Preview

Bulletin Physiology and Pathology of Respiration

Advanced search

NEW METHOD OF X-RAY DIAGNOSTICS OF DISTURBANCES OF LUNGS VENTILATION FUNCTION BY MULTIDETECTOR COMPUTED TOMOGRAPHY

Abstract

The aim of the research is to develop a new method of quantitative assessment of lung ventilation function disturbances based on the analysis of 3D modeling of multidetector computed tomography results. The work deals with 3D volumetry, which is the new method of X-ray diagnostics of lung ventilation function disturbances. The methodology of conducting the diagnostics, the possibilities of its practical application to some diseases (chronic obstructive pulmonary disease, bronchial asthma, anomalies of lungs development and tuberculosis) at the example of specific researches are presented in the article. It is shown that the method of 3D volumetry based on the multidetector computed tomography has indisputable advantages not only in comparison with other methods of X-ray diagnostics but also with functional methods of research commonly accepted in diagnostics of lung ventilation function disturbances. This method has a bigger potential than traditional computed tomography and opens new possibilities of 3D modeling of multidetector computed tomography. Thus, for example, volumetry allows to make a quick assessment of the degree of lung ventilation function disturbances not only visually, but also quantitatively; the construction of 3D models gives an unquestionable advantage in comparison with traditional images at standard multidetector computed tomography. Due to 3D volumetry it has become possible to assess the function of each lung separately and if necessary the function of a separate part of the lung affected by the pathological process whether it is air cavity or a limited part of hyperinflation at the defects of lung development. The identification of pathological zones of hyperinflation in lungs can become the means of prediction of development and of clinical course of the pathological process, inflammation, and addition of the infection.

About the Authors

Andrey V. Il'in
Far Eastern Scientific Center of Physiology and Pathology of Respiration SB RAMS
Russian Federation


Anatoliy V. Lenshin
Far Eastern Scientific Center of Physiology and Pathology of Respiration SB RAMS
Russian Federation


Andrey N. Odireev
Far Eastern Scientific Center of Physiology and Pathology of Respiration SB RAMS
Russian Federation


Juliy M. Perelman
Far Eastern Scientific Center of Physiology and Pathology of Respiration SB RAMS
Russian Federation


References

1. Авдеев С.Н. Легочная гиперинфляция у больных ХОБЛ // Атмосфера. Пульмонология и аллергология. 2006. №2. С.11–16.

2. Ильин А.В., Леншин А.В. Дисплазии органов дыхания как фактор риска развития туберкулеза легких // Актуальные вопросы фтизиопульмонологии в Амурской области: сб. трудов обл. науч.-практ. конф. фтизиатров. Благовещенск, 2011. С.146‒152.

3. Прогрессирующая легочная дистрофия, как один из вариантов буллезной эмфиземы легких / А.В.Леншин [и др.] // Бюл. физиол. и патол. дыхания. 2012. Вып.45. С.104–114.

4. Несветов A.M. Клинико-рентгено-морфологическая характеристика ограниченных форм туберкулеза легких. Туберкулез и гипоплазия // Вестн. рентгенол. и радиол. 1994. №4. С.11–16.

5. Рентгеновская компьютерная томография в диагностике хронической обструктивной болезни легких / Г.Е.Труфанов [и др.]. СПб.: ЭЛБИ-СПб, 2009. 120 с.

6. Airway remodeling measured by multidetector computed tomography is increased in severe asthma and correlates with pathology / R.S.Aysola [et al.] // Chest. 2008. Vol.134, №6. P.1183–1191.

7. Investigation of airways using MDCT for visual and quantitative assessment in COPD patients / P.Brillet [et al.] // Int. J. Chron. Obstruct. Pulmon. Dis. 2008. Vol.3, №1. Р.97–107.

8. Franquet T. Técnicas de imagen en la exploración de la via aeréa pequeña: asma y EPOC // Arch. Broncopneumol. 2011. Vol.47. P.20–26.

9. Quantitative assessment of air trapping in chronic obstructive pulmonary disease using inspiratory and expiratory volumetric MDCT / S.Matsuoka [et al.] // Am. J. Roentgenol. 2008 Vol.190, №3. P.762–769.

10. Quantitative CT assessment of chronic obstructive pulmonary disease / S.Matsuoka [et al.] // Radiographics. 2010. Vol. 30, №1. P.55–66.


Review

For citations:


Il'in A.V., Lenshin A.V., Odireev A.N., Perelman J.M. NEW METHOD OF X-RAY DIAGNOSTICS OF DISTURBANCES OF LUNGS VENTILATION FUNCTION BY MULTIDETECTOR COMPUTED TOMOGRAPHY. Bulletin Physiology and Pathology of Respiration. 2013;(47):40-47. (In Russ.)

Views: 142


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1998-5029 (Print)