ABOUT OPTIMIZATION OF TREATMENT OF ACUTE MAXILLARY SINUSITIS

Abstract

The aim of the research is to study the influence of intrasinusoidal electrophoresis of Talay mineral water on the state of the local immunity and to estimate the clinical effectiveness of this method at the treatment of patients with acute maxillary sinusitis. 68 patients were examined and 38 patients after the lavage of maxillary sinusitis went through intrasinusoidal electrophoresis with nitrogen low-mineral chloride hydrocarbonate-sodium water with a big quantity of silicic acid and fluorine. The lavage and the introduction of aqueous solution of antibiotics of the second generation Cefazolinum group were done to 30 patients (the control group) into maxillary sinuses. All the patients got the standard antibacterial and antihistaminic therapy. The parameters of the local immunity of the nose mucous tunic were studied in the lavages from the maxillary sinuses of all the participants of the study with the immune-enzyme analysis. It was found out that the patients of the main group had an earlier statistically reliable (р<0.05) positive dynamics of clinical symptoms and roentgenologic signs of the disease; a bed day also decreases (р<0.05). The differences in the local immune system responsiveness of the patients of the main and control groups were defined. In the lavage from the maxillary sinuses the patients of the main group were found to have the decrease of secretory sIgA in comparison with the initial values by 48.7%, of IgE by 75.7%, whereas the patients of the control group had the decrease by 21.3 and 32.2%, respectively, which proves a more adequate reduction of the local inflammation under the application of electrophoresis of mineral water. In the main group the number of disrupt phagocytes decreased in comparison with the initial values by 50.4% and the number of neutrophils by 11.3%, at the same time in the control group it was by 10.1 and 2.4%, respectively. So, the complex treatment of patients with the acute sinusitis with the application of intrasinusoid electrophoresis of mineral water leads to an early reduction of clinical symptoms and an intensive and anti-edema, anti-inflammatory and immune-modulating effect, which allows to improve the treatment of the patients with acute purulent maxillary sinusitis and contributes to a faster sanation of purulent inflammation.