COMPARATIVE DESCRIPTION OF AMSEL AND NUGENT CRITERIA FOR THE DIAGNOSIS OF BACTERIAL VAGINOSIS

The study of correlation was done between the complaints character and the examination of bacterial vaginosis with the application of Amsel and Nugent criteria among 123 women who applied for gynecological help to prepare to the program of extracorporal fertilization and the conductance of preconception preparation. The first group included the patients with tubo-peritoneal form of infertility (n=41); the second group included the patients who suffered a failure of extracorporal fertilization (n=41); the third group (of comparison) included the women who came to a gynecologist to have preconception preparation (n=41). The algorithm of examination included the use of bacterioscopic and culture study and PCR-based diagnostics; pHmetry of the vaginal secretion was done. At the initial examination different complaints were made by 12 (29%) patients from the first group, 5 (12%) women from the second group and 7 (17%) patients from the third group. Bacterial vaginosis by Nugent criteria was found in 10 (24%) patients of the first group, 8 (20%) patients of the second group and 9 (22%) women of the third group. According to Amsel criteria bacterial vaginosis was found in 10 patients (24%) of the first group, in 7 patients (17%) of the second group and 9 patients (22%) of the third group. While conducting the additional study of microflora of the cervical canal, high frequency of U.Urealyticum and Candida albicans in patients of the first group was found in 35 cases (85%), in patients of the second group in 19 cases (46%) and in women of the third group only in 5 cases (12%). The obtained results prove that in women with tubo-peritoneal form of infertility the frequency of bacterial vaginosis was higher (р<0.05) than in other groups of women who planned to go through assisted reproductive technology. Reliable differences between diagnostic criteria of Amsel and Nugent to diagnose bacterial vaginosis were not revealed. At the treatment of bacterial vaginosis it is necessary to have an additional examination to find conditioned pathogen flora to cure dysbiosis of vagina caused not only by the decrease of lactobacillus number but by the increase of the growth of conditioned pathogen microorganisms.

бактериальный вагиноз, критерий Амселя, критерий Ньюджента, условно-патогенная флора, bacterial vaginosis, Amsel criterion, Nugent criterion, conditioned-pathogenic flora

1. Байрамова Г.Н. Бактериальный вагиноз // Практическая гинекология / под ред. В.И.Кулакова, В.Н.Прилепской. М.: МЕДпресс-информ 2001; С.189-200.

2. Воропаева Е.Е. Клинико-морфологические аспекты оптимизации лечения бактериального вагиноза, ассоциированного с хроническими воспалительными заболеваниями матки: автореф. дис.. канд. мед. наук. Челябинск, 2005. 14 с.

3. Гомберг М.А. Бактериальный вагиноз и новые инфекции, с ним ассоциированные // Рос. вестник акуш.-гин. 2010. Т.10, №2. С.32-34.

4. Липова Е.В., Радзинский В.Е. Бактериальный вагиноз: всегда дискуссии // Status Praesens. 2012. №7.С.27-34.

5. Использование метода прямой микроскопии урогенитальных мазков на амбулаторном приеме с целью оптимизации диагностики урогенитальных инфекций / А.М.Савичева [и др.] // Трудный пациент. 2008. №1. С.13-14.-

6. Шуршалина А.В. Хронический эндометрит у женщин с патологией репродуктивной функции: автореф. дис.. д-ра мед. наук. Москва, 2007. 12 с.

7. The accuracy of various tests for bacterial vaginosis in predicting preterm birth: a systematic review / Н.Honest [et al.] // BJOG: An International Journal of Obstetrics and Gynaecology. 2004. Vol.111, №5. Р.409-422.

8. Diagnosis of bacterial vaginosis in cases of abnormal vaginal discharge: comparison of clinical and microbiological criteria / Т.Modak [et al.] // J. Infect. Dev. Ctries. 2011. Vol.5, №5. P.353-360.

9. Turovskiy Y, Sutyak Noll K., Chikindas M.L. The aetiology of bacterial vaginosis // J. Appl. Microbiol. 2011. Vol.110, №5. Р.1105-1128.

10. Correlation between squamous intraepithelial lesions (SILs) and bacterial vaginosis / G.Vetrano [et al.] // Eur. J. Gynaecol. Oncol. 2007. Vol.28, №4. P.310-312.

11. Accuracy of Amsel's Criteria in the Diagnosis of Bacterial Vaginosis (Preliminary Report) / M.Yaghmaei [et al.] // The Iranian Journal of Obstetrics, Gynecology and Infertility. 2009. Vol.12, №3. Р.17-22.