Бронхиальная астма и COVID-19 (обзор литературы)

Проведен анализ и систематизация научной литературы, посвященной проблеме сочетания бронхиальной астмы (БА) и COVID-19 с использованием электронных баз данных PubMed/MEDLINE и eLIBRARY.RU. Показана противоречивость данных о связи между БА и COVID-19. Обсужден механизм развития воспаления и его особенности при новой коронавирусной инфекции. Подчеркнута важная роль натуральных и Т-натуральных киллеров в патогенезе заболевания. Сделан вывод о значимости типа воспаления при БА для риска заражения SARS-CoV-2. Представлена информация о двойственности сведений относительно применения ингаляционных глюкокортикостероидов при лечении БА у пациентов, болеющих COVID-19. В статье авторы приходят к заключению о том, что результаты имеющихся на сегодняшний день исследований не позволяют сделать однозначного вывода о большей предрасположенности к инфекции SARS-CoV-2 и о более тяжелом течении COVID-19 у больных бронхиальной астмой и, наоборот, о негативном влиянии COVID-19 на течение и контроль бронхиальной астмы. 

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