doi: 10.1080/23744235.2020.1744711Hase R., Kurita T., Muranaka E., Sasazawa H., Mito H., Yano Y. A case of imported COVID-19 diagnosed by PCR-positive lower respiratory specimen but with PCR-negative throat swabs. Infect. Dis. (Lond) 2020; 52(6):423‒426. doi: 10.1080/23744235.2020.1744711Hornuss D., Laubner K., Monasterio C., Thimme R., Wagner D. COVID-19 associated pneumonia despite repeatedly negative PCR-analysis from oropharyngeal swabs // Dtsch Med. Wochenschr. 2020. Vol.145, №12. P.844‒849 (in German). doi: 10.1055/a-1170-6061Hornuss D., Laubner K., Monasterio C., Thimme R., Wagner D. COVID-19 associated pneumonia despite repeatedly negative PCR-analysis from oropharyngeal swabs. Dtsch Med. Wochenschr. 2020; 145(12):844‒849 (in German). doi: 10.1055/a-1170-6061Lin C., Xiang J., Yan M., Li H., Huang S., Shen C. Comparison of throat swabs and sputum specimens for viral nucleic acid detection in 52 cases of novel coronavirus (SARS-Cov-2)-infected pneumonia (COVID-19) // Clin. Chem. Lab. Med. 2020. Vol.58, №7. P.1089‒1094. doi: 10.1515/cclm-2020-0187Lin C., Xiang J., Yan M., Li H., Huang S., Shen C. Comparison of throat swabs and sputum specimens for viral nucleic acid detection in 52 cases of novel coronavirus (SARS-Cov-2)-infected pneumonia (COVID-19). Clin. Chem. Lab. Med. 2020; 58(7):1089‒1094. doi: 10.1515/cclm-2020-0187Sivakorn C., Luvira V., Muangnoicharoen S., Piroonamornpun P., Ouppapong T., Mungaomklang A., Iamsirithaworn S. Case Report: Walking Pneumonia in Novel Coronavirus Disease (COVID-19): Mild Symptoms with Marked Abnormalities on Chest Imaging // Am. J. Trop. Med. Hyg. 2020. Vol.102, №5. P.940‒942. doi: 10.4269/ajtmh.20-0203Sivakorn C., Luvira V., Muangnoicharoen S., Piroonamornpun P., Ouppapong T., Mungaomklang A., Iamsirithaworn S. Case Report: Walking Pneumonia in Novel Coronavirus Disease (COVID-19): Mild Symptoms with Marked Abnormalities on Chest Imaging. Am. J. Trop. Med. Hyg. 2020; 102(5):940‒942. doi: 10.4269/ajtmh.20-0203Long C., Xu H., Shen Q., Zhang X., Fan B., Wang C., Zeng B., Li Z., Li X., Li H. Diagnosis of the Coronavirus disease (COVID-19): rRT-PCR or CT? // Eur. J. Radiol. 2020. Vol.126. Article number 108961. doi: 10.1016/j.ejrad.2020.108961Long C., Xu H., Shen Q., Zhang X., Fan B., Wang C., Zeng B., Li Z., Li X., Li H. Diagnosis of the Coronavirus disease (COVID-19): rRT-PCR or CT? Eur. J. Radiol. 2020; 126:108961. doi: 10.1016/j.ejrad.2020.108961Fang Y., Zhang H., Xie J., Lin M., Ying L., Pang P., Ji W. Sensitivity of Chest CT for COVID-19: Comparison to RT-PCR // Radiology. 2020. Vol.296, №2. E115‒E117. doi: 10.1148/radiol.2020200432Fang Y., Zhang H., Xie J., Lin M., Ying L., Pang P., Ji W. Sensitivity of Chest CT for COVID-19: Comparison to RT-PCR. Radiology 2020; 296(2):E115‒E117. doi: 10.1148/radiol.2020200432Fechner C., Strobel K., Treumann T., Sonderegger B,. Azzola A., Fornaro J., Schrading S., Roos J.E. COVID-19 and the role of imaging: early experiences in Central Switzerland // Swiss Med. Wkly. 2020. Vol.150. Article number w20304. doi: 10.4414/smw.2020.20304Fechner C., Strobel K., Treumann T., Sonderegger B., Azzola A., Fornaro J., Schrading S., Roos J.E. COVID-19 and the role of imaging: early experiences in Central Switzerland. Swiss Med. Wkly 2020; 150:w20304. doi: 10.4414/smw.2020.20304Zheng Z., Yao Z., Wu K., Zheng J. The diagnosis of pandemic coronavirus pneumonia: A review of radiology examination and laboratory test // J. Clin. Virol. 2020. Vol.128. Article number 104396. doi: 10.1016/j.jcv.2020.104396Zheng Z., Yao Z., Wu K., Zheng J. The diagnosis of pandemic coronavirus pneumonia: A review of radiology examination and laboratory test. J. Clin. Virol. 2020; 128:104396 doi: 10.1016/j.jcv.2020.104396Tenda E.D., Yulianti M., Asaf M.M., Yunus R.E., Septiyanti W., Wulani V., Pitoyo C.W., Rumende C.M., Setiati S. The Importance of Chest CT Scan in COVID-19 // Acta Med. Indones. 2020. Vol.52, №1. P.68‒73.Tenda E.D., Yulianti M., Asaf M.M., Yunus R.E., Septiyanti W., Wulani V., Pitoyo C.W., Rumende C.M., Setiati S. The Importance of Chest CT Scan in COVID-19. Acta Med. Indones. 2020; 52(1):68‒73.Ai T., Yang Z., Hou H., Zhan C., Chen C., Lv W., Tao Q., Sun Z., Xia L. Correlation of Chest CT and RT-PCR Testing for Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases // Radiology. 2020. Vol.296, №2. E32‒E40. doi: 10.1148/radiol.2020200642Ai T., Yang Z., Hou H., Zhan C., Chen C., Lv W., Tao Q., Sun Z., Xia L. Correlation of Chest CT and RT-PCR Testing for Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases. Radiology 2020; 296(2):E32‒E40. doi: 10.1148/radiol.2020200642Kang Z., Li X., Zhou S. Recommendation of low-dose CT in the detection and management of COVID-2019 // Eur. Radiol. 2020. Vol.30, №8. P.4356‒4357. doi: 10.1007/s00330-020-06809-6Kang Z., Li X., Zhou S. Recommendation of low-dose CT in the detection and management of COVID-2019. Eur. Radiol. 2020; 30(8):4356‒4357. doi: 10.1007/s00330-020-06809-6Kim H. Outbreak of novel coronavirus (COVID-19): What is the role of radiologists? // Eur. Radiol. 2020. Vol.30, №6. P.3266‒3267. doi: 10.1007/s00330-020-06748-2Kim H. Outbreak of novel coronavirus (COVID-19): What is the role of radiologists? Eur. Radiol. 2020; 30(6):3266‒3267. doi: 10.1007/s00330-020-06748-2

The authors declare that there are no conflicts of interest present.