Respiratory viral infections and cold
https://doi.org/10.36604/1998-5029-2026-100-156-165
Abstract
Human viruses cause a wide range of respiratory diseases, from the common cold to pneumonia and severe acute respiratory syndrome. A key factor determining the outcome of the disease is the nature of the subject's innate immune response, which is influenced by various external factors, such as the virus encountered, the season of the year with prolonged exposure to low temperatures, endogenous factors such as the body's susceptibility to infection, existing chronic respiratory diseases, the severity of non-specific respiratory defense mechanisms, immunodeficiency states, and the expression of genes that increase vulnerability to both the underlying disease and viral invasion, as well as their upregulation against the background of local cooling of the respiratory tract. This review presents an analysis of scientific literature data on the prevalence, some antiviral defense mechanisms, and conditions of increased susceptibility to viral upper respiratory tract infections associated with cooling.
About the Authors
А. G. Prikhodko
Far Eastern Scientific Center of Physiology and Pathology of Respiration
Russian Federation
Russian Federation
Аnnа G. Prikhodko, MD, PhD (Med.), DSc (Med.), Main Staff Scientist, Laboratory of Functional Research of Respiratory System
22 Kalinina Str., Blagoveshchensk, 675000
J. M. Perelman
Far Eastern Scientific Center of Physiology and Pathology of Respiration
Russian Federation
Russian Federation
Juliy M. Perelman, MD, PhD (Med.), DSc (Med.), Corresponding Member of RAS, Professor, Head of Laboratory of Functional Research of Respiratory System
22 Kalinina Str., Blagoveshchensk, 675000
V. P. Kolosov
Far Eastern Scientific Center of Physiology and Pathology of Respiration
Russian Federation
Russian Federation
Victor P. Kolosov, MD, PhD (Med.), DSc (Med.), Academician of RAS, Professor, Main Staff Scientist, Laboratory of Functional Research of Respiratory System
22 Kalinina Str., Blagoveshchensk, 675000
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Prikhodko А.G., Perelman J.M., Kolosov V.P. Respiratory viral infections and cold. Bulletin Physiology and Pathology of Respiration. 2026;(100):156-165. (In Russ.) https://doi.org/10.36604/1998-5029-2026-100-156-165
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