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CORRECTION OF DIAPHRAGM DYSFUNCTION IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE

https://doi.org/10.12737/article_5935fca0ee2974.18739498

Abstract

The aim of the study was to examine the influence of telmisartan on the condition of the diaphragm in patients with chronic obstructive pulmonary disease (COPD) at the stage of compensated chronic pulmonary heart (CPH). We examined 30 patients with COPD, complicated with CPH, who had the examination of pulmonary and intracardiac hemodynamics and the functional state of the diaphragm by means of ultrasound scanning. It was found that that the inclusion of telmisartan in the complex therapy of COPD patients with compensated CPH contributes to the normalization of systolic pressure in the pulmonary artery, the functional ability of the right ventricle, and values of the respiratory function. The application of telmisartan in a daily dose of 4 mg during 4 weeks while treating the patients with COPD complicated with compensated CPH leads to the improvement of the functional state of diaphragm, normalization of diaphragm excursion under forced respiration and contractility of diaphragm muscle, which gives an opportunity to increase the efficiency of treatment of these patients.

About the Authors

I. G. Menshikova
Amur State Medical Academy
Russian Federation


V. E. Perley
First Saint Petersburg State Medical University
Russian Federation


Y. V. Kvasnikova
Amur State Medical Academy
Russian Federation


I. V. Sklyar
Amur State Medical Academy
Russian Federation


E. V. Magalas
Amur State Medical Academy
Russian Federation


References

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For citations:


Menshikova I.G., Perley V.E., Kvasnikova Y.V., Sklyar I.V., Magalas E.V. CORRECTION OF DIAPHRAGM DYSFUNCTION IN PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE. Bulletin Physiology and Pathology of Respiration. 2017;(64):19-22. (In Russ.) https://doi.org/10.12737/article_5935fca0ee2974.18739498

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ISSN 1998-5029 (Print)