THE ANALYSIS OF INFECTIOUS COMPLICATIONS OF HEMOBLASTOSIS IN THE AMUR REGION
Abstract
The analysis of infectious complications in 574 cancer patients receiving chemotherapy in soft hematology department of the Amur Regional Hospital was conducted in 2002-2011. In patients with acute lymphoblastic leukemia infectious complications were reported in 88% of cases at the time of induction of remission; during the re-induction of remission and consolidation they were in 40%; in patients with acute non lymphoblastic leukemia they were in 90% of cases at the time of induction of remission, in 80% during the consolidation of remission, and in 10% of cases during maintenance therapy; in patients with chronic lymphocytic leukemia they were in 85%; in patients with multiple myeloma they were in 40%, and at non-Hodgkin’s lymphomas they were in 50%. The most frequent complication of hemoblastosis is febrile neutropenia, mucositis, and pneumonia. The most severe complications are pneumonia, sepsis and necrotizing enteropathy. The features of the course and prognosis of these diseases were analyzed. At the appropriate sanitary and hygienic conditions, modern antibacterial medications, granulocytic and colony-stimulating medications and other therapies, the prognosis of the infectious complications of hemoblastosis at the absence of uncontrolled tumor growth is in most cases favorable.
About the Authors
Valeriy V. Voytsekhovskiy
Amur State Medical Academy
Russian Federation
Russian Federation
Anna V. Gruzdova
Amur State Medical Academy
Russian Federation
Russian Federation
Ekaterina A. Filatova
Amur Regional Clinical Hospital; Amur State Medical Academy
Russian Federation
Russian Federation
Nikolay D. Goborov
Amur State Medical Academy
Russian Federation
Russian Federation
Natal’ya V. Makarova
Amur Regional Clinical Hospital
Russian Federation
Russian Federation
Anastasiya A. Sinyuk
Amur Regional Clinical Hospital
Russian Federation
Russian Federation
Anna P. Kondrakhina
Amur State Medical Academy
Russian Federation
Russian Federation
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Review
For citations:
Voytsekhovskiy V.V., Gruzdova A.V., Filatova E.A., Goborov N.D., Makarova N.V., Sinyuk A.A., Kondrakhina A.P. THE ANALYSIS OF INFECTIOUS COMPLICATIONS OF HEMOBLASTOSIS IN THE AMUR REGION. Bulletin Physiology and Pathology of Respiration. 2012;(46):64-68. (In Russ.)
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