Features of diagnostics and treatment of various plasmacytoma options
https://doi.org/10.36604/1998-5029-2023-88-105-119
Abstract
Aim. Demonstration of clinical cases of plasmacytoma, both solitary and one of the manifestations of multiple myeloma.
Materials and methods. A brief literature review on the diagnosis of bone and extramedullary plasmacytoma and clinical observations of various tumor options from the personal practice of the authors is presented.
Results. Two clinical observations of the primary diagnosis of solitary plasmacytoma are presented. In one case, there was a bone tumor, in the other − an extramedullary tumor. In both observations, a generalization of the process was subsequently noted. Three clinical cases of primary diagnosis of multiple myeloma accompanied by the development of plasmacytoma are also presented. In two cases, there was a lesion of the bone marrow, in one – a multiple-focal form of the disease. In two situations, a non-secreting variant of multiple myeloma was diagnosed. The features of diagnosis and treatment were analyzed.
Conclusion. In the diagnosis of focal forms of plasmacytoma (without lesions to the bone marrow and secretion), the leading role belongs to histological and immunohistochemical studies.
About the Authors
V. V. Voytsekhovskiy
Amur State Medical Academy
Russian Federation
Russian Federation
Valeriy V. Voytsekhovskiy, MD, PhD, DSc (Med.), Professor, Head of Department of Hospital Therapy with Pharmacology Course,
95 Gor'kogo Str., Blagoveshchensk, 675000
A. A. Grigorenko
Amur State Medical Academy;
Amur Regional Oncology Dispensary
Russian Federation
Russian Federation
Aleksey A. Grigorenko, MD, PhD, DSc (Med.), Professor, Head of Department of Morphology
95 Gor'kogo Str., Blagoveshchensk, 675000;
110 Oktyabrʹskaya Str., Blagoveshchensk, 675000
T. V. Esenina
Amur Regional Clinical Hospital
Russian Federation
Russian Federation
Tatiana V. Еsenina, MD, Head of Department of Hematology
26 Voronkova Str., Blagoveshchensk, 675028
S. N. Roshchin
Amur Regional Oncology Dispensary
Russian Federation
Russian Federation
Sergey N. Roshchin, MD, PhD (Med.), Morphologist, Department of Morphology
110 Oktyabrʹskaya Str., Blagoveshchensk, 675000
E. A. Filatova
Amur Regional Clinical Hospital
Russian Federation
Russian Federation
Ekaterina A. Filatova, MD, PhD (Med.), Hematologist of Department of Hematology
26 Voronkova Str., Blagoveshchensk, 675028
N. A. Fedorova
Amur Regional Clinical Hospital
Russian Federation
Russian Federation
Natalia А. Fedorova, MD, Hematologist of Department of Hematology
26 Voronkova Str., Blagoveshchensk, 675028
V. A. Krivutsa
Amur State Medical Academy
Russian Federation
Russian Federation
Vera А. Кrivutsa, 6th year student
95 Gor'kogo Str., Blagoveshchensk, 675000
Ya. D. Zueva
Amur State Medical Academy
Russian Federation
Russian Federation
Yana D. Zueva, 6th year student
95 Gor'kogo Str., Blagoveshchensk, 675000
M. V. Sayapina
Amur State Medical Academy
Russian Federation
Russian Federation
Maria V. Sayapina, 6th year student
95 Gor'kogo Str., Blagoveshchensk, 675000
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Review
For citations:
Voytsekhovskiy V.V., Grigorenko A.A., Esenina T.V., Roshchin S.N., Filatova E.A., Fedorova N.A., Krivutsa V.A., Zueva Ya.D., Sayapina M.V. Features of diagnostics and treatment of various plasmacytoma options. Bulletin Physiology and Pathology of Respiration. 2023;(88):105-119. (In Russ.) https://doi.org/10.36604/1998-5029-2023-88-105-119
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