EFFECT FROM REAMBERIN TAKING IN THE COMPLEX TREATMENT OF THE INJURED WITH COMBINED AND MILTIPLE DISINTEGRATING PELVIC RING FRACTURE

Abstract

The aim of the study is the optimization of the treatment of patients with combined and multiple disintegrating fractures of the pelvic ring by adding antioxidants to the basic therapy. In the traumatology department the examination and treatment of 56 patients with combined and multiple disintegrating fracture of the pelvic ring was done; standard therapy was prescribed to 30 patients, and 26 patients also got antioxidants in the form of reamberin. It was found out that reamberin added into the complex therapy is accompanied by the antioxidant effect which by the end of the treatment reveals itself through statistically reliable decrease of diene conjugates content, lipid hydroperoxides and malonic dialdehyde in the blood plasma and through the increase of ceruloplasmin and E vitamin. The dynamics of clinical and laboratory indicators in patients against complex therapy with reamberin reflects a more fast stabilization of the patient already by the fourth day of treatment (in 2.4 and 3.9 times faster by APACHE II and SAPS II scales, respectively), in comparison with the patients who had standard therapy and had stabilization of their state only by the 10^th day of treatment. The application of reamberin in complex treatment of patients with severe combined and multiple fractures of the pelvic reliably decreases the dates of preoperative preparation, in-patient treatment and patients rehabilitation and also contributes to the lowering of the total number of somatic complications and reduction of their combination.