INFLUENCE OF INTRAUTERINE PARAINFLUENZA AND MIXED-RESPIRATORY VIRUS INFECTION UNDER MODERATE CEREBRAL ISCHEMIA ON NEUROSONOGRAPHIC PICTURE AND BLOOD SUPPLY OF THE BRAIN IN NEWBORNS

The study of the brain echostructure and blood flow in the medial cerebral artery under moderate cerebral ischemia was done in 29 newborns with intrauterine parainfluenza of 1 and 3 types (group II) and in 26 children with moderate cerebral ischemia (group III) diagnosed against intrauterine mixed-respiratory virus infection (parainfluenza and influenza B were diagnosed in 5 newborns, parainfluenza and respiratory-syncytial virus in 9 newborns, parainfluenza and adenovirus in 12 babies). In group I (the control group) there were 30 healthy newborns. It was found out that in group II the babies had the signs of cerebral edema (44.8%), periventricular ischemia (27.6%), the widening of lateral ventricles and subarachnoid cavity (6.9%), choroid plexus cyst and intraventricular hemorrhaging of I degree (3.4%), brain immaturity (6.9%). These signs of disorder of brain development and blood supply were not found in healthy newborns. The babies of group II in comparison with newborns of group I didn’t have changes in the value of the vessel resistance in the medial cerebral artery; the values of resistance index were 0.68±0.03 and 0.67±0.02, respectively (р>0.05). In newborns of group III in comparison with the babies from group II the signs of brain immaturity (34.6%, р<0.05) and intraventricular hemorrhaging (30.8%, р<0.05) were diagnosed oftener; there was also a higher vessel resistance in the medial cerebral artery (the values of resistance index were 0.77±0.03, р<0.05) against more intensified antenatal hypoxia and endotoxemia which negatively influence endothelium of cerebral blood vessels.

новорожденные, церебральная ишемия, нейросонография, кровоснабжение головного мозга, внутриутробный парагрипп, внутриутробная микст-респираторная вирусная инфекция, newborns, cerebral ischemia, neurosonography, cerebral blood supply, intrauterine parainfluenza, intrauterine mixed-respiratory virus infection

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