ROLE OF INTRA- AND EXTRACARDIAC FACTORS IN THE DEVELOPMENT OF VENOUS CONGESTION IN THE LIVER AT CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Abstract

The influence of pulmonary and intracardiac hemodynamics disturbance and of respiration biomechanics on the development of venous congestion in the liver at chronic obstructive pulmonary disease was studied. The disturbances of venous blood flow in the liver at the initial phase of a disease can be caused by extracardiac reasons. The disease progressiveness leads to the development of pulmonary hypertension and to the disturbance of diastolic and systolic function of the right ventricle, which causes congestion. At the reduction of contractile capacity of the right ventricle myocardium, the influence of respiration mechanisms on the character of venous return becomes weaker.