PHYTOPREPARATIONS IN PROPHYLAXIS OF RESPIRATORY DISEASES IN CHILDREN

In conditions of the educational institution 4 groups of children (at the age of 13-14 years old) were examined; each group consisted of 15 children. In the first group the prophylaxis was carried out by the application of eleutherococcus extract at one drop per life year a day during 28 days, in the second group rhodiola rosea extract was applied (1 drop per life year, 28 days), in the third group the children took hypericum tincture 10 ml per life year during 28 days, the fourth group was the control one (phytopreparations prophylaxis was not applied). The sanitation course was held during autumn-and-winter period (November, January). After the experiment ended the children’s attendance in every group was observed and the content of lipid peroxidation products against major constituents of antioxidant system in children’s blood plasma was studied. The research results showed that in the first and the third groups the number of children with poor attendance was significantly smaller as compared with the control group. Consequently, the possibility of application of eleutherococcus and hypericum in prophylaxis of respiratory apparatus diseases among children of adulthood is proved. The examination of the content of lipid peroxidation products in children’s blood plasma showed that the application of phytopreparations causes the significant decrease of lipid hydroperoxides content in blood plasma of children taking rhodiola and hypericum (by 27.7% and 24.1%, respectively, as compared with the control group). The content of malonic dialdehyde in blood plasma of all experimental groups is lower than in the control group: in the group where eleutherococcus was applied by 12.1%, rhodiola rosea by 17.3%, hypericum by 10.4%. The content of diene conjugates in groups where phytopreparations were applied is lower than in the control group: in the group where eleutherococcus was applied by 13.3%, rhodiola rosea by 38.8%, hypericum by 28.7%. The content of major constituents of the antioxidant system in blood plasma of children who took phytopreparations is higher in all experimental groups as compared with the control group. The experiment results show that the application of phytopreparations leads to the decrease of process intensity of peroxidation by means of decrease of the content of major constituents of lipid peroxidation - lipid hydroperoxides, diene conjugates, and malonic dialdehyde. For reasons given, it can be stated that one of the reserves of disease incidence decrease in educational institutions is directed sanitation of children with the application of phytopreparations.

дети, заболевания органов дыхания, фитопрепараты, элеутерококк, зверобой, родиола розовая, продукты пероксидации (гидроперекиси липидов, диеновые конъюгаты, малоновый диальдегид), антиоксидантная система, children, respiratory diseases, phytopreparations, eleutherococcus, hypericum, rhodiola rosea, products of peroxidation (lipid hydroperoxides, diene conjugates, malonic dialdehyde), antioxidant system

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