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Estrogen receptors (review). Part 2.

https://doi.org/10.36604/1998-5029-2019-73-125-133

Abstract

The article is a two-part review of the literature in which modern data on the receptors of estrogens are analyzed. The first part of the review describes the types of estrogen receptors, their mechanisms of action and regulation. This part of the literature review focuses on the role of estrogen receptors during pregnancy. Particular attention is paid to the significance of estrogen receptors in the process of endometrial transformation during gestation. The role of receptors in ensuring the blood flow of the uterus is viewed. It is shown how estrogen receptors contribute to the labor. The evidence of receptor localization in different areas of the reproductive tract is recorded, hypotheses of the supposed role of different types of estrogen receptors in the placenta are presented. Analysis of literature data on the receptors in various complications of pregnancy allowed to conclude that this issue needs further study.

About the Authors

I. V. Dovzhikova
Far Eastern Scientific Center of Physiology and Pathology ofRespiration
Russian Federation

Inna V. Dovzhikova - PhD, D.Sc. (Biol.), Leading Staff Scientist of Laboratory of Mechanisms of Etiopathogenesis and Recovery Processes of the Respiratory System at Non-Specific Lung Diseases.

22 Kalinina Str., Blagoveshchensk, 675000




I. V. Andrievskaya
Far Eastern Scientific Center of Physiology and Pathology ofRespiration
Russian Federation

Irina A. Andrievskaya - PhD, D.Sc. (Biol.), Professor RAS, Head of Laboratory of Mechanisms of Etiopathogenesis and Recovery Processes of the Respiratory System at Non-Specific Lung Diseases.

22 Kalinina Str., Blagoveshchensk, 675000




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Review

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Dovzhikova I.V., Andrievskaya I.V. Estrogen receptors (review). Part 2. Bulletin Physiology and Pathology of Respiration. 2019;(73):125-133. (In Russ.) https://doi.org/10.36604/1998-5029-2019-73-125-133

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ISSN 1998-5029 (Print)