MORPHOFUNCTIONAL STATE OF PLACENTA UNDER MYCOPLASMA INFECTION
https://doi.org/10.12737/article_5b9758eab95055.27382492
Abstract
Literature data on the ethiopathogenetic role of Ureaplasma species, Mycoplasma hominis in the development of premature delivery is contradictory due to the fact that Mycoplasma may be part of the normal microflora of women of reproductive age. The article is aimed to reveal the peculiarities of morphofunctional state of the placentas infected with Mycoplasma . The placentas were obtained from women whose pregnancy ended prematurely. Morphological, histological and molecular genetic study of 34 placentas from maternity patients with premature delivery was performed. Molecular genetic study was carried out by real-time PCR. Ureaplasma spp. was detected as a part of mono- and mixed infections in a concentration of 10*2 to 10*6 GE/mL in 32.3% of cases. Mycoplasma hominis was detected in 23.5% of cases, in a concentration of 10*3 to 10*6 GE/mL. Inflammatory changes in the membranes and placenta were revealed in all cases of Ureaplasma spp. detection as a monoinfection regardless of the degree of bacterial load, which confirms the belief about the pathogenetic role of Ureaplasma spp . in the process of reproductive disorders formation.
About the Authors
O. V. Ostrovskaya
Research Institute of Maternity and Childhood Protection
Russian Federation
Russian Federation
N. M. Ivakhnishina
Research Institute of Maternity and Childhood Protection
Russian Federation
Russian Federation
O. V. Kozharskaya
Perinatal Center of Khabarovsk Krai Ministry of Public Health
Russian Federation
Russian Federation
D. V. Musatov
Perinatal Center of Khabarovsk Krai Ministry of Public Health
Russian Federation
Russian Federation
V. G. Obukhova
Perinatal Center of Khabarovsk Krai Ministry of Public Health
Russian Federation
Russian Federation
M. A. Vlasova
Research Institute of Maternity and Childhood Protection
Russian Federation
Russian Federation
E. B. Nagovitsyna
Research Institute of Maternity and Childhood Protection
Russian Federation
Russian Federation
S. V. Suprun
Research Institute of Maternity and Childhood Protection
Russian Federation
Russian Federation
G. P. Evseeva
Research Institute of Maternity and Childhood Protection
Russian Federation
Russian Federation
O. A. Lebed’Ko
Research Institute of Maternity and Childhood Protection
Russian Federation
Russian Federation
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Review
For citations:
Ostrovskaya O.V., Ivakhnishina N.M., Kozharskaya O.V., Musatov D.V., Obukhova V.G., Vlasova M.A., Nagovitsyna E.B., Suprun S.V., Evseeva G.P., Lebed’Ko O.A. MORPHOFUNCTIONAL STATE OF PLACENTA UNDER MYCOPLASMA INFECTION. Bulletin Physiology and Pathology of Respiration. 2018;(69):43-49. (In Russ.) https://doi.org/10.12737/article_5b9758eab95055.27382492
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