CLINICAL AND FUNCTIONAL PECULIARITIES OF BRONCHIAL ASTHMA CLINCIAL COURSE COMBINED WITH POLYPOUS RHYNOSINUSITIS AT DIFFERENT VARIANTS OF TREATMENT
Abstract
111 patients with bronchial asthma (BA) including 25 patients without upper airways pathology and 86 patients with concomitant chronic polypous rhynosinusitis (CPRS) were examined. All patients went through the study of ventilation pulmonary function, the measurement of nasal resistance, bronchial challenge with cold air, registration of the expired air temperature. Against the base therapy in 40 BA patients with concomitant CPRS the polyps were ablated, 46 patients had a combined treatment of CPRS with application of intranasal inhalations of corticosteroids and laser therapy. It is established that the application of intranasal inhalations of beclometasone and laser irradiation combined with standard base therapy allows to improve BA clinical course, restore the patency and conditioning capacity of the nose and decrease the level of cold airway hyperresponsiveness. The mentioned therapy leads to regress of polypous tissue in nose and paranasal sinuses and significantly decreases the probability of CPRS relapses.
Keywords
bronchial asthma,
polypous rhynosinusitis,
corticosteroids,
laser therapy,
cold airway hyperresponsiveness
УДК 612.225[616.211-006.5+616.248]
About the Authors
Ella V. Zakharova
FAR EASTERN SCIENCE CENTRE PHYSIOLOGY AND PATHOLOGY OF RESPIRATION
Russian Federation
Russian Federation
Владимир Самсонов
Дальневосточный научный центр физиологии и патологии дыхания СО РАМН
Russian Federation
Russian Federation
References
1. Биличенко Т.Н. Эпидемиология бронхиальной астмы // Бронхиальная астма / под ред. А.Г.Чучалина. М.: Агар, 1997. Т.1. С.400-423.
2. Глобальная стратегия лечения и профилактики бронхиальной астмы / под ред. А.Г.Чучалина.- М.: Атмосфера, 2002. 160 с.
3. Демичева, Е.В. Применение внутривенного лазерного облучения крови в комплексном лечении больных хроническими обструктивными заболеваниями легких: автореф. дис. … канд. мед. наук. М., 1991. 21 с.
4. Приходько А.Г., Перельман Ю.М. Холодовая реактивность дыхательных путей у больных хроническим бронхитом // Пульмонология. 2003. № 3. С.24-28.
5. Чучалин, А.Г. Бронхиальная астма и астмаподобные состояния // Рус. мед. журн. 2002. Т.10, №5. С.232-235.
6. Bosquet J. Management of chronic respiratory and allergic diseases in developing countries. Focus on sub-Saharan Africa // Allergy. 2003. Vol.58, №4. P.265-283.
7. Brown B.L. Nasal polypectomy in patients with asthma and sensitivity to aspirin // Arch. Otolaryngol. 1979. Vol.105. P.413-416.
8. Dursun A.B. Clinical aspects of the link between chronic sinonasal diseases and asthma // Allergy Asthma Proc. 2006. Vol.27, №6. P.510-515.
9. Global Initiative for Asthma: Global strategy for asthma management and prevention: Revised 2006 [Electronic resource] / Global Initiative for Asthma. 2006. URL: <http://www.ginasthma.org>.
10. Jankowski R. Incidence of medico-surgical treatment for nasal polyps on the development of associated asthma // Rhinology. 1992. Vol.30. P.249-258.
11. Lamblin C. Long-term follow-up of pulmonary function in patients with nasal polyposis // Am. J. Respir. Crit. Care Med. 2000. Vol.161. P.406-413.
Review
For citations:
Zakharova E.V., CLINICAL AND FUNCTIONAL PECULIARITIES OF BRONCHIAL ASTHMA CLINCIAL COURSE COMBINED WITH POLYPOUS RHYNOSINUSITIS AT DIFFERENT VARIANTS OF TREATMENT. Bulletin Physiology and Pathology of Respiration. 2010;(38):24-28. (In Russ.)
Views:
160
Email this article 