Lung function in patients with asthma in the post-COVID period
https://doi.org/10.36604/1998-5029-2024-93-72-82
Abstract
Aim. To assess the lung function in patients with bronchial asthma (BA) after new-onset coronavirus infection.
Materials and methods. Fifty-five patients who underwent COVID-19 participated in the study under conditions of voluntary informed consent. The main group consisted of 30 patients with mild BA, the comparison group – 25 patients without chronic respiratory diseases (CRD). According to chest computed tomography (CT) findings, the degree of lung parenchyma involvement was classified as follows: mild COVID-19 (CT 0 stage) in 14 patients; moderate COVID-19 (CT 1-2 stages) in 27 patients; and severe COVID-19 (CT 3-4 stages) in 14 patients. Lung function tests were conducted once, adhering to both Russian and international standards.
Results. In patients with BA, obstructive pulmonary function impairment was predominant at CT 1-2 stages (79%), CT 0 stage (67%), and CT 3-4 stages (43%). Lung diffusion capacity (LDC) was impaired predominantly in CT 3-4 stages in both BA patients and those without CRD, occurring in 57% of cases. Analysis of lung function showed that LDC reduction was detected in 17% of BA cases and 24% of non-CRD cases. There were no statistically significant changes in pulmonary ventilation among BA patients with impaired LDC compared to patients without CRD.
Conclusion. All patients with respiratory symptoms after COVID-19 should undergo comprehensive lung function assessment to identify bronchial obstruction, impaired lung diffusion capacity, and ensure timely intervention.
About the Authors
E. E. Mineeva
Vladivostok Branch of Far Eastern Scientific Centre of Physiology and Pathology of Respiration – Institute of Medical Climatology and Rehabilitation Treatment
Russian Federation
Russian Federation
Elena E. Mineeva, MD, PhD (Med.), Staff Scientist, Laboratory of Rehabilitative Treatment, Vladivostok Branch of Far Eastern Scientific Center of Physiology
73g Russkaya Str., Vladivostok, 690105
M. V. Antonyuk
Vladivostok Branch of Far Eastern Scientific Centre of Physiology and Pathology of Respiration – Institute of Medical Climatology and Rehabilitation Treatment
Russian Federation
Russian Federation
Marina V. Antonyuk, MD, PhD, DSc (Med.), Professor, Head of Laboratory of Rehabilitative Treatment
73g Russkaya Str., Vladivostok, 690105
A. V. Yurenko
Vladivostok Branch of Far Eastern Scientific Centre of Physiology and Pathology of Respiration – Institute of Medical Climatology and Rehabilitation Treatment
Russian Federation
Russian Federation
Alla V. Yurenko, MD, PhD (Med.), Senior Staff Scientist, Laboratory of Rehabilitative Treatment
73g Russkaya Str., Vladivostok, 690105
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Review
For citations:
Mineeva E.E., Antonyuk M.V., Yurenko A.V. Lung function in patients with asthma in the post-COVID period. Bulletin Physiology and Pathology of Respiration. 2024;(93):72-82. (In Russ.) https://doi.org/10.36604/1998-5029-2024-93-72-82
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