THE CONDITION OF THE MUCOUS MEMBRANE OF THE NOSE AND PHARYNX IN PREGNANT WOMEN WITH CHRONIC SIMPLE BRONCHITIS IN REMISSION
https://doi.org/10.36604/1998-5029-2019-74-86-91
Abstract
Aim. To assess the condition of the nasal and pharyngeal mucosa in pregnant women with chronic simple bronchitis in remission. Materials and methods. A retrospective analysis of the results of anterior rhinoscopy, pharyngoscopy and examination of regional lymph nodes was performed in 100 women in the second trimester of pregnancy, uncomplicated and complicated by chronic simple bronchitis in remission. The first group consisted of 30 women with physiological pregnancy, the second hag 38 patients with chronic simple bronchitis without exacerbation, and the third included 32 women with chronic simple bronchitis in remission and clinical echographic signs of threatened miscarriage. Results. It was found out that patients of the first group, compared with the second and third ones, did not show hemorrhages on the mucous membrane of the posterior wall of the pharynx, had moderate hyperemia of the mucous membrane of the tonsils, their sclerosis and caseosis in the lacunae. In the third group compared to the second, in women there was increased the frequency of visualization of moderate edema of the nasal mucosa (p<0.05), pharynx (p<0.01) and soft palate (p<0.001), moderate hyperemia of the nasal mucosa (p<0.05), pharynx (p<0.01) and soft palate (p<0.01), single lymphoid granulations on the posterior wall of the pharynx (p<0.05), enlarged tonsils (p<0.01), edema of their mucosa (p<0.05), the expansion of lacunae (p<0.01), as well as the increase in mobile and painless occipital and submandibular lymph nodes (p<0.05). Conclusion. The above changes in the mucous membrane of the nose and pharynx, as well as the lymphoepithelial apparatus in chronic simple bronchitis without exacerbation indicate the important role of reducing the local immune protection of the upper respiratory tract in women in the pathogenesis of the threat of miscarriage.
About the Authors
I. N. Gorikov
Far Eastern Scientific Center of Physiology and Pathology of Respiration
Russian Federation
Russian Federation
MD, PhD (Med.), Senior Staff Scientist of Laboratory of Mechanisms of Etiopathogenesis and Recovery Processes of the Respiratory System at Non-Specific Lung Diseases
22 Kalinina Str., Blagoveshchensk, 675000, Russian Federation
V. P. Kolosov
Far Eastern Scientific Center of Physiology and Pathology of Respiration
Russian Federation
Russian Federation
Academician of RAS, MD, PhD, D.Sc. (Med.), Professor, Scientific Director
phone: 8-4162-77-28-00
22 Kalinina Str., Blagoveshchensk, 675000, Russian Federation
L. G. Nakhamchen
Far Eastern Scientific Center of Physiology and Pathology of Respiration
Russian Federation
Russian Federation
MD, PhD (Med.), Senior Staff Scientist of Laboratory of Functional Research of Respiratory System
22 Kalinina Str., Blagoveshchensk, 675000, Russian Federation
A. N. Odireev
Far Eastern Scientific Center of Physiology and Pathology of Respiration
Russian Federation
Russian Federation
MD, PhD, D.Sc. (Med.), Head of Laboratory of Prophylaxis of Non-Specific Lung Diseases
22 Kalinina Str., Blagoveshchensk, 675000, Russian Federation
I. A. Andrievskaya
Far Eastern Scientific Center of Physiology and Pathology of Respiration
Russian Federation
Russian Federation
PhD, D.Sc. (Biol.), Professor RAS, Head of Laboratory of Mechanisms of Etiopathogenesis and Recovery Processes of the Respiratory System at Non-Specific Lung Diseases
22 Kalinina Str., Blagoveshchensk, 675000, Russian Federation
A. F. Popov
Pacific State Medical University
Russian Federation
Russian Federation
MD, PhD, D.Sc. (Med.), Professor, Department of Infectious Diseases
2 Ostryakova Ave., Vladivostok, 690002, Russian Federation
A. A. Sergievich
Far Eastern Federal University
Russian Federation
Russian Federation
PhD (Biol.), Deputy Vice Rector for Research
8 Sukhanova Str., Vladivostok, 690950, Russian Federation
T. A. Batalova
Amur State Medical Academy
Russian Federation
Russian Federation
PhD, D.Sc. (Biol.), Associate Professor, Head of Department of Physiology and Pathophysiology
95 Gor'kogo Str., Blagoveshchensk, 675000, Russian Federation
E. A. Borodin
Amur State Medical Academy
Russian Federation
Russian Federation
MD, PhD, D.Sc. (Med.), Professor, Head of Department of Biochemistry
95 Gor'kogo Str., Blagoveshchensk, 675000, Russian Federation
E. S. Lobanova
Amur State Medical Academy
Russian Federation
Russian Federation
6th year Student of Medical Faculty
95 Gor'kogo Str., Blagoveshchensk, 675000, Russian Federation
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Review
For citations:
Gorikov I.N., Kolosov V.P., Nakhamchen L.G., Odireev A.N., Andrievskaya I.A., Popov A.F., Sergievich A.A., Batalova T.A., Borodin E.A., Lobanova E.S. THE CONDITION OF THE MUCOUS MEMBRANE OF THE NOSE AND PHARYNX IN PREGNANT WOMEN WITH CHRONIC SIMPLE BRONCHITIS IN REMISSION. Bulletin Physiology and Pathology of Respiration. 2019;(74):86-91. (In Russ.) https://doi.org/10.36604/1998-5029-2019-74-86-91
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