MORPHOFUNCTIONAL CHARACTERISTIC OF MUCUS-PRODUCING COMPONENTS IN RATS AIRWAYS UNDER OSMOTIC STRESS
Abstract
Morphological and morphometric characteristics of epithelial cells of the mucous membrane of the trachea in laboratory animals exposed to experimental osmotic stress were studied. The height of the epithelial layer of intact rats under the influence of inhaled air of 100% humidity was measured. The qualitative histological and electronic microscopic studies of compensatory-adaptive reactions of epithelial cells of the mucous membrane of the trachea of rats were done. It was found out that under distilled water ultrasonic inhalation epithelial cells (ciliated and goblet) of the epithelial layer expand, which results in the increase of epithelial height and the occurrence of edema in the submucosa. There is an expansion of intercellular space of the epithelial layer of the mucous membrane of the trachea. Subsequently, mast cells penetrate into the intercellular space; it promotes the inflammation of airways.
About the Authors
Sergey S. Tseluyko
Amur State Medical Academy
Russian Federation
Russian Federation
Dmitriy S. Semenov
Amur State Medical Academy; Far Eastern Scientific Center of Physiology and Pathology of Respiration
Russian Federation
Russian Federation
Juliy M. Perelman
Far Eastern Scientific Center of Physiology and Pathology of Respiration
Russian Federation
Russian Federation
Andrey N. Odireev
Far Eastern Scientific Center of Physiology and Pathology of Respiration
Russian Federation
Russian Federation
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Review
For citations:
Tseluyko S.S., Semenov D.S., Perelman J.M., Odireev A.N. MORPHOFUNCTIONAL CHARACTERISTIC OF MUCUS-PRODUCING COMPONENTS IN RATS AIRWAYS UNDER OSMOTIC STRESS. Bulletin Physiology and Pathology of Respiration. 2015;(57):70-76. (In Russ.)
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