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Asthma as a manifestation of post-COVID syndrome

https://doi.org/10.36604/1998-5029-2025-95-126-134

Abstract

Introduction. One of the most common complications of the novel coronavirus infection (COVID-19) involves respiratory system disorders, particularly bronchial obstruction.

Aim. To highlight the importance of vigilance regarding the onset of respiratory diseases, including asthma, in the post-COVID period.

Results. This article describes a clinical case of newly diagnosed severe asthma in a 35-year-old patient following COVID-19. A notable feature of the patient’s condition was prolonged eosinophilia. Sensitization to inhalant allergens was ruled out by a negative Phadiatop ImmunoCAP screening test. Despite receiving a fixed triple combination of an inhaled corticosteroid, a long-acting β2agonist, and a long-acting anticholinergic agent, the patient’s disease remained uncontrolled with persistent airway obstruction. A genetically engineered biological therapy was subsequently prescribed, resulting in a marked clinical improvement.

Conclusion. This clinical case illustrates a manifestation of post-COVID syndrome—new-onset asthma. Timely diagnosis enables the prompt selection of appropriate therapy, improving the patient’s quality of life and facilitating a return to normal daily activities.  

About the Authors

I. V. Demko
Krasnoyarsk State Medical University; Krasnoyarsk Regional Clinical Hospital
Russian Federation

Irina V. Demko, MD, PhD, DSc (Med.), Professor, Head of Department of Hospital Therapy and Immunology with Postgraduate Education Course; Head of Pulmonary Allergology Сenter

1 Partizana Zheleznyaka Str., Krasnoyarsk, 660022

3 Partizana Zheleznyaka Str., Krasnoyarsk, 660022



K. I. Chinyakova
Krasnoyarsk State Medical University; Krasnoyarsk Regional Clinical Hospital
Russian Federation

Ksenia I. Chinyakova, MD, Postgraduate Student, Department of Hospital Therapy and Immunology with Postgraduate Education Course; Pulmonologist, Diagnostic and Treatment Department

1 Partizana Zheleznyaka Str., Krasnoyarsk, 660022

3 Partizana Zheleznyaka Str., Krasnoyarsk, 660022



A. Yu. Kraposhina
Krasnoyarsk State Medical University; Krasnoyarsk Regional Clinical Hospital
Russian Federation

Angelina Yu. Kraposhina, MD, PhD (Med.), Associate Professor, Associate Professor of Department of Hospital Therapy and Immunology with a Postgraduate Education Course; Pulmonologist of Department of Pulmonology

1 Partizana Zheleznyaka Str., Krasnoyarsk, 660022

3 Partizana Zheleznyaka Str., Krasnoyarsk, 660022



E. A. Sobko
Krasnoyarsk State Medical University; Krasnoyarsk Regional Clinical Hospital
Russian Federation

Elena A. Sobko, MD, PhD, DSc (Med.), Professor of the Department of Hospital Therapy and Immunology with a Postgraduate Course; Head of the Allergology Department

1 Partizana Zheleznyaka Str., Krasnoyarsk, 660022

3 Partizana Zheleznyaka Str., Krasnoyarsk, 660022



E. A. Bykhanova
Krasnoyarsk State Medical University
Russian Federation

Elena A. Bykhanova, MD, Resident of the Department of Hospital Therapy and Immunology with a Postgraduate Education Course

1 Partizana Zheleznyaka Str., Krasnoyarsk, 660022



O. S. Kruglova
Krasnoyarsk State Medical University
Russian Federation

Olga S. Kruglova, MD, Assistant of the Department of Hospital Therapy and Immunology with a Postgraduate Course

1 Partizana Zheleznyaka Str., Krasnoyarsk, 660022



E. S. Mineeva
Krasnoyarsk Regional Clinical Hospital
Russian Federation

Elena S. Mineeva, MD, Pulmonologist, Diagnostic and Treatment Department

3 Partizana Zheleznyaka Str., Krasnoyarsk, 660022



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For citations:


Demko I.V., Chinyakova K.I., Kraposhina A.Yu., Sobko E.A., Bykhanova E.A., Kruglova O.S., Mineeva E.S. Asthma as a manifestation of post-COVID syndrome. Bulletin Physiology and Pathology of Respiration. 2025;(95):126-134. (In Russ.) https://doi.org/10.36604/1998-5029-2025-95-126-134

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ISSN 1998-5029 (Print)