SIGNIFICANCE OF PROCALCITONIN AND CYTOKINES IN PREDICTION OF A COMPLICATED COURSE OF COMMINITY-ACQUIRED PNEUMONIA
Abstract
The contents of biomarkers of activity of inflammatory process (IL-6, IL-2, TNF-б, C-reactive protein and procalcitonin) with the further estimation of their diagnostic significance have been studied in patients with community-acquired pneumonia of different severity, complicated course, and lethal outcome. Diagnostic sensitivity and specificity of the mentioned markers of inflammation have been assessed. The complex of predictors for prognostication of community-acquired pneumonia complicated clinical course and lethal outcome with has been suggested. The ways to prognosticate a complicated course of community-acquired pneumonia at the early hospitalization of the patient have been developed.
About the Authors
Ekaterina Yu. Kochegarova
FAR EASTERN SCIENCE CENTRE PHYSIOLOGY AND PATHOLOGY OF RESPIRATION
Russian Federation
Russian Federation
Виктор Колосов
Дальневосточный научный центр физиологии и патологии дыхания Сибирского отделения РАМН, Благовещенск
Russian Federation
Russian Federation
References
1. Гельцер Б.И., Проселкова Е.В. Система цитокинов и болезни органов дыхания. Владивосток, 2005. 320 с.
2. Прокальцитонин - новый показатель в диагностике тяжелой инфекции / Васильев А.В. [и др.] // Украiн. Мед. Час. 2001. №4 (24). С.129-137.
3. Флетчер Р.Ф., Вагнер Э. Клиническая эпидемиология. Основы доказательной медицины: пер. с англ. М.: Медиа Сфера, 1998. 352 с.
4. Внебольничная пневмония у взрослых. Практические рекомендации по диагностике, лечению и профилактике: пособие для врачей / Чучалин А.Г. [и др.]. Смоленск: MAKMAX, 2010. 80 с.
5. Gendrel D., Bohuon C. Procalcitonin as marker of bacterial infection // Pediatr. Infect. Dis. J. 2003. Vol.19. P.679-688.
Review
For citations:
Kochegarova E.Yu., SIGNIFICANCE OF PROCALCITONIN AND CYTOKINES IN PREDICTION OF A COMPLICATED COURSE OF COMMINITY-ACQUIRED PNEUMONIA. Bulletin Physiology and Pathology of Respiration. 2011;(40):48-51. (In Russ.)
Views:
146
Email this article 