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FEATURES OF alpha-LINOLENIC ACID METABOLISM IN PREGNANCY COMPLICATED BY HERPES-VIRUS INFECTION

Abstract

The features of alpha-linolenic acid metabolism in the peripheral blood of pregnant women of III trimester and in the homogenate of placentas of parturient women with the exacerbation of herpes-virus infection depending on IgG antibodies titer to the virus of simple herpes of 1 type have been studied in this work. It was found out that pregnant women who suffered from the exacerbation of herpes-virus infection during gestation had a decrease of alpha-linolenic acid concentration in plasma of the peripheral blood by 35% and in membranes of erythrocytes by 42%. At the same time in the homogenate of placentas of the parturient women who suffered from the exacerbation of herpes-virus infection during pregnancy there was a decrease of alpha-linolenic acid content. The most significant changes were observed at IgG antibodies titer to the virus of simple herpes of 1 type 1:12800. The revealed dysbolism of alpha-linolenic acid in herpes-virus infection may lead to a poor production of protective eicosanoids synthesized from acids of omega-3 family.

Keywords


618.3-06:616.523:577.123

About the Author

Nataliyа A. Ishutina
Far Eastern Scientific Center of Physiology and Pathology of Respiration of Siberian Branch RAMS
Russian Federation


References

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Review

For citations:

Ishutina N.A. FEATURES OF alpha-LINOLENIC ACID METABOLISM IN PREGNANCY COMPLICATED BY HERPES-VIRUS INFECTION. Bulletin Physiology and Pathology of Respiration. 2012;(44):66-68.

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