The use of impulse oscillometry in patients with asthma

Introduction. Impulse oscillometry (IOS) is a novel method of assessing airway resistance. IOS has been introduced as an alternative technique to assess lung function.

Aim. To evaluate IOS for lung function assessment in patients with various severe degree of asthma.

Materials and methods. The study included patients (n=76) from 16 to 79 years old (mean age was 44±18; 52 (68%) for men and 24 (32%) for women) with asthma of various degree severity. IOS indices were compared with the indices of traditional pulmonary function tests (PFTs) such as spirometry, bodyplethys-mography and diffusing capacity of the lung.

Results. There were revealed the following changes of IOS: increasing of respiratory impedance (Zrs), respiratory resistance (Rrs), friction resistance (Rrs), its frequency dependence (Rrs5-Rrs20), square reactance (AX) and resonant frequency (fres), the decrease in reactance (Xrs) in 96% of patients with asthma. 12 out of 18 patients (67%) with traditional PFTs in normal values had deviations of IOS parameters Rrs, Xrs, АХ, (Rrs5-Rrs20). IOS parameters of patients with asthma showed significant correlations with parameters of spirometry and body-plethysmography.

Conclusion. IOS can be used for lung function assessment in patients with asthma. IOS may provide objective information in cases in which spirometry was normal.

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