Clinical observation of an infant with congenital stridor associated with intrauterine infection

Introduction. The frequency of occurrence of stridor or noisy breathing associated with obstruction of the upper respiratory tract in newborns and infants is increasing nowadays. The most common cause of stridor is a congenital pathology of laryngeal development – laryngomalacia. The severity of the clinical course of laryngomalacia and its prognosis depends on the anatomical variant of congenital pathology and the presence of congenital and acquired concomitant acquired comorbidities.
Aim. Demonstration of a clinical case of congenital stridor associated with intrauterine infection in an infant.
Results. An observation of a child with a severed clinical picture of stridor breathing from the age of 8 days, born from a mother with complicated obstetric anamnesis who had an infectious disease in early pregnancy; pathological childbirth (emergency c-section). The laryngomalacia type II with symptoms of laryngeal stenosis was detected in a child. The severity of the disease was due not only to the anatomical variant of the laryngeal malformation, but also to the presence of a combined congenital (heart disease, chest deformation) and acquired (perinatal encephalopathy) pathology. The presence of combined pathology in the child, apparently, is due to a single etiopathogenetic mechanism of intrauterine viral-bacterial infection, confirmed by the results of morphological examination of the placenta. The increase in respiratory failure required surgical intervention. Laser endoscopic supraglottoplasty completely stopped stridor breathing.
Conclusion. This observation illustrates the outcome of intrauterine infection as the development of a combined congenital and acquired pathology in a child; indicates the need for timely diagnosis and treatment of infectious diseases in women with complicated obstetric anamnesis. Early diagnosis, clarification of the cause of stridor in a child due to laryngeal malformations (laryngomalacia type II), successful surgical treatment allowed to fully restore the patency of the upper respiratory tract. 

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