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FEATURES OF LIPID METABOLISM AT GENERAL COOLING OF THE ORGANISM

Abstract

Free fatty acids take an active part in the thermogenesis of the organism. It is known that three-hour cooling of man's organism leads to the growth of free fatty acids in blood plasma by 30 %. The aim of the research is to determine the character of phospholipids and fatty acids metabolism in the peripheral blood of experimental animals at general cooling of the organism. It is established that at cooling of rabbits during three hours at temperature -30ºС there is a significant increase of lysophosphatidylcholine in the peripheral blood till 3.0±0.2% (control - 0.4±0.05%). The quantity of fatty acids at animals cooling increases till 5.5±1.2% during three hours, and by the 30th day of the experiment till 6.6±1.3%. The quantity of arachidonic acid in the peripheral blood of rabbits by the 30th day of the experiment increases till 6.3±1.4% (control - 2.5±0.3%). So, long cooling of the organism at temperature -30ºС results in the disturbance of lipid metabolism which is accompanied by the growth of eicosanoids, lysophosphatidylcholine and arachidonic acid in the peripheral blood.

About the Author

Mikhail M. Lutsenko
Far Eastern Scientific Center of Physiology and Pathology of Respiration SB RAMS
Russian Federation


References

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Review

For citations:

Lutsenko M.M. FEATURES OF LIPID METABOLISM AT GENERAL COOLING OF THE ORGANISM. Bulletin Physiology and Pathology of Respiration. 2012;(44):95-100.

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