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Non-gestational ovarian choriocarcinoma (a clinical case)

https://doi.org/10.36604/1998-5029-2024-92-93-99

Abstract

Non-gestational ovarian choriocarcinoma is an exceptionally rare malignant germ cell tumor characterized by a particularly aggressive course, difficult diagnosis, and the inability to predict outcomes at the early stages of the disease. Objective: To draw the attention to the possibility of pure non-gestational ovarian choriocarcinoma mimicking an ectopic ovarian pregnancy. We present the case history of a patient with diagnosed non-gestational ovarian choriocarcinoma mimicking ectopic pregnancy, recorded in the 3rd gynecological department of the State Budgetary Healthcare Institution of the Republic of Mordovia "Republican Clinical Hospital № 4" (Saransk). Our clinical observation adds to the already known information about this rare disease and, thus, we hope that the information provided will be an additional reason to increase the level of medical vigilance in terms of diagnosis of this disease.

About the Authors

Y. A. Kovaleva
Federal State Budgetary Educational Institution of Higher Education «National Research Ogarev Mordovia State University»
Russian Federation

Yulia A. Kovaleva, 6th year student

68 Bolshevistskaya Str., Saransk, 430005



A. S. Nechaykin
Federal State Budgetary Educational Institution of Higher Education «National Research Ogarev Mordovia State University»
Russian Federation

Andrey S. Nechaykin, PhD (Med.), Associate Professor, Associate Professor of the Department of Obstetrics and Gynecology named after Professor A.P. Marusov

68 Bolshevistskaya Str., Saransk, 430005



S. V. Abramova
Federal State Budgetary Educational Institution of Higher Education «National Research Ogarev Mordovia State University»
Russian Federation

Svetlana V. Abramova, PhD (Med.), Associate Professor, Head of the Department of Obstetrics and Gynecology named after Professor A.P. Marusov

68 Bolshevistskaya Str., Saransk, 430005



M. V. Labzina
Federal State Budgetary Educational Institution of Higher Education «National Research Ogarev Mordovia State University»
Russian Federation

Margarita V. Labzina, PhD (Med.), Associate Professor, Associate Professor of the Department of Obstetrics and Gynecology named after Professor A.P. Marusov

68 Bolshevistskaya Str., Saransk, 430005



References

1. Savel'yeva G.M., Sukhikh G.T., Serov V.N., Radzinskiy V.E., Manukhin I.B., editors. [Gynecology: a national guideline. Concise edition]. Moscow: GEOTAR-Media; 2020 (in Russian). https://doi.org/10.33029/9704-5739-9-GIN-2020-1-056

2. Trishin V.M., Sergeyeva I.V., Gorgidzhanyan R.S., Kira K.Ye. Non-gestational choriocarcinoma of the ovary: a case report. Vestnik Natsional'nogo mediko-khirurgicheskogo Tsentra im. N.I. Pirogova = Bulletin of Pirogov national medical & Surgical center. 2012; 7(3):139–140 (in Russian).

3. Anjum A.S., Maqsood H., Younus S., Anjum S., Fatima M. A rare case of non-gestational metastatic ovarian choriocarcinoma: case report and literature review with a special emphasis on imaging. Cureus 2021; 13(2):e13121. https://doi.org/10.7759/cureus.13121

4. Nishino K., Yamamoto E., Ikeda Y., Niimi K., Kajiyama H. A poor prognostic metastatic nongestational choriocarcinoma of the ovary: a case report and the literature review. J. Ovarian. Res. 2021; 14:56. https://doi.org/10.1186/s13048-021-00810-3

5. Kaprina A.D., Ashrafyana L.A., Stilidi I.S., editors. [Gynecologic oncology: a national guideline]. Moscow: GEOTAR- Media; 2019 (in Russian). https://doi.org/10.33029/9704-5329-2-ONR-2019-1-384

6. Cronin S., Ahmed N., Craig A.D., King S., Huang M., Chu C.S., Mantia-Smaldone G.M. Non-gestational ovarian choriocarcinoma: a rare ovarian cancer subtype. Diagnostics (Basel) 2022; 12(3):560. https://doi.org/10.3390/diagnostics12030560

7. Wang L., Wan Y., Sun Y., Zhang X., Cheng X., Wu M., Liu G. Pure nongestational uterine choriocarcinoma in postmenopausal women: a case report with literature review. Cancer Biol. Ther. 2019; 20(9):1176–1182. https://doi.org/10.1080/15384047.2019.1617564

8. Malik R., Verma M., Chauhan M., Sinha P. Choriocarcinoma of the ovary masquerading as ectopic pregnancy. Gynecol. Minim. Invasive Ther. 2022; 11(4):247–249. https://doi.org/10.4103/gmit.gmit_93_21

9. Euscher E.D. Germ cell tumors of the female genital tract. Surg. Pathol. Clin. 2019; 12(2):621–649. https://doi.org/10.1016/j.path.2019.01.005

10. Sakurai S., Asano R., Furugori M., Shigeta H. A rare case of gestational ovarian choriocarcinoma coexistent with intrauterine pregnancy. Taiwan J. Obstet. Gynecol. 2022; 61(4):708–712. https://doi.org/:10.1016/j.tjog.2021.09.036

11. Liu X., Zhang X., Pang Y., Ma Y., Zhang X., Liu P. Clinicopathological factors and prognosis analysis of 39 cases of non-gestational ovarian choriocarcinoma. Arch. Gynecol. Obstet. 2020; 301:901–912. https://doi.org/10.1007/s00404-020-05502-9

12. Shao Y., Xiang Y., Jiang F., Wan X., Yang J., Feng F., Ren T., Zhao J. Clinical features of a Chinese female nongestational choriocarcinoma cohort: a retrospective study of 37 patients. Orphanet J. Rare Dis. 2020; 15:325. https://doi.org/10.1186/s13023-020-01610-6

13. Mar'yenko A.S., Artemenkova P.K., Kartavtseva T.A., Zeynalov R.A. [Trophoblastic disease]. Sibirskiy onkologicheskiy zhurnal = Siberian journal of oncology 2008; S1:85–86 (in Russian).

14. Yu X., Du Q., Zhang X., Liu Y., Shen Y. Pure primary non-gestational choriocarcinoma originating in the ovary: A case report and literature review. Rare Tumors. 2021; 13:20363613211052506. https://doi.org/10.1177/20363613211052506

15. Yee L.S., Zakaria R., Mohamad N., Fong O.W. Non-gestational choriocarcinoma of the ovary: A case report. J. Taibah Univ. Med. Sci. 2021; 16(4):632–636. https://doi.org/10.1016/j.jtumed.2021.01.001


Review

For citations:


Kovaleva Y.A., Nechaykin A.S., Abramova S.V., Labzina M.V. Non-gestational ovarian choriocarcinoma (a clinical case). Bulletin Physiology and Pathology of Respiration. 2024;(92):93-99. (In Russ.) https://doi.org/10.36604/1998-5029-2024-92-93-99

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ISSN 1998-5029 (Print)