Medico-social characteristic of pregnant women with dysbiosis in genital tract

The study was aimed to identify the impact of living conditions, primarily social conditions (education, employment, housing conditions, economic status and other relations) on pregnant women of the Amur region with genital tract dysbiosis in combination with urogenital mycoplasmas. 75 pregnant women were examined, 32 of them (the main group) were diagnosed with dysbiosis (Lactobacillus spp. <10⁶ GE/ml) with detected urogenital mycoplasmas (Ureaplasma spp. and Mycoplasma hominis) at clinically significant concentrations (≥10⁴ GE/ml). The control group consisted of 43 pregnant women with normocenosis (Lactobacillus spp. ≥10⁶ GE/ml). The analysis of medical and social factors revealed that women with genital tract dysbiosis in most cases live on the territory of the Amur region since birth, among them there were patients who had a second or third marriage who assessed their living conditions and material security as unsatisfactory, and the relationship with the husband as satisfactory (against the good ones in the control group); these women also smoked during pregnancy and often had physical activity at work both before and during pregnancy. Almost half of the women in the main group were unemployed. Women with genital dysbiosis were significantly more likely to undergo intrauterine intervention to terminate an unwanted pregnancy, and delivery by cesarean section was 4.1 times more likely than in the control group. The intensity of the influence of medical and social risk factors for infection of the genital tract with urogenital mycoplasmas was assessed.

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