INFORMATIVENESS OF SPIROMETRY IN DIAGNOSTICS OF AIRWAY MECHANICS DISORDER IN PATIENTS WITH INTERSTITIAL LUNG DISEASES
Abstract
Spirometry, body plethysmography and elastic features of lungs examined with the esophageal probe were analyzed in 590 patients with interstitial lung diseases. Spirometry was informative for obstructive symptoms recognition in patients with interstitial lung disease. In 80% of cases decreased Tiffeneau test and normal vital capacity corresponded to obstructive disorders which were confirmed by a comprehensive examination. At the same time, spirometry was not informative in detecting restrictive syndrome as the spirometry tests were not normal only in 52% of patients with this variant of ventilation disorders. In the diagnosis of mixed disorders the predictive ability of spirometry was even lower: the simultaneous decrease of vital capacity and Tiffeneau test were found only in 37% of cases of mixed pattern.
About the Authors
Marina Yu. Kameneva
Pavlov First Saint Petersburg State Medical University
Russian Federation
Russian Federation
Vasiliy I. Trofimov
Pavlov First Saint Petersburg State Medical University
Russian Federation
Russian Federation
Artem V. Tishkov
Pavlov First Saint Petersburg State Medical University
Russian Federation
Russian Federation
References
1. Св. 2014620056 РФ. База данных интерстициальных заболеваний легких / М.Ю.Каменева, В.И.Трофимов, А.В.Тишков; опубл. 20.02.2014.
2. Каменева М.Ю. Оценка эффективности различных способов определения нормальных значений параметров механики дыхания при диагностике рестриктивного типа вентиляционных нарушений // Рос. семейный врач. 2014. Т.18. №2. С.24-28.
3. Cryptogenic fibrosing alveolitis with preserved lung volumes / M.J.Doherty [et al.] // Thorax. 1997. Vol.52, №11. P.998-1002.
4. European Community for Steel and Coal: standardized lung function testing // Eur. Respir. J. 1993. Vol.6, Suppl.16. P.5-40.
5. Conditions associated with an abnormal nonspecific pattern of pulmonary function tests / R.E.Hyatt [et al.] // Chest. 2009. Vol.135, №2. P.419-424.
6. The nonspecific pulmonary function test. Longitudinal follow-up and outcomes / V.N.Iyer [et al.] // Chest. 2011. Vol.139, №4. P.878-886.
7. Interpretative strategies for lung function tests / R. Pellegrino [et al.] // Eur. Respir. J. 2005. Vol.26, №5. P.948-968.
8. Measurement of FEF25-75% and FEF75% does not contribute to clinical decision making / P.H.Quanjer [et al.] // Eur. Respir. J. 2014. Vol.43, №4. P.1051-1058.
9. Wesotowski S., Boros P. Restrictive pattern in spirometry. Does FEV1/FVC need to be increased? // Pneumonol. Alergol. Pol. 2011. Vol.79, №6. P.382-387.
Review
For citations:
Kameneva M.Yu., Trofimov V.I., Tishkov A.V. INFORMATIVENESS OF SPIROMETRY IN DIAGNOSTICS OF AIRWAY MECHANICS DISORDER IN PATIENTS WITH INTERSTITIAL LUNG DISEASES. Bulletin Physiology and Pathology of Respiration. 2015;(55):8-14. (In Russ.)
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