INTERRELATION OF INDICATORS OF THE FUNCTIONAL STATE OF THE DIAPHRAGM AND PULMONARY HEMODYNAMICS IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE

The aim of the study was to study the correlation between the indices of the functional state of the diaphragm and pulmonary hemodynamics in COPD patients at different stages of chronic pulmonary heart (CPH). 79 patients with COPD were examined. Patients were divided into 2 groups, taking into account the pulmonary artery pressure and the presence of clinical signs of right ventricular failure. The first group included 40 COPD patients complicated by compensated CPH; the second group included 39 patients with decompensated CPH. A complex examination of intracardiac hemodynamics and functional state of the diaphragm was carried out at the XD-11 XE device PHILIPS (USA). The following results were obtained: in patients with compensated CPH there was an increase in the thickness of the diaphragm, a decrease in the diaphragm mobility during tidal and forced breathing, and an increase in the rate of contraction of the diaphragm during tidal and forced breathing. Patients with decompensated CPH were found to have an increase in the thickness of the diaphragm, a sharp decrease in the diaphragm excursion during tidal and forced breathing, a decrease in the fraction of thickening of the muscular part of the diaphragm. The correlation analysis revealed the most informative ultrasound indices of the impairment of the functional state of the diaphragm in patients with COPD, significantly associated with pulmonary hemodynamic indices: diaphragm excursion during tidal and forced breathing, relaxation rate of the diaphragm muscle, thickness and fraction of thickening of the muscular part of the diaphragm. Determination of the functional state of the diaphragm in patients with COPD allows an early detection of signs of respiratory muscle dysfunction, a timely appointment of corrective therapy, and prevention of the development and progression of pulmonary-cardiac failure.

chronic obstructive pulmonary disease, chronic pulmonary heart, functional state of diaphragm, pulmonary hemodynamics

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