Difficulties in diagnosing multiple myeloma with lung damage
https://doi.org/10.36604/1998-5029-2021-79-103-109
Abstract
Multiple myeloma occupies a leading position among malignant blood diseases. There is clinical evidence that multiple myeloma can be complicated by secondary amyloidosis. The article presents a clinical case for the diagnosis of multiple myeloma complicated by secondary pulmonary amyloidosis. The participation of doctors of various specialties (pulmonologist, hematologist, pathologist), the use of high-tech diagnostic methods (histological examination of a biopsy of lung tissue, trepanobiopsy, immunohistochemical examination of histological preparations of lungs and bone marrow), made it possible to establish a clinical diagnosis.
Keywords
multiple myeloma,
secondary amyloidosis,
lung amyloidosis,
immunohistochemistry,
immunochemical analysis,
lambda-light chains
Supporting agencies: This study was not sponsored
About the Authors
I. V. Demko
Krasnoyarsk State Medical University;
Krasnoyarsk Regional Clinical Hospital
Russian Federation
Russian Federation
Irina V. Demko, MD, PhD, DSc (Med.), Professor, Head of Department of Hospital Therapy and Immunology with Postgraduate Education Course; Head of Pulmonary Allergology Сenter
1 Partizana Zheleznyaka Str., Krasnoyarsk, 660022;
3 Partizana Zheleznyaka Str., Krasnoyarsk, 660022
M. G. Mamaeva
Krasnoyarsk State Medical University;
Krasnoyarsk Regional Clinical Hospital
Russian Federation
Russian Federation
Marina G. Mamaeva, MD, PhD (Med.), Assistant of Department of Hospital Therapy and Immunology with Postgraduate Education Course; Pulmonologist of Department of Pulmonology
1 Partizana Zheleznyaka Str., Krasnoyarsk, 660022;
3 Partizana Zheleznyaka Str., Krasnoyarsk, 660022
A. Yu. Kraposhina
Krasnoyarsk State Medical University;
Krasnoyarsk Regional Clinical Hospital
Russian Federation
Russian Federation
Angelina Yu. Kraposhina, MD, PhD (Med.), Associate Professor of Department of Hospital Therapy and Immunology with Postgraduate Education Course; Pulmonologist of Department of Pulmonology
1 Partizana Zheleznyaka Str., Krasnoyarsk, 660022;
3 Partizana Zheleznyaka Str., Krasnoyarsk, 660022
I. A. Solovieva
Krasnoyarsk State Medical University;
Krasnoyarsk Regional Clinical Hospital
Russian Federation
Russian Federation
Irina A. Solovieva, MD, PhD, DSc (Med.), Associate Professor of Department of Hospital Therapy and Immunology with Postgraduate Education Course; Pulmonologist of Department of Pulmonology
1 Partizana Zheleznyaka Str., Krasnoyarsk, 660022;
3 Partizana Zheleznyaka Str., Krasnoyarsk, 660022
N. V. Gordeeva
Krasnoyarsk State Medical University;
Krasnoyarsk Regional Clinical Hospital
Russian Federation
Russian Federation
Natalya V. Gordeeva, MD, PhD (Med.), Associate Professor of Department of Hospital Therapy and Immunology with Postgraduate Education Course; Pulmonologist of Department of Pulmonology
1 Partizana Zheleznyaka Str., Krasnoyarsk, 660022;
3 Partizana Zheleznyaka Str., Krasnoyarsk, 660022
V. V. Dyatlovskij
Krasnoyarsk State Medical University
Russian Federation
Russian Federation
Vadim V. Dyatlovskij, 6 th year Student of Medical Faculty
1 Partizana Zheleznyaka Str., Krasnoyarsk, 660022
S. A. Sidorov
Krasnoyarsk State Medical University
Russian Federation
Russian Federation
Semen А. Sidorov, 6 th year Student of Medical Faculty
1 Partizana Zheleznyaka Str., Krasnoyarsk, 660022
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Review
For citations:
Demko I.V., Mamaeva M.G., Kraposhina A.Yu., Solovieva I.A., Gordeeva N.V., Dyatlovskij V.V., Sidorov S.A. Difficulties in diagnosing multiple myeloma with lung damage. Bulletin Physiology and Pathology of Respiration. 2021;(79):103-109. (In Russ.) https://doi.org/10.36604/1998-5029-2021-79-103-109
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