Estrogen receptors (review). Part 1
https://doi.org/10.12737/artide_5d0ad2e5d54867.15780111
Abstract
The article is a two-part review of the literature in which modern data on the receptors of the most important hormones during pregnancy, estrogens, are analyzed. The first part of the review describes the types of estrogen receptors and shows the features of their structure. Genomic and non-genomic mechanisms of hormone action are considered, which are realized through different types of receptors: nuclear and membrane-associated. There are also briefly characterized intracellular signaling pathways stimulated by estrogens. The paramount importance of accurate and dynamic regulation of the activity of hormones is emphasized. It was concluded that there is a necessity for further research of the estrogen receptors. The second part of the literature review focuses on the role of estrogen receptors during pregnancy.
About the Authors
I. V. Dovzhikova
Far Eastern Scientific Center of Physiology and Pathology of Respiration
Russian Federation
Russian Federation
Inna V. Dovzhikova - PhD, DSc, Leading staff scientist of Laboratory of Mechanisms of Etiopathogenesis and Recovery Processes of the Respiratory System at Non-Specific Lung Diseases.
22 Kalinina Str., Blagoveshchensk, 675000
I. A. Andrievskaya
Far Eastern Scientific Center of Physiology and Pathology of Respiration
Russian Federation
Russian Federation
22 Kalinina Str., Blagoveshchensk, 675000
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Review
For citations:
Dovzhikova I.V., Andrievskaya I.A. Estrogen receptors (review). Part 1. Bulletin Physiology and Pathology of Respiration. 2019;(72):120-127. (In Russ.) https://doi.org/10.12737/artide_5d0ad2e5d54867.15780111
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