EFFECTS OF TOBACCO SMOKING ON HEALTH-RELATED QUALITY OF LIFE IN PATIENTS WITH ASTHMA
Abstract
In order to assess the impact of cigarette smoking on health-related quality of life in patients with asthma, 96 patients divided into three groups were examined: active smokers, ex-smokers and non-smokers. Quality of life was assessed using the SF-36 and AQLQ questionnaires, the state of the emotional sphere by means of the Hospital Anxiety and Depression Scale. The level of asthma control was determined by questionnaire ACT. Respiratory function was assessed by spirometry. The study found that smokers are characterized by significantly lower levels of general and specific quality of life associated with impaired patency of the distal airways. They are characterized by great severity of anxiety and depression, which are, according to the correlation analysis, one of the leading factors in reducing the quality of life of patients. Regression models were developed to reflect the relationship of the individual domains of general and specific quality of life with the levels of anxiety and depression. Quitting Smoking cessation contributes to a significant improvement in the quality of life and asthma control.
About the Author
Natal'ya L. Perelman
Far Eastern Scientific Center of Physiology and Pathology of Respiration SB RAMS
Russian Federation
Russian Federation
References
1. Перельман Н.Л. Влияние тревоги и депрессии на качество жизни больных бронхиальной астмой с холодовой гиперреактивностью дыхательных путей // Дальневост. мед. журн. 2009. №4. С.6−10.
2. Перельман Н.Л. Влияние тревожно-депрессивных состояний на достижение контроля над заболеванием у больных бронхиальной астмой // Бюл. физиол. и патол. дыхания. 2010. Вып.37. С.21−24.
3. Perelman J.M., Perelman N.L. Influence of depression and cold airway hyperresponsiveness on quality of life in patients with bronchial asthma during winter // Eur. Resp. J. 2010. Vol.36, Suppl.54. P.3813.
4. Ульянычев Н.В. Автоматизированная система для научных исследований в области физиологии и патологии дыхания человека. Новосибирск: Наука, 1993. 246 с.
5. Factors influencing quality of life in asthmatics--a case-control study / A.Al-kalemji [et al.] // Clin. Respir. J. 2013. Vol.7, №3. P.288−296.
6. The correlation between asthma control and health status: the GOAL study / E.D.Bateman [et al.] // Eur. Respir. J. 2007. Vol.29, №1. P.56−62.
7. The impact of GINA suggested drugs for the treatment of asthma on Health-Related Quality of Life: a GALEN review / I.Baiardini [et al.] // Allergy. 2008. Vol.63, №8. P.1015−1030.
8. Smoking and airway inflammation in patients with mild asthma / G.V.Chalmers [et al.] // Chest. 2001. Vol.120. P.1917-1922.
9. Chapman S. Stop-smoking clinics: a case for their abandonment // Lancet. 1985. Vol.1. P.918-920.
10. Asthma control, severity, and quality of life: quantifying the effect of uncontrolled disease / H.Chen [et al.] // J. Allergy Clin. Immunol. 2007. Vol.120, №2. P.396−402.
11. Global Initiative for Asthma (GINA). Global strategy for asthma management and prevention (Update 2014). URL: http://www.ginasthma.com.
12. Asthma and mental disorders in primary care / R.D.Goodwin [et al.] // Gen. Hosp. Psychiatry. 2003. Vol.25. P.479−483.
13. Validation of a standardized version of the Asthma Quality of Life Questionnaire / E.F.Juniper [et al.] // Chest. 1999. Vol.115. P.1265−1270.
14. Relationship between quality of life and clinical status in asthma: a factor analysis / E.F.Juniper [et al.] // Eur. Respir. J. 2004. Vol. 23, №2. P.287−291.
15. What’s worse for asthma control and quality of life: depressive disorders, anxiety disorders, or both? / K.L.Lavoie [et al.] // Chest. 2006. Vol.130. P.1039−1047.
16. Determinants for a low health-related quality of life in asthmatics / M.Leander [et al.] // Ups. J. Med. Sci. 2012. Vol.117, №1. P.57−66.
17. Use of a preference-based measure of health (EQ-5D) in COPD and asthma / A.S.Pickard [et al.] // Respir. Med. 2008. Vol.102, №4. P.519−536.
18. Rietveld S., van Beest I., Everaerd W. Stress-induced breathlessness in asthma // Psychol. Med. 1999. Vol.29, №6. P.1359−1366.
19. The role of acute and chronic stress in asthma attacks in children / S. Sandberg [et al.] // Lancet. 2000. Vol.356, №9234. P.982−987.
20. Thomson N.C., Chaudhuri R., Livingston E. Asthma and cigarette smoking // Eur. Respir. J. 2004. Vol.24, №5. Р.822−833.
21. Global asthma prevalence in adults: findings from the cross-sectional world health survey / T.To [et al.] // BMC Public Health. 2012. Vol.12. Р.204.
22. Cigarette smoke enhances Th-2 driven airway inflammation and delays inhalational tolerance / C.L.Van Hove [et al.] // Respir. Res. 2008. Vol.9. Р.42.
23. Ware J.E. SF-36 Health Survey. Manual and interpretation guide. Second printing. Boston: The Health Institute, New England Medical Center, 1997.
24. Zigmond A.S., Snaith R.P. The hospital anxiety and depression scale // Acta Psychiatr. Scand. 1983. Vol.67, №6. P.361−370.
Review
For citations:
Perelman N.L. EFFECTS OF TOBACCO SMOKING ON HEALTH-RELATED QUALITY OF LIFE IN PATIENTS WITH ASTHMA. Bulletin Physiology and Pathology of Respiration. 2014;(53):30-35. (In Russ.)
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