THE INFLUENCE OF THE ACUTE FORM OF CHRONIC NON-OBSTRUCTIVE AND OBSTRUCTIVE BRONCHITIS OF VIRUS ETIOLOGY IN WOMEN IN II TRIMESTER OF PREGANCY ON THE STATE OF CEREBRAL BLOODFLOW IN THEIR NEWBORN

Abstract

The state of cerebral blood flow in 44 children of the early neonatal age with the cerebral ischemia of the first degree born from mothers who had an acute form of chronic bronchitis of a virus genesis in the second trimester of pregnancy was studied. All babies were divided into two groups: the first group included 21 newborns whose mothers suffered the acute form of chronic non-obstructive bronchitis, and the second group consisted of 23 babies whose mothers had an acute form of chronic obstructive bronchitis. A complex serological, biochemical, functional and clinical research was done. It was found out that newborns of the second group in comparison with those from the first group oftener had an intrauterine infecting with А(Н3N2) influenza virus that plays a significant role in endotoxemia and brain blood vessels affection. Against the antenatal respiratory virus infection in babies of the second group in comparison with those from the second group higher indicators of mean molecular peptides (0.30±0.005 and 0.28±0.005 units of optical density, respectively, р<0.01) were registered in blood plasma. While studying the vascular resistance, the resistance index of mean brain artery in babies of the second group exceeded the values of those from the first group (0.76±0.015 and 0.71±0.013 standard units, respectively, р<0.05). More intensive clinical syndromes of hyperexcitability and motional dysfunctions were registered in the newborns of the second group.