THE FEATURES OF CLINICAL COURSE AND PREVENTION OF COMPLICATIONS OF BRONCHIAL ASTHMA IN PATIENTS WITH MIXED-PATHOLOGY IN THE NORTH

Abstract

The aim of the research is to study the features of clinical course and prevention of complications in patients with bronchial asthma with mixed pathology. During 10 years, the clinical symptoms and the dynamics of spirometry parameters were estimated in the newly arrived to the North suffering from bronchial asthma with arterial hypertension. The patients were divided into 2 groups: the main one (47 people) and the control one (50 people). The patients of the main group regularly took budesonide/formoterol, tiotropium bromide; in the cold period of the year complex pulmonary rehabilitation was done to them to prevent the complications of bronchial asthma. The patients of the control group took beclometasone, fenoterol; the prevention of complications of bronchial asthma was carried out according to the standard program in the conditions of polyclinic. It was established that among newly arrived citizens of the North the combination of bronchial asthma with arterial hypertension was found out in 72% of women and 28% of men, arterial hypertension develops in them in 5-9 years. Mixed pathology leads to worsening of both diseases clinical course. In 10 years the progressing increase in the degree of bronchial obstruction in patients of the control group was revealed. The patients of the main group had a stabilization of spirography indicators, 78% of patients had bronchial asthma under control, whereas in the patients of the control group against the decrease of parameters of ventilation lungs function there was a whole or partial control of bronchial asthma only in 28% of patients. Antiasthmatic drug therapy brings adequate positive effect in the prevention of complications in patients with bronchial asthma and with arterial hypertension only in combination with complex rehabilitation program.