PECULIARITIES OF MIXED RESPIRATORY VIRAL INFECTIONS IN WOMEN IN THE SECOND TRIMESTER OF PREGNANCY UNDER INTRAUTERINE INFECTION OF THEIR NEWBORNS WITH CEREBRAL ISCHEMIA

Clinical and serological features of the gestational process in 85 women with pregnancy, uncomplicated and complicated with parainfluenza-influenza infection in the second trimester of gestation, were studied. All examined women were divided into three groups. The first group (control) included 32 women with physiological course of pregnancy and their healthy full-term newborns. The second group included 32 patients with respiratory mixed-virus infection in the second trimester of gestation, and in their newborns there was diagnosed moderate cerebral ischemia and no signs of intrauterine infection. The third group included 21 women with respiratory mixed virus infection in the second trimester of pregnancy, which was the cause of antenatal infection in their full-term infants with cerebral ischemia of moderate severity. It was shown that the women of the third group compared with the second and first groups often complained of headache, photophobia, sweating and weakness, increase in body temperature to 37.6-38ºC, hoarseness of the voice, sore throat, as well as a prolonged course of acute nasopharyngitis and acute laryngitis. The above clinical features of acute respiratory viral infection in women in the second trimester of gestation may contribute to antenatal infection and may disrupt optimal conditions for intrauterine brain development in their babies.

respiratory viral infection, pregnancy, cerebral ischemia, intrauterine infection, newborn

1. Патент 1516980 СССР. Способ диагностики внутриутробной инфекции / О.А.Аксенов, З.А.Осипова, Г.П.Курбатова, В.Ф. Мельникова; опубл.23.10.89; Бюл. №39.

2. Гориков И.Н., Резник В.И. Состояние здоровья новорожденных и морфология плаценты при внутриутробной микст-вирусной респираторной инфекции // Дальневосточный журнал инфекционной. патологии. 2008. №12. С.48-52.

3. Грипп: руководство для врачей / под ред. Г.И.Карпухина. СПб: Гиппократ, 2001. 360 с.

4. Осидак Л.В., Дриневский В.П, Цыбалова Л.М. Ерофеева М.К., Жилинская И. Н., Образцова Е.В., Дондурей Е.А, Головачева Е.Г., Никоноров И. Ю. Острые респираторные инфекции у детей и подростков: практическое руководство для врачей / под ред. Л.В.Осидак. 2-е изд., доп. СПб.: ИнформМед, 2010. 216 с.

5. Резник В.И., Савосина Л.В., Лебедева Л.А., Исаева Н.В. Этиология эпидемий гриппа в Хабаровском крае // Дальневосточный журнал инфекционной патологии. 2006. №8. С.49-55.

6. Резник В.И., Перескокова М.А., Исаева Н.В., Лебедева Л.А., Савовина Л.В. Роль респираторных вирусов в этиологии ОРЗ негриппозной природы //Дальневосточный журнал инфекционной патологии. 2006. №8. С.55-57.