Regulation by thiol disulfide and antioxidant systems of oxidative stress induced by atmospheric suspended particles
https://doi.org/10.36604/1998-5029-2019-73-112-124
Abstract
The review is devoted to the role of thioredoxin and glutathione antioxidant systems in protection of the body against oxidative stress caused by exposure to micro-sized solid suspended particles of atmospheric air. The features of components and parameters of solid suspended particles determining their oxidative properties have been described. The focus is on intracellular and molecular mechanisms affecting many antioxidant reactions. The issues of regulation, modulation and maintenance of cellular redox homeostasis by key reducing thiols have been considered.
About the Authors
L. S. Barskova
Vladivostok Branch of Far Eastern Scientific Center of Physiology and Pathology of Respiration - Research Institute of Medical Climatology and Rehabilitation Treatment
Russian Federation
Russian Federation
Lyudmila S. Barskova - Junior Staff Scientist, Laboratory of Medical Ecology and Recreational Resources.
73g Russkaya Str., Vladivostok, 690105
T. I. Vitkina
Vladivostok Branch of Far Eastern Scientific Center of Physiology and Pathology of Respiration - Research Institute of Medical Climatology and Rehabilitation Treatment
Russian Federation
Russian Federation
Tatyana I. Vitkina - PhD, D.Sc. (Biol.), Professor RAS, Head of Laboratory of Medical Ecology and Recreational Resources.
73g Russkaya Str., Vladivostok, 690105
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Barskova L.S., Vitkina T.I. Regulation by thiol disulfide and antioxidant systems of oxidative stress induced by atmospheric suspended particles. Bulletin Physiology and Pathology of Respiration. 2019;(73):112-124. (In Russ.) https://doi.org/10.36604/1998-5029-2019-73-112-124
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