CHANGE OF BLOOD FLOW IN UTERINE ARTERIES AND CHORION ECHOSTRUCTURE AT CHRONIC CYTOMEGALOVIRUS INFECTION IN WOMEN IN THE FIRST TRIMESTER OF PREGNANCY

Abstract

To study the changes in the blood flow and chorion echostructure at cytomegalovirus infection in women in the I trimester of pregnancy there were examined 150 pregnant women with latent course and activation of chronic cytomegalovirus infection against latent chronic herpetic infection (virus of the simple herpes of I type) (the main group) and 48 women with physiologic course of pregnancy who under immune-enzyme analysis did not have specific IgG и IgМ to cytomegalovirus (the control group). It was found out that the women with activation of chronic cytomegalovirus infection which was confirmed by detection of specific IgM to cytomegalovirus and of titer of specific IgG to cytomegalovirus infection (1:400-1:600) in comparison with the control group had an increase of the vessel resistance in the uterine arteries as well as of the frequency of detection of uterus hypertonus, the thickening, the thinning and low localization of chorion, retroplacental hematoma, deformation of fetal ovum and dead pregnancy. The patients with activation of chronic cytomegalovirus infection (the presence of IgM to cytomegalovirus and 4 times growth of IgG to cytomegalovirus 1:200-1:800) in comparison with the women with activation of chronic cytomegalovirus infection (the presence of IgM at the absence of 4 times growth of IgG to cytomegalovirus) have higher parameters of systole-diastolic correlation in the right and left uterine arteries as well as more frequent chorion thinning and dead pregnancy.