POLYRHEOCARDIOGRAPHY DIAGNOSTIC POTENTIAL AT CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Abstract

The purpose of this study was to evaluate the hemodynamics of central and lung hemodynamics in patients with chronic obstructive pulmonary disease (COPD) with the method of computer-aided polyrheocardiography. The study involved 51 patients with COPD of mild to moderate severity in remission and without a concomitant cardiovascular disease. In the first group there were 22 patients with mild COPD; the second one comprised 29 patients with COPD of moderate severity. COPD diagnosis was carried out in accordance with the GOLD 2011. The control group consisted of 20 healthy non-smoking volunteers. The study of central hemodynamics in both groups showed the prevalence of hypokinetic type in 63% of cases; the normokinetic type was detected in 26% and hyperkinetic type in 11% of cases. Hemodynamic changes in the lung circulation were characterized by the increase of systolic pulmonary artery pressure by 40% in patients with mild COPD, and it was twice as much (p<0.01) in patients with moderate COPD compared with the control group, and by the increase of final diastolic blood pressure in the pulmonary artery in 65% and 4.5 times as much (p<0.01), respectively. Thus, the method of computer-aided polyrheocardiography allows to diagnose pulmonary hypertension in patients with COPD even before the development of intensive bronchoobstructive changes.